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OIPMIV
1 2 1 1 3 3
1
2
3
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OIPM
2007
SA
SA
SA 2 SA
2
SA 2 SA
SA
OIPM
CT
1 2 2 3 4
1
2 3
4
21 X CT
22
1 mm CT
3
10 CT
3
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CT 3D
OIPM
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2008
2009
2010
[
86: 3337 2011]1. 2.
3. 4.
3. 3
OIPM
Organization of the lens elasticity associating with accommodation
in monkey eyes
Mari Hiraoka 1,2,3 , Haruki Senoo 3 , Masahiko Takada 4
1
Koganei Eye Clinic, 2 Lab. Brain Develop, Tokyo Metropolitan Inst. Med. Sci.,
3
Dept. Cell Biol. Morphol, Akita Univ. Grad. Sch. Med., 4 System Neurosci. Sect,
Primate Res. Inst, Kyoto Univ.
To understand the mechanism of accommodation, our dynamic connective tissue
theory revealed the zonule inside of capsule may work for traction of capsule
itself. And present study is conducted to analyze the comprehensive structure of
lens fiber configuration to induce increase of central thickness and decrease of
vertical diameter in primate eyes.
Morphology of zonule, capsule and lens fiber arrangement and tracer uptake
through capsule were examined.
Premature lens had horizontally aligned fiber and vascular net. The most
distinctive feature in mature lens was intracapsular zonular branching in equatorial
and anterior apical regions. Adult lens showed subepithelial elastic lamellae
localized in superficial equatorial and anterior region. In aged lens major internal
structure was horizontally arranged, tightly packed nonelastic fibers.
Lifelong growth of lens fiber causes degenerative deterioration on fiber flexibility
and also capsular responsibility to the zonular active traction. These finding may
support our theory.
OIPM
CCP
50
connecting cilium
CCP1
CCP1
3
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CCP1 TTLL1
CCP1
CCP1
CCP1