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Linkages with other SIs<br />

SI 7 will make use of high‐potential, stress‐tolerant germplasm developed in SI 4 and SI 5 as parental<br />

materials for introgression of genes affecting pro‐VA content, and will use new tools developed in SI 9,<br />

particularly doubled haploids, to speed line extraction. Rapid‐cycle genomic selection may be potentially<br />

used to speed population improvement for complex quantitative traits, such as kernel micronutrient<br />

concentrations (especially zinc). SI 1 will provide guidance on technology targeting, value chains,<br />

marketing strategies, institutional innovations and policy options for effective technological<br />

dissemination and impacts.<br />

What's new in this initiative?<br />

The role of biofortification as a strategy to combat malnutrition and associated health problems has<br />

recently gained global recognition (Copenhagen Consensus 2008) as one of the five highest priority<br />

investments, based on the costs and benefits of the solutions, to combat the greatest global<br />

challenges.<br />

This Strategic Initiative shall provide technological knowledge and germplasm base to TA4<br />

(Agriculture, Health and Nutrition) which aims to provide multidisciplinary, multi‐institutional and<br />

policy support to achieve greater impacts than ever before through biofortification.<br />

The Initiative shall create strong links between molecular genetics (e.g. allele mining and markerassisted<br />

selection), biochemistry (e.g. high‐throughput phenotyping), nutrition (e.g. factors<br />

influencing bioavailability) and plant breeding, for enhanced effectiveness of maize biofortification<br />

strategy.<br />

Targets and impact estimates<br />

Targeting of this Initiative is based mainly on overlap between percentage of malnourished people in the<br />

target country and the contribution of maize to total daily calorie intake. For pro‐VA maize the primary<br />

target country is Zambia, with secondary emphases on Ethiopia, Angola, Ghana and Nigeria, and spillover<br />

to several countries including India, China, South Africa, Zimbabwe, Haiti and Mexico. For QPM the<br />

primary target countries are Guatemala, El Salvador, Honduras, Nicaragua, Ethiopia, Malawi, Zimbabwe,<br />

Zambia, Uganda, Kenya, Ghana, and Nigeria, with spill‐over benefits to many countries in sub‐Saharan<br />

Africa, Asia and Latin America, including Mali, Benin Republic, India and China.<br />

Development of new nutritionally enhanced cultivars (with 50–100% increase in essential amino acids,<br />

pro‐vitamin A and micronutrient content) and their adoption in target countries in sub‐Saharan Africa,<br />

Asia and LA, will have significant nutritional benefits to at least 100,000 resource‐poor and malnourished<br />

families by 2016, and 200,000 families by 2020 with regard to VA, and millions of consumers with regard<br />

to QPM. This initiative would have potential impact in terms of disability adjusted life years and<br />

enhancing the productivity of malnourished and resource‐poor maize‐based farming communities.<br />

Other issues<br />

Gender<br />

In developing countries, women play major roles in maize production, storage, and processing and food<br />

preparation. An opportunity often missed in strategies for improving under‐nutrition is the<br />

incorporation of a gender perspective. Women are key actors responsible for both household nutrition<br />

and household agriculture in terms of food crops in developing countries. Women’s abilities in this<br />

regard are limited by the larger social construct of roles and responsibilities of women relative to men—<br />

with a power balance that is usually tilted toward men. Gender inequality limits women’s ability to earn<br />

or control income, acquire resources, and make decisions, which in turn limits their ability to ensure<br />

household nutrition and production of nutritious food crops. Although extensive research and training<br />

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