universidade de são paulo - Faculdade de Odontologia - Unesp

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the selectivity of the adsorption process 4,31 . Yildirim et al. (2006) 36 observed that
acrylic resin surfaces modified by plasma treatments adsorbed different amounts
of high molecular weight mucin. Therefore, the composition of the salivary
pellicle may vary among the materials used. As there are only few data in the
literature about the resulting protein concentrations formed on different prosthetic
materials 37 , further studies are necessary to evaluate these differences.
In conclusion, this study demonstrated that different periods of
preconditioning with saliva did not influence the adhesion of Candida albicans to
the denture-base acrylic resin as evaluated by crystal violet staining and XTT
assay. Further, the coefficient of correlation between the results obtained by
crystal violet staining and XTT assay was not significant. Finally, as the current
study was confined only to one denture-base acrylic resin and one strain of
Candida albicans future studies with other Candida species and denture base
materials are warranted. Besides, in addition to the period of preconditioning with
saliva, other experimental conditions, such as number of donors, speed and time
of centrifugation have varied considerably among studies and the influence of
these differences on Candida adhesion to denture materials needs further
investigations.
Acknowledgements
This research was supported by FAPESP (Grant - 2008/05339-8) and
CNPq (Grant - 479895/2009-0).
References