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Protocol for the Derivation of Environmental and Human ... - CCME

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Appendix B<br />

carcinogenic, <strong>the</strong>n <strong>the</strong> total exposure should not exceed <strong>the</strong> risk specific dose <strong>for</strong> a cancer risk <strong>of</strong> 10 -6 .<br />

The equations <strong>for</strong> this estimation are given in <strong>the</strong> following Section 4.1.<br />

4.1 Non-carcinogens<br />

Agricultural Site<br />

For an agricultural site, <strong>the</strong> Subcommittee proposed that 100% <strong>of</strong> <strong>the</strong> milk, <strong>and</strong> 50% <strong>of</strong> garden produce<br />

<strong>and</strong> meat are produced or grown on site. The total intake <strong>of</strong> contaminant is calculated based on <strong>the</strong>se<br />

assumptions. These estimates provide <strong>the</strong> total (background <strong>and</strong> on-site) exposure from those food<br />

sources. Generic guidelines <strong>for</strong> an agricultural setting are assumed to protect against exposure from local<br />

garden produce, <strong>and</strong> meat <strong>and</strong> milk.<br />

I p = intake <strong>of</strong> contaminant from produce grown on-site + intake <strong>of</strong> contaminant from produce<br />

grown <strong>of</strong>f-site<br />

I b = intake <strong>of</strong> contaminant from meat produced on-site + intake <strong>of</strong> contaminant from meat<br />

produced <strong>of</strong>f-site<br />

I m = intake <strong>of</strong> contaminant from milk produced on-site + intake <strong>of</strong> contaminant from milk<br />

produced <strong>of</strong>f site<br />

In estimating <strong>the</strong> total intake <strong>of</strong> a contaminant from all food sources at an agricultural site, <strong>the</strong><br />

background intake <strong>of</strong> produce, meat, <strong>and</strong> milk must be removed because <strong>the</strong> above equations include<br />

on-site <strong>and</strong> <strong>of</strong>f-site exposure.<br />

Where:<br />

T R = T F - (I BP + I BB + I BM ) [12]<br />

T R = Total estimated intake <strong>of</strong> contaminant from food o<strong>the</strong>r than produce, meat, <strong>and</strong><br />

milk<br />

T F = Total estimated intake <strong>of</strong> contaminant from food (from multi-media exposure<br />

assessment)<br />

I BP = Background intake <strong>of</strong> contaminant in produce (from multi-media exposure<br />

assessment)<br />

I BB = Background intake <strong>of</strong> contaminant in meat (from multi-media exposure<br />

assessment)<br />

I BM = Background intake <strong>of</strong> contaminant in milk (from multi-media exposure<br />

assessment)<br />

135

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