Protocol for the Derivation of Environmental and Human ... - CCME
Protocol for the Derivation of Environmental and Human ... - CCME
Protocol for the Derivation of Environmental and Human ... - CCME
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<strong>and</strong> medicines). Estimated daily intake <strong>of</strong> a chemical is<br />
determined through a multimedia exposure assessment.<br />
Evapotranspiration: The loss <strong>of</strong> water from a given area during a<br />
specified period by evaporation from <strong>the</strong> soil surface <strong>and</strong> by<br />
transpiration from plants.<br />
Exposure: Contact between a substance <strong>and</strong> an individual or<br />
population. Exposure may occur via different routes including<br />
ingestion, dermal absorption, <strong>and</strong> inhalation.<br />
Exposure characterization: Identification <strong>of</strong> <strong>the</strong> conditions <strong>of</strong> contact<br />
between a substance <strong>and</strong> an individual or population. Exposure<br />
characteristics may involve identifying concentration, routes <strong>of</strong><br />
uptake, target sources, environmental pathways, <strong>and</strong> <strong>the</strong><br />
population at risk.<br />
Exposure estimation: Estimate <strong>of</strong> <strong>the</strong> amount <strong>and</strong> duration <strong>of</strong> contact<br />
between a substance <strong>and</strong> an individual or a population.<br />
Exposure estimates consider factors like concentration, routes<br />
<strong>of</strong> uptake, target sources, environmental pathways, population<br />
at risk, <strong>and</strong> time scale.<br />
Exposure pathway: The route by which an organism comes into<br />
contact with a contaminant. In <strong>the</strong> ecological effects-based<br />
procedure, exposure pathways are restricted to organisms in<br />
contact with contaminated soil. In <strong>the</strong> human health-based<br />
procedure, exposure pathways include contact through<br />
consumption <strong>of</strong> contaminated food, direct soil ingestion, dust<br />
inhalation, <strong>and</strong> dermal absorption.<br />
Exposure route: The mode <strong>of</strong> entry <strong>of</strong> a chemical into <strong>the</strong> body. The<br />
three basic exposure routes are ingestion, inhalation, <strong>and</strong> dermal<br />
absorption.<br />
Exposure scenario: A clearly <strong>and</strong> quantitatively defined description <strong>of</strong><br />
all circumstances associated with a receptor that would permit<br />
<strong>the</strong> estimation <strong>of</strong> chemical exposure. These circumstances<br />
include amount <strong>of</strong> air brea<strong>the</strong>d, food <strong>and</strong> water consumed, soil<br />
ingested, <strong>and</strong> <strong>the</strong> critical receptor's weight, age, sex, <strong>and</strong> all<br />
o<strong>the</strong>r relevant considerations.<br />
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