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Mental health policy and practice across Europe: an overview

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Psychopharmaceuticals in <strong>Europe</strong> 181<br />

<strong><strong>an</strong>d</strong> not by GPs. At the same time the UK’s National Institute for Clinical Excellence<br />

(NICE) advised that while those adults diagnosed with moderate depression<br />

in primary care should be offered generic forms of SSRI <strong>an</strong>tidepress<strong>an</strong>ts, the<br />

risks had to be carefully explained <strong><strong>an</strong>d</strong> monitored, <strong><strong>an</strong>d</strong> that those with mild<br />

depression should be treated initially with ‘watchful waiting’, perhaps advising<br />

exercise, self-help <strong><strong>an</strong>d</strong> cognitive-behavioural therapy, but not the use of <strong>an</strong><br />

<strong>an</strong>tidepress<strong>an</strong>t, as the risk-benefit ratio was considered to be poor (National<br />

Institute for Clinical Excellence 2004). By that time, criticisms were mounting,<br />

not only of the reliability of published evidence of risk-benefit ratios for SSRIs,<br />

but of the difficulties of withdrawing from this medication – not dependency as<br />

is often suggested, but the severe <strong><strong>an</strong>d</strong> unpleas<strong>an</strong>t physical effects – pains, sweating,<br />

nausea <strong><strong>an</strong>d</strong> much more – which occur when patients who have been taking<br />

these drugs for a while cease to take them, no doubt caused by the fact that<br />

the molecules act very widely in the body, <strong><strong>an</strong>d</strong> the artificial raising of the levels<br />

by the drugs leads to a down-regulation of the body’s own production of, or<br />

sensitivity to, the molecules in question. 24 These cycles of enthusiasm, doubt,<br />

sc<strong><strong>an</strong>d</strong>al <strong><strong>an</strong>d</strong> warning are familiar from the history of the introduction of other<br />

psychiatric drugs, notably the minor tr<strong>an</strong>quillizers. They are usually followed by<br />

routinization of the uses of these drugs at lower but stable levels, out of the glare<br />

of publicity. And, while such public controversies may reshape the details of<br />

prescribing <strong>practice</strong>s <strong><strong>an</strong>d</strong> the populations to which different drugs are directed,<br />

they are unlikely to challenge the basic presuppositions of biological psychiatry,<br />

its rise to domin<strong>an</strong>ce, <strong><strong>an</strong>d</strong> the value, both cognitive <strong><strong>an</strong>d</strong> therapeutic, that it<br />

accords to neurochemical expl<strong>an</strong>ations <strong><strong>an</strong>d</strong> pharmaceutical treatment of mental<br />

<strong>health</strong> problems.<br />

Conclusions<br />

In one sense, developments in psychiatric drug use are merely one dimension of<br />

a new set of relations between ideas of <strong>health</strong> <strong><strong>an</strong>d</strong> illness, <strong>practice</strong>s of treatment<br />

<strong><strong>an</strong>d</strong> prevention of bodily malfunctions, <strong><strong>an</strong>d</strong> commercially driven innovation,<br />

marketing <strong><strong>an</strong>d</strong> competition for profits <strong><strong>an</strong>d</strong> shareholder value. But they take a<br />

specific character in relation to mental <strong>health</strong>. As we all know, in the second half<br />

of the twentieth century, psychotherapy <strong><strong>an</strong>d</strong> counselling became big business.<br />

But psychiatry itself – in the mental hospitals, the clinics, the GP surgeries <strong><strong>an</strong>d</strong><br />

the private psychiatric consulting room – also became a huge <strong><strong>an</strong>d</strong> profitable<br />

market for the pharmaceutical industry. These developments have continued<br />

into the present century. It would be misleading to claim that all ways of underst<strong><strong>an</strong>d</strong>ing<br />

mental <strong>health</strong> problems are ‘biological’ in the way I have described in<br />

this chapter. Indeed, recent developments suggest some reconciliations between<br />

bio-medical <strong><strong>an</strong>d</strong> social frameworks for underst<strong><strong>an</strong>d</strong>ing mental <strong>health</strong> problems,<br />

notably through the mediation of the versatile idea of ‘stress’. But even where<br />

practitioners adopt different underst<strong><strong>an</strong>d</strong>ings of the aetiology of such problems,<br />

in almost all cases treatment involves the use of drugs.<br />

Because contemporary psychiatry is so much the outcome of developments in<br />

psychopharmacology, commercial decisions are actually shaping the patterns<br />

of psychiatric thought at a very fundamental level. Most pharmaceutical

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