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88 117 S G1 DNA S G2 G2 G1 S Microtubule (MT) organization plays a key role in neuronal migration and axon/dendrite formation. Here we monitored the dynamics of centrosome and MT plus ends in neocortical neurons. In multipolar migrating neurons, newly emerging processes formed irrespective of the centrosome localization. The centrosome tended to move toward the dominant growing process. In locomoting neurons, which have a bipolar shape, the centrosome was targeted toward the piadirected leading process. However, the centrosome at the base of the leading process, in front of the nucleus, was occasionally overtaken by the translocating nucleus. When a locomoting neuron formed an axon-like trailing process opposite the direction of migration, the centrosome was located on the other side of the cell. MT growth in the leading processes of bipolar neurons was mostly directed toward the distal tip, while few bidirectional MT plus-end movements were detected in the trailing process. Depletion of gamma-tubulin in these neurons resulted in stacking of migration-defected neurons in the intermediate zone. Interestingly, neurons that managed to migrate into the cortical plate showed striking abnormalities in orientation. S 1,2,3 1 2 3 6 S stathmin 1 1,2,3 4 4 5 2 1,2,3 1 2 3 4 5 PACAP PACAP PACAP KO PACAP α/β tubulin stathmin1 Stathmin1 subgranular zone PACAP KO stathmin1 axon stathmin1 axon stathmin1 axon PACAP stathmin1 axon abnormal arborization stathmin1 adult neurogenesis stathmin1
117 89 S C 1 1 2 1 2 1 DA 5HT 5HT 2C 5HT 2C R 5HT 2C R 5HT 2C R 5HT 2C R 2 5AE RNA 2 C57BL/6J RNA VXV 1.5 C3H/HeJ RNA 5HT 2C R RNA ADAR1/2 5HT 2C R C57BL/6J 5HT 2C R RNA S 1,2 1 1 1 2 G GPCR GPCR GALP WNPW GALP NPW GALP NPW GALP GALP NPW S kisspeptin puberty GPR54 kisspeptin kisspeptin GnRH HPG axis kisspeptin kisspeptinHPG axis Kisspeptin Kisspeptin S POMC
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117 5 100 http://yamanashiko
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Page 46 and 47: 40 117 E L C LC ::OEPM I
Page 48 and 49: 42 117 E L C LC ::OEAM III
Page 50 and 51: 44 117 2OHAMIII2 2OHAMIII3 1
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Page 56 and 57: 50 117 1P073 Makoto Naganuma Acti
Page 58 and 59: 52 117 2P018 Conserved properti
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Page 75 and 76: 117 67 S 1,2 1 1 2 JST S
Page 77 and 78: 117 69 S The role of autophagyrela
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Page 87 and 88: 117 79 S niche DNA endos
Page 89 and 90: 117 81 S GABA GABA Cl KCC2C
Page 91 and 92: 117 83 S By means of retrograd
Page 93 and 94: 117 85 S S
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Page 99 and 100: 117 91 S Focused Ion BeamScanning
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Page 107 and 108: 117 99 OEPMI Singleneuron tracing
Page 109 and 110: 117 101 OFPMII 1 2 3 2
Page 111 and 112: 117 103 OHPM Two immunogenic passe
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Page 117 and 118: 117 109 OGAMII BrdU Labelr
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Page 121 and 122: 117 113 ODPMI Large Maf Large
Page 123 and 124: 117 115 OEPMVII 1 1 2 2
Page 125 and 126: 117 117 OFPMVIII α
Page 127 and 128: 117 119 OHPMIV 1
Page 129 and 130: 117 121 OIPMIV 1 2 1 1
Page 131 and 132: 117 123 P SA 1 2 1 2 Glial
Page 133 and 134: 117 125 P γ 4,52 P
Page 135 and 136: 117 127 P cFos 1 2 1 1
Page 137 and 138: 117 129 P Identification of CSPG c
Page 139 and 140: 117 131 P NOS 1 2 4 4
Page 141 and 142: 117 133 P DPEP 1 2 2 1
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117 139 P Nacholapithecus kerioi
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117 141 P kirrel 1 1 1
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117 143 P prechordal chond
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117 145 P FIB/SEM 1,3 1 2
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117 147 P VIP 12 VIP
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117 149 P Motor protein KIFA is es
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117 151 P parvic
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117 153 P SEM 75 mM KC
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117 155 P mAtgAAcGFP mDFCPmCherry
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117 157 P αMangostin 1 2
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117 159 P 1 1 1 1 2 1
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117 161 P planar cell polarity
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117 163 P The metabolism of choles
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117 165 P 1 1 2 2 1 1
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117 167 P 1 2 1 3 1 1
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117 169 P Agerelated changes in es
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117 173 P Vc Vc M
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192 117 Marson, Lesley Masahiro,
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194 117 1OFPMI2 1OFPM
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