Protocol for the Derivation of Environmental and Human ... - CCME

Section 2
Investigation of Contaminant Toxicology....................................................................................69
2.1 Non-threshold Contaminants.............................................................................................71
2.1.1 Guidelines for Classification of Carcinogenicity and of Mutagenicity in
Germ Cells .......................................................................................................................72
2.2 Threshold Contaminants....................................................................................................72
Section 3
Exposure to Contaminants............................................................................................................75
3.1 Exposure to Mixtures of Chemicals ...................................................................................75
3.2 Determining Estimated Daily Intake ...................................................................................75
Section 4
Exposure Scenarios.......................................................................................................................78
4.1 Assumptions about Exposure ............................................................................................78
4.1.1 Threshold Contaminants....................................................................................................80
4.1.2 Non-threshold Contaminants.............................................................................................80
4.2 Absorption of Chemicals into the Body..............................................................................82
4.3 Receptors, Exposure Pathways, and Land Uses ................................................................82
4.3.1 General.............................................................................................................................82
4.3.2 Defined Scenario for Agricultural Land Use.......................................................................84
4.3.3 Defined Scenario for Residential/Parkland Land Uses........................................................84
4.3.4 Defined Scenario for Commercial Land Use......................................................................84
4.3.5 Defined Scenario for Industrial Land Use...........................................................................88
Section 5
Preliminary Guidelines Derivation...............................................................................................90
5.1 Preliminary Soil Guidelines Derivation for Threshold Substances.........................................90
5.2 Preliminary Soil Guidelines Derivation for Non-threshold Substances..................................91
5.3 Indirect Soil Contaminant Exposure...................................................................................91
5.3.1 General.............................................................................................................................91
5.3.2 Evaluation of Derived Guidelines Relative to Guidelines for Canadian Drinking Water Quality92
5.3.2.1 General.............................................................................................................................92
5.3.2.2 Methodology....................................................................................................................92
5.3.2.3 Data Requirements............................................................................................................94
5.3.2.4 Acceptability of Soil Guidelines .........................................................................................95
5.3.3 Evaluation for Contamination of Produce, Milk, and Meat..................................................96
5.3.4 Evaluation for Contamination of Indoor Air by Volatilization...............................................96
5.3.5 Off-site Migration of Soil/Dust from Industrial Sites............................................................98
Section 6
Derivation of the Final Human Health Soil Quality Guidelines..................................................99
6.1 Agricultural Land Use .......................................................................................................99
6.2 Residential/Parkland and Commercial Land Uses...............................................................99
6.3 Industrial Land Use...........................................................................................................99
xvi