02.09.2014 Views

Protocol for the Derivation of Environmental and Human ... - CCME

Protocol for the Derivation of Environmental and Human ... - CCME

Protocol for the Derivation of Environmental and Human ... - CCME

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

Lipophile: A substance that tends to dissolve in organic, non-polar<br />

solvents. Lipophilic substances generally have very low water<br />

solubility.<br />

LO(A)EL (Lowest observed (adverse) effect level): The lowest dose<br />

in a bioassay that results in observed effects in <strong>the</strong> exposed<br />

organisms. In some cases, observed effects may be <strong>of</strong><br />

questionable impact or possibly beneficial. There<strong>for</strong>e, obvious<br />

negative effects may be differentiated as "adverse".<br />

LOEC (Lowest Observed Effect Concentration): The lowest<br />

concentration <strong>of</strong> a chemical used in a toxicity test that has a<br />

statistically significant adverse effect on test organisms relative<br />

to a control.<br />

Log K ow (Log n-Octanol/Water Partition Coefficient): The logarithm<br />

(base 10) <strong>of</strong> <strong>the</strong> ratio <strong>of</strong> a substance's solubility in n-octanol <strong>and</strong><br />

in water at equilibrium; also expressed as log P. Log K ow<br />

indicates a substance's tendency to bioaccumulate in terrestrial<br />

<strong>and</strong> aquatic biota.<br />

Long-term exposure: Exposure to a contaminant in a medium lasting<br />

from several weeks to years <strong>and</strong> <strong>of</strong>ten includes a reproductive<br />

or life cycle <strong>of</strong> <strong>the</strong> test organism. Usually referred to as a<br />

chronic exposure. Absolute definitions <strong>for</strong> this term vary among<br />

studies (see Part A, 3.1).<br />

MMM<br />

Macronutrient: A chemical necessary in large amounts, usually greater<br />

than 1 ppm, <strong>for</strong> plant growth.<br />

Mineralization: The decomposition <strong>of</strong> an element from an organic to an<br />

inorganic state.<br />

Mineral soil: A soil consisting predominantly <strong>of</strong> mineral matter (organic<br />

carbon < 17%), except <strong>for</strong> an organic surface layer that may be<br />

up to 40 cm thick.<br />

Multimedia exposure assessment: The quantitative estimate <strong>of</strong> total<br />

exposure to a chemical arising from all sources (air, water, soil,<br />

food, consumer products), by all routes (ingestion, inhalation,<br />

dermal absorption).<br />

xi

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!