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Protocol for the Derivation of Environmental and Human ... - CCME

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<strong>and</strong> medicines). Estimated daily intake <strong>of</strong> a chemical is<br />

determined through a multimedia exposure assessment.<br />

Evapotranspiration: The loss <strong>of</strong> water from a given area during a<br />

specified period by evaporation from <strong>the</strong> soil surface <strong>and</strong> by<br />

transpiration from plants.<br />

Exposure: Contact between a substance <strong>and</strong> an individual or<br />

population. Exposure may occur via different routes including<br />

ingestion, dermal absorption, <strong>and</strong> inhalation.<br />

Exposure characterization: Identification <strong>of</strong> <strong>the</strong> conditions <strong>of</strong> contact<br />

between a substance <strong>and</strong> an individual or population. Exposure<br />

characteristics may involve identifying concentration, routes <strong>of</strong><br />

uptake, target sources, environmental pathways, <strong>and</strong> <strong>the</strong><br />

population at risk.<br />

Exposure estimation: Estimate <strong>of</strong> <strong>the</strong> amount <strong>and</strong> duration <strong>of</strong> contact<br />

between a substance <strong>and</strong> an individual or a population.<br />

Exposure estimates consider factors like concentration, routes<br />

<strong>of</strong> uptake, target sources, environmental pathways, population<br />

at risk, <strong>and</strong> time scale.<br />

Exposure pathway: The route by which an organism comes into<br />

contact with a contaminant. In <strong>the</strong> ecological effects-based<br />

procedure, exposure pathways are restricted to organisms in<br />

contact with contaminated soil. In <strong>the</strong> human health-based<br />

procedure, exposure pathways include contact through<br />

consumption <strong>of</strong> contaminated food, direct soil ingestion, dust<br />

inhalation, <strong>and</strong> dermal absorption.<br />

Exposure route: The mode <strong>of</strong> entry <strong>of</strong> a chemical into <strong>the</strong> body. The<br />

three basic exposure routes are ingestion, inhalation, <strong>and</strong> dermal<br />

absorption.<br />

Exposure scenario: A clearly <strong>and</strong> quantitatively defined description <strong>of</strong><br />

all circumstances associated with a receptor that would permit<br />

<strong>the</strong> estimation <strong>of</strong> chemical exposure. These circumstances<br />

include amount <strong>of</strong> air brea<strong>the</strong>d, food <strong>and</strong> water consumed, soil<br />

ingested, <strong>and</strong> <strong>the</strong> critical receptor's weight, age, sex, <strong>and</strong> all<br />

o<strong>the</strong>r relevant considerations.<br />

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