European Journal of Medical Research - Deutsche AIDS ...

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June 27, 2007 EUROPEAN JOURNAL OF MEDICAL RESEARCH 29 women (-36.0/L vs. -27.1/L in males, p
30 EUROPEAN JOURNAL OF MEDICAL RESEARCH June 27, 2007 Method of data collection will be a questionnaire filled out by doctors in Ukraine and Germany. A number of n = 100 in each country is seen to be powerful enough for significance of conclusions. Questions will be e.g. First reported case of HIV in individual commemoration. Appraisal of effectiveness of present actions (peer education programs, safer sex campaigns, governmental approaches). Causes of escalation of HIV epidemic in Ukraine (financial lack, stigmata, cultural problem). Own socioeconomic evaluation and their impact on treatment of HIV/AIDS patients. Our expectation is the identification of reasons - besides the general problem of a weak health care system and political insecurity - why the HIV epidemic existing in Ukraine has such a severe course. A.11 (Poster) HIV und AIDS in der Ukraine - neuere Entwicklungen Alberth F. 1 1 Connect plus e.V., Augsburg, Germany Ziele: Informationen über die epidemiolgische Entwicklung in der Ukraine Methodik: Präsentation Ergebnis: In der Ukraine und in der Russische Förderation steigen die Neuinfektionszahlen ständig an. Auch die „Bereinigung“ der Statistik hilft wenig. (Momentan werden in der Statistik des Nationalen Aids-Zentrum nur noch die Menschen mit HIV und Aids erfasst, die sich beim Gesundheitssystem registrieren lassen und Kontakt zu den Kliniken oder Ärzten haben. Die antiretroviralen Medikamente sind vorhanden, erreichen jedoch nicht in ausreichendem Maße die Patienten, die dringend eine Therapie brauchen. Die Entwicklung in einem Hochprävalenzgebiet der Ukraine (Odessa) und in einem Niedrugprävalenzgebiet (Lemberg) werden dargestellt und die Reaktion des Staates und der NGO-Landschaft auf diese Herausforderung aufgezeigt. Verschiedene in- und ausländische Akteure entwickeln auf nationaler und lokaler Ebene Programme. Eine kurze Übersicht stellt den momentanen Stand dar. Schlussfolgerung: Connect plus arbeitet seit 6 Jahren in der Qualifizierung von medizinischem und sozial-psychologischen Fachkräften. Projekte, die auch modellhaft übertragen werden können werden vorgestellt. A.12 (Vortrag) KABaSTI-study results: Self reported incidence of bacterial sexually transmitted infections (STIs) in German men who have sex with men (MSM) - influence of HIV serostatus and sexual risk taking Marcus U. 1 , Schmidt A.J. 1 , Hamouda O. 1 1 Robert Koch-Institut, Infektionsepidemiologie, Berlin, Germany Objectives: An increase of STIs in MSM has been reported from many Western industrialised countries in recent years. Repeated behaviour surveys in MSM have demonstrated increasing numbers of sexual partners and declining use of condoms for anal intercourse. To better understand the reasons for increasing rates of STIs in MSM and to identify potential new approaches to STI prevention, a survey on knowledge, attitudes and behaviour as to STIs (KABaSTI-study) in MSM was conducted in 2006. Methods: Participants were recruited on German internet MSM contact sites (n=5,928) and country-wide through private medical practices (n=723) with a high proportion of MSM clients. 6,833 completed questionnaires were analysed. Sexually transmitted infections diagnosed in the previous 12 months were assessed. Results: From all responding participants (n=4,648), 5% each reported a diagnosis of syphilis or urethral gonorrhoea, and 3,9% a diagnosis of Chlamydia infection. Incidence of these bacterial STIs (bSTI) was significantly higher in HIV positive (HIV+) compared to HIV negative (HIV-) or untested men, as well as in men who reported more than 10 compared to 10 or less partners (OR=4.9; 95%CI:4.0-5.9), and in men who reported 5 or more episodes of unprotected anal intercourse (UAI) compared to less than 5 during the last 12 months (OR=7.3; 95%CI:5.9-9.1). HIV+ men without antiretroviral treatment (ART) reported higher incidences than HIV+ men receiving ART (OR=2.0; 95%CI:1.5-2.7). The highest incidences of bSTIs among HIV+ and HIV- men were reported by participants recruited through a bareback website. After controlling for number of partners and frequency of UAI, HIV+ (OR=2.1; 95%CI:1.3-3.3) and HIV- (OR=2.4; 95%CI:1.5-3.9) men from bareback sites had higher risks of having been diagnosed with bSTIs than men recruited from other sites. Conclusions: Incidence of bSTIs is higher in HIV+ than in HIV- MSM. This can be explained by higher number of partners, more unprotected intercourse, less intention to use condoms for prevention of STIs, and formation of high risk sexual networks in which unprotected sex is common. Receiving ART may not only reduce the risk of further HIV transmission, but also the risk for acquisition of STIs by unknown mechanisms. Study supported by BMG A.13 (Poster) Highly variable use of diagnostic methods for sexually transmitted infections – results of a nationwide survey, Germany 2006 Gilsdorf A. 1 , Hamouda O. 1 , Bremer V. 1 1 Robert Koch-Institut, Abt. für Infektionsepidemiologie, Berlin, Germany Objective: Syphilis and HIV are the only notifiable sexually transmitted infections (STI) in Germany. Further data for STI are collected through a sentinel surveillance system. The use of diagnostic methods with high sensitivity and specificity are needed for high data quality and early detection. We asked sentinel and other physicians about the current use of diagnostic methods for STIs in order to recognise potential problems and provide recommendations. Methods: We performed a nationwide cross-sectional survey among randomly chosen physicians with a specialisation in gynaecology, urology and dermato-venerology (DV) as well as sentinel physicians. We asked physicians about the methods and the type of samples used to diagnose HIV, chlamydia (CT), gonorrhoea (GO) and syphilis (SY) and whether they would perform STI testing in asymptomatic patients. The results were stratified by medical speciality. Results: A total of 691/2228 (31.0%) physicians participated. 80.1% participants offered tests for HIV, 84.0% for CT,
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