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CHALLENGING THE TREATMENT PARADIGM FOR ADVANCED RENAL CELL CARCINOMA 63. Pantuck AJ, Zisman A, Dorey F, et al. Renal cell carcinoma with retroperitoneal lymph nodes. Impact on survival and benefıts of immunotherapy. Cancer. 2003;97:2995-3002. 64. Pantuck AJ, Zisman A, Dorey F, et al. Renal cell carcinoma with retroperitoneal lymph nodes: role of lymph node dissection. J Urol. 2003;169: 2076-2083. 65. Freedland SJ, Dekernion JB. Role of lymphadenectomy for patients undergoing radical nephrectomy for renal cell carcinoma. Rev Urol. 2003; 5:191-195. 66. Phillips CK, Taneja SS. The role of lymphadenectomy in the surgical management of renal cell carcinoma. Urol Oncol. 2004;22:214- 223. 67. Margulis V, McDonald M, Tamboli P, et al. Predictors of oncological outcome after resection of locally recurrent renal cell carcinoma. J Urol. 2009;181:2044-2051. 68. Tanis PJ, van der Gaag NA, Busch OR, et al. Systematic review of pancreatic surgery for metastatic renal cell carcinoma. Br J Surg. 2009;96:579-592. 69. Bex A, Jonasch E, Kirkali Z, et al. Integrating surgery with targeted therapies for renal cell carcinoma: current evidence and ongoing trials. Eur Urol. 2010;58:819-828. asco.org/edbook | 2015 ASCO EDUCATIONAL BOOK e247
GENITOURINARY CANCER Controversies in the Management of Germ Cell Tumors CHAIR George J. Bosl, MD Memorial Sloan Kettering Cancer Center New York, NY SPEAKERS Alan Horwich, MBBS, MRCP, FRCR, PhD The Institute of Cancer Research, Royal Marsden Hospital Sutton, United Kingdom Lawrence H. Einhorn, MD Indiana University Indianapolis, IN
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AMERICAN SOCIETY OF CLINICAL ONCOLO
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American Society of Clinical Oncolo
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Controversies in Neoadjuvant Therap
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Clinical Trials of Precision Medici
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Managing Ovarian Cancer in the Olde
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Updates in the Multimodality Manage
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PEDIATRIC ONCOLOGY Real-Time Molecu
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2015 ASCO Annual Meeting Disclosure
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2015 Educational Book Expert Panel
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James Marshall, PhD Roswell Park Ca
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2015 Annual Meeting Supporters* MIS
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David Yurman Corporate Allies Conqu
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INVITED ARTICLES This year’s invi
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WONG, CAPASSO, AND ECKHARDT 3 3 sc
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WONG, CAPASSO, AND ECKHARDT terize
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WONG, CAPASSO, AND ECKHARDT for mul
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STEPHEN T. SONIS portantly, patient
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STEPHEN T. SONIS elements of a clus
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STEPHEN T. SONIS Defıning the clin
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STEPHEN T. SONIS predict oral mucos
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HUSSAIN AND DIPAOLA TABLE 1. U.S. F
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HUSSAIN AND DIPAOLA mizing use of p
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INVITED ARTICLES DIAGNOSTICS The Fu
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EDWARD S. KIM TABLE 1. Selected Umb
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EDWARD S. KIM platform that plans t
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INVITED ARTICLES HEAD AND NECK CANC
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GROSS AND COHEN treatments are poor
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GROSS AND COHEN 22. Ratner M. Pharm
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GILBERT ET AL tional scholars, lead
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GILBERT ET AL ment of physician com
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GILBERT ET AL greater understanding
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INVITED ARTICLES GASTROINTESTINAL C
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ENG ET AL colorectal cancer. Indeed
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INVITED ARTICLES BREAST CANCER I Wi
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WILLIAM M. SIKOV gational treatment
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DELUCHE, ONESTI, AND ANDRE Precisio
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DELUCHE, ONESTI, AND ANDRE the path
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DELUCHE, ONESTI, AND ANDRE combine
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SALAMA AND CHMURA Surgery or Ablati
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SALAMA AND CHMURA TABLE 1. Frequenc
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SALAMA AND CHMURA per patient was 8
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SALAMA AND CHMURA 4. Fisher B. Labo
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BREAST CANCER Controversies in Neoa
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WHITE AND DEMICHELE KEY POINTS
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WHITE AND DEMICHELE growing body of
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WHITE AND DEMICHELE signed with app
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BREAST CANCER Individualizing the A
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OLDER WOMEN WITH EARLY-STAGE BREAST
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IMMUNITY IN TRIPLE-NEGATIVE BREAST
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MOLECULAR SUBTYPES AND NEW TARGETS
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ADJUVANT AND NEOADJUVANT THERAPY FO
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CANCER PREVENTION, GENETICS, AND EP
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ADDRESSING BARRIERS TO BREAST CANCE
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DECISION MAKING IN THE CONTEXT OF B
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SCHIFFMAN, FISHER, AND GIBBS econom
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SCHIFFMAN, FISHER, AND GIBBS High-r
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SCHIFFMAN, FISHER, AND GIBBS could
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SCHIFFMAN, FISHER, AND GIBBS due to
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CAN DIET AND LIFESTYLE PREVENT BREA
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REFORMING THE BUY-AND-BILL CHEMOTHE
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CARE DELIVERY AND PRACTICE MANAGEME
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THE PATIENT-CENTERED MEDICAL HOME c
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THE PATIENT-CENTERED MEDICAL HOME F
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THE PATIENT-CENTERED MEDICAL HOME F
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THE PATIENT-CENTERED MEDICAL HOME c
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INTEGRATING ICD-10 IN YOUR PRACTICE
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CENTRAL NERVOUS SYSTEM TUMORS Brain
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AHLUWALIA AND WINKLER TARGETING ANG
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AHLUWALIA AND WINKLER cancer brain
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AHLUWALIA AND WINKLER However, the
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AHLUWALIA AND WINKLER in patients w
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MEHTA AND AHLUWALIA of SRS for brai
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MEHTA AND AHLUWALIA for patients ol
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MEHTA AND AHLUWALIA 14. Atalar B, M
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MAWRIN, CHUNG, AND PREUSSER Biology
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MAWRIN, CHUNG, AND PREUSSER Fibrobl
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MAWRIN, CHUNG, AND PREUSSER grade a
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MAWRIN, CHUNG, AND PREUSSER Disclos
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MAWRIN, CHUNG, AND PREUSSER 72. Sur
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DEVELOPMENTAL THERAPEUTICS AND TRAN
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ESTEVA, MILLER, AND TEICHER TARGETS
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ESTEVA, MILLER, AND TEICHER gle che
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ESTEVA, MILLER, AND TEICHER TABLE 2
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ESTEVA, MILLER, AND TEICHER 21. Ans
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STUART M. LICHTMAN include a Geriat
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STUART M. LICHTMAN an outcome of ca
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BARRIOS, WERUTSKY, AND MARTINEZ-MES
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MANDREKAR, DAHLBERG, AND SIMON FIGU
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MANDREKAR, DAHLBERG, AND SIMON FIGU
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MANDREKAR, DAHLBERG, AND SIMON know
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DIENSTMANN, SALAZAR, AND TABERNERO
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RIMAWI, DE ANGELIS, AND SCHIFF FIGU
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RIMAWI, DE ANGELIS, AND SCHIFF TABL
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RIMAWI, DE ANGELIS, AND SCHIFF tent
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RIMAWI, DE ANGELIS, AND SCHIFF phas
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CHRISTINE M. LOVLY TKIs have been t
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CHRISTINE M. LOVLY EGFR TKIs appear
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CHRISTINE M. LOVLY MAP2K1, which en
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CHRISTINE M. LOVLY patients with ad
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DAMODARAN, BERGER, AND ROYCHOWDHURY
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ZARDAVAS AND PICCART-GEBHART TABLE
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ZARDAVAS AND PICCART-GEBHART TABLE
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ZARDAVAS AND PICCART-GEBHART triple
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ZARDAVAS AND PICCART-GEBHART mutati
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MICHAEL A. POSTOW Managing Immune C
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MICHAEL A. POSTOW diarrhea symptoms
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MICHAEL A. POSTOW tion. One of thes
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MICHAEL A. POSTOW nitis during ipil
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GASTROINTESTINAL (COLORECTAL) CANCE
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PRECISION THERAPY FOR RECTAL CANCER
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PRECISION THERAPY FOR RECTAL CANCER
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GASTROINTESTINAL (COLORECTAL) CANCE
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MARWAN FAKIH was offset by a detrim
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MARWAN FAKIH TABLE 1. Biologicals i
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MARWAN FAKIH TABLE 3. EGFR Targetin
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MARWAN FAKIH TABLE 6. EGFR Targetin
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MARWAN FAKIH 5-fluorouracil (FOLFIR
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PUNT, SIMKENS, AND KOOPMAN 5-FU/LV
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PUNT, SIMKENS, AND KOOPMAN TABLE 1.
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PUNT, SIMKENS, AND KOOPMAN 35. Veno
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CERCEK, CUSACK, AND RYAN Treatment
Page 324 and 325: CERCEK, CUSACK, AND RYAN leagues pe
Page 326 and 327: GASTROINTESTINAL (NONCOLORECTAL) CA
Page 328 and 329: ABOU-ALFA ET AL sess liver function
Page 330 and 331: ABOU-ALFA ET AL tinuing liver injur
Page 332 and 333: ABOU-ALFA ET AL mors including HCC,
Page 334 and 335: ABOU-ALFA ET AL HCC (Anti-Programme
Page 336 and 337: AHN ET AL Making Sense of Current a
Page 338 and 339: AHN ET AL Pancreatic cancer has bee
Page 340 and 341: AHN ET AL Disclosures of Potential
Page 344 and 345: EGIDIO DEL FABBRO tion of precachex
Page 346 and 347: EGIDIO DEL FABBRO FIGURE 3. Mechani
Page 348 and 349: EGIDIO DEL FABBRO II RCT of ghrelin
Page 350 and 351: EGIDIO DEL FABBRO 22. Tan BH, Birds
Page 354 and 355: THE SPECTRUM OF NEUROENDOCRINE TUMO
Page 366 and 367: CHALLENGING THE TREATMENT PARADIGM
Page 376 and 377: STAGE I TESTICULAR GERM CELL CANCER
Page 378 and 379: STAGE I TESTICULAR GERM CELL CANCER
Page 380 and 381: GERM CELL TUMORS: LOOKING TO THE FU
Page 386 and 387: SALVAGE CHEMOTHERAPY Salvage Therap
Page 388 and 389: SALVAGE CHEMOTHERAPY References 1.
Page 390 and 391: EARLY CHEMOTHERAPY IN MEN WITH META
Page 398 and 399: RADIUM 223 AND METASTATIC CASTRATIO
Page 400 and 401: RADIUM 223 AND METASTATIC CASTRATIO
Page 402 and 403: IMMUNOTHERAPY FOR PROSTATE TUMORS I
Page 404 and 405: IMMUNOTHERAPY FOR PROSTATE TUMORS F
Page 406 and 407: IMMUNOTHERAPY FOR PROSTATE TUMORS T
Page 408 and 409: IMMUNOTHERAPY FOR PROSTATE TUMORS F
Page 410 and 411: IMMUNOTHERAPY FOR PROSTATE TUMORS a
Page 412 and 413: EVOLVING IMMUNOTHERAPY STRATEGIES I
Page 418 and 419: NOVEL IMMUNOTHERAPY AGENTS IN METAS
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NOVEL IMMUNOTHERAPY AGENTS IN METAS
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PROMISING STRATEGIES IN BLADDER CAN
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GYNECOLOGIC CANCER Cervical Cancer
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MACKAY, WENZEL, AND MILESHKIN In th
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MACKAY, WENZEL, AND MILESHKIN admin
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MACKAY, WENZEL, AND MILESHKIN TABLE
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MACKAY, WENZEL, AND MILESHKIN ing s
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MACKAY, WENZEL, AND MILESHKIN 59. F
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GYNECOLOGIC CANCER Managing Ovarian
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DUSKA, TEW, AND MOORE KEY POINTS A
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DUSKA, TEW, AND MOORE FIGURE 2. Sur
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DUSKA, TEW, AND MOORE FIGURE 3. Che
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DUSKA, TEW, AND MOORE FIGURE 4. Ger
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DUSKA, TEW, AND MOORE 10. Griffıth
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GYNECOLOGIC CANCER Treatment of the
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CHEMOTHERAPY FOR PATIENTS WITH BMOC
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PROGRESS IN HEAD AND NECK SQUAMOUS
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HEAD AND NECK CANCER PI3-Kinase: Ge
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ISAACSSON VELHO, CASTRO JR, AND CHU
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SHARON H. GIORDANO Comparative Effe
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SHARON H. GIORDANO measured confoun
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SHARON H. GIORDANO These databases
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HEALTH SERVICES RESEARCH AND QUALIT
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INDUSTRY AND ONCOLOGY KEY POINTS F
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INDUSTRY AND ONCOLOGY has been “l
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INDUSTRY AND ONCOLOGY by (covered)
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INDUSTRY AND ONCOLOGY 42. World Hea
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CANCER CARE QUALITY: CURRENT STATE
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MANAGING OLDER PATIENTS WITH ALL Th
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MANAGING OLDER PATIENTS WITH ALL TA
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MANAGING OLDER PATIENTS WITH ALL FI
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MANAGING OLDER PATIENTS WITH ALL FI
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MANAGING OLDER PATIENTS WITH ALL ra
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TREATMENT OF PHILADELPHIA CHROMOSOM
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CD19 CAR THERAPY FOR ALL FIGURE 1.
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CD19 CAR THERAPY FOR ALL 5. Zhou G,
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NEW TARGETED THERAPIES FOR iNHL New
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NEW TARGETED THERAPIES FOR iNHL TAB
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NEW TARGETED THERAPIES FOR iNHL a P
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HEMATOPOIETIC CELL TRANSPLANTATION
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LEUKEMIA, MYELODYSPLASIA, AND TRANS
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MICHAEL W. DEININGER TABLE 1. Defin
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MICHAEL W. DEININGER the ATP-bindin
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MICHAEL W. DEININGER broad range ef
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MICHAEL W. DEININGER 30. Hughes T,
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PEMMARAJU AND MOLITERNO TABLE 1. Ac
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PEMMARAJU AND MOLITERNO drome (BCS)
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PEMMARAJU AND MOLITERNO 13. Xing S,
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THERAPIES AND INDICATIONS FOR PH-NE
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Page 566 and 567:
LEUKEMIA, MYELODYSPLASIA, AND TRANS
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RECENT UPDATES IN MDS AND MDS/MPNS
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LUNG CANCER Beyond Second-Line Trea
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BEYOND SECOND-LINE TREATMENT FOR LU
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BEYOND SECOND-LINE TREATMENT FOR LU
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LUNG CANCER New Therapies for Histo
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GERBER, PAIK, AND DOWLATI a tumor t
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GERBER, PAIK, AND DOWLATI squamous
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GERBER, PAIK, AND DOWLATI FIGURE 2.
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GERBER, PAIK, AND DOWLATI TABLE 1.
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GERBER, PAIK, AND DOWLATI gression
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GERBER, PAIK, AND DOWLATI Disclosur
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GERBER, PAIK, AND DOWLATI enzyme in
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GERBER, PAIK, AND DOWLATI receptor
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LILENBAUM, LEIGHL, AND NEUBAUER Exp
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LILENBAUM, LEIGHL, AND NEUBAUER tha
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LILENBAUM, LEIGHL, AND NEUBAUER Ref
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BERNARDO H.L. GOULART The Value of
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BERNARDO H.L. GOULART TABLE 1. Expe
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BERNARDO H.L. GOULART every 6 month
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BERNARDO H.L. GOULART lung-cancer/l
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LUNG CANCER Updates in the Multimod
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WOODARD AND JABLONS section, becaus
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WOODARD AND JABLONS mediastinum is
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WOODARD AND JABLONS FIGURE 1. Molec
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NASSER HANNA Current Standards and
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NASSER HANNA At the 2014 ASCO Annua
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NASSER HANNA culty of this task. Va
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LYMPHOMA AND PLASMA CELL DISORDERS
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NOWAKOWSKI AND CZUCZMAN sociated wi
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NOWAKOWSKI AND CZUCZMAN trial is in
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NOWAKOWSKI AND CZUCZMAN TABLE 2. DH
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NOWAKOWSKI AND CZUCZMAN 15. Aragon-
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DAVID W. SCOTT Cell-of-Origin in Di
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DAVID W. SCOTT FIGURE 1. The Origin
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DAVID W. SCOTT FIGURE 2. Immunohist
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DAVID W. SCOTT FIGURE 3. The Lymph2
Page 652 and 653:
DAVID W. SCOTT 10. Shaffer AL 3rd,
Page 654 and 655:
CHEAH, OKI, AND FANALE Novel Treatm
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CHEAH, OKI, AND FANALE an ongoing G
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CHEAH, OKI, AND FANALE a similar me
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CHEAH, OKI, AND FANALE TABLE 3. Sel
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CHEAH, OKI, AND FANALE eral T cell
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CHEAH, OKI, AND FANALE 77. Cairns R
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STEPHEN ANSELL associated with pati
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STEPHEN ANSELL Disclosures of Poten
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MATEOS AND SAN MIGUEL Smoldering Mu
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MATEOS AND SAN MIGUEL years. This f
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MATEOS AND SAN MIGUEL previously me
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MATEOS AND SAN MIGUEL TABLE 2. Risk
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MATEOS AND SAN MIGUEL 30. Rajkumar
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BHUTANI, LANDGREN, AND USMANI of th
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BHUTANI, LANDGREN, AND USMANI bette
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BHUTANI, LANDGREN, AND USMANI fıne
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BHUTANI, LANDGREN, AND USMANI FIGUR
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BHUTANI, LANDGREN, AND USMANI 15. K
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MOREAU AND TOUZEAU Multiple Myeloma
Page 692 and 693:
MOREAU AND TOUZEAU other effıcacy
Page 694 and 695:
MOREAU AND TOUZEAU was able to indu
Page 696 and 697:
MOREAU AND TOUZEAU Group consensus
Page 698 and 699:
LYMPHOMA AND PLASMA CELL DISORDERS
Page 700 and 701:
MANAGEMENT OF CLL Up-Front Manageme
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MANAGEMENT OF CLL than 17p-/TP53mut
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MANAGEMENT OF CLL could be associat
Page 706 and 707:
MANAGEMENT OF CLL tion by nonmalign
Page 708 and 709:
MANAGEMENT OF CLL fludarabine and c
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MANAGEMENT OF CLL lymphocytic leuke
Page 712 and 713:
PROGNOSTIC FACTORS AND ADJUVANT RAD
Page 714 and 715:
Page 716 and 717:
Page 718 and 719:
MERKEL CELL CARCINOMA Merkel Cell C
Page 720 and 721:
MERKEL CELL CARCINOMA tions in PIK3
Page 722 and 723:
MERKEL CELL CARCINOMA treating MCC
Page 724 and 725:
MERKEL CELL CARCINOMA 32. Leonard J
Page 726 and 727:
MELANOMA/SKIN CANCERS Locoregional
Page 728 and 729:
PERFUSION AND INFUSION IN THE ERA O
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Page 732 and 733:
Page 734 and 735:
NEOADJUVANT THERAPY OF MELANOMA Neo
Page 736 and 737:
NEOADJUVANT THERAPY OF MELANOMA TAB
Page 738 and 739:
NEOADJUVANT THERAPY OF MELANOMA ity
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NEOADJUVANT THERAPY OF MELANOMA 4.
Page 742 and 743:
MELANOMA/SKIN CANCERS Targeted Mole
Page 744 and 745:
SULLIVAN ET AL FIGURE 1. Relevant S
Page 746 and 747:
SULLIVAN ET AL Resistance to BRAF i
Page 748 and 749:
SULLIVAN ET AL TABLE 1. Clinical Tr
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SULLIVAN ET AL 17. Halait H, Demart
Page 752 and 753:
SULLIVAN ET AL NRAS-mutant melanoma
Page 754 and 755:
KLEPIN, RODIN, AND HURRIA Treating
Page 756 and 757:
KLEPIN, RODIN, AND HURRIA plication
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KLEPIN, RODIN, AND HURRIA plan was
Page 760 and 761:
KLEPIN, RODIN, AND HURRIA patient-s
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KLEPIN, RODIN, AND HURRIA 62. Blanc
Page 764 and 765:
PERIPHERAL NEUROTOXICITY IN CANCER
Page 766 and 767:
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Page 770 and 771:
Page 772 and 773:
PARTRIDGE, JACOBSEN, AND ANDERSEN C
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PARTRIDGE, JACOBSEN, AND ANDERSEN c
Page 776 and 777:
PARTRIDGE, JACOBSEN, AND ANDERSEN w
Page 778 and 779:
PARTRIDGE, JACOBSEN, AND ANDERSEN v
Page 780 and 781:
LESLIE R. SCHOVER Sexual Healing in
Page 782 and 783:
LESLIE R. SCHOVER tinuous ADT in pr
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LESLIE R. SCHOVER 12. Potosky AL, H
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CATHERINE H. VAN POZNAK TABLE 1. Wo
Page 788 and 789:
CATHERINE H. VAN POZNAK (tamoxifen,
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CATHERINE H. VAN POZNAK TABLE 3. FD
Page 792 and 793:
CATHERINE H. VAN POZNAK premenopaus
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SHARI GOLDFARB KEY POINTS Brea
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SHARI GOLDFARB and friction with va
Page 798 and 799:
SHARI GOLDFARB importance both duri
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PATIENT AND SURVIVOR CARE Moving Su
Page 802 and 803:
MAYER ET AL TABLE 1. Quality Metric
Page 804 and 805:
MAYER ET AL to enhance the quality
Page 806 and 807:
MAYER ET AL FIGURE 2. (A) Infertili
Page 808 and 809:
MAYER ET AL efıcial suggests that
Page 810 and 811:
PATIENT AND SURVIVOR CARE The Chall
Page 812 and 813:
BRUERA AND PAICE Choice of Opioid a
Page 814 and 815:
BRUERA AND PAICE toxicity and proce
Page 816 and 817:
BRUERA AND PAICE effective. Basic s
Page 818 and 819:
PEDIATRIC ONCOLOGY Real-Time Molecu
Page 820 and 821:
CARROLL, RAETZ, AND MEYER KEY POINT
Page 822 and 823:
CARROLL, RAETZ, AND MEYER most are
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CARROLL, RAETZ, AND MEYER markers a
Page 826 and 827:
PEDIATRIC ONCOLOGY Translating Surv
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REDUCING THE BURDEN OF LATE EFFECTS
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Page 832 and 833:
Page 834 and 835:
Page 836 and 837:
PROFESSIONAL DEVELOPMENT The Challe
Page 838 and 839:
ADVANCES IN WEBSITE INFORMATION RES
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Page 842 and 843:
Page 844 and 845:
Page 846 and 847:
COMMUNICATION AND TECHNOLOGY: IT’
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Page 850 and 851:
Page 852 and 853:
PATIENT-REPORTED OUTCOMES IN ONCOLO
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PATIENT-REPORTED OUTCOMES IN ONCOLO
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PROFESSIONAL DEVELOPMENT Trends, An
Page 858 and 859:
CLINICAL ONCOLOGY PRACTICE 2015 FIG
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CLINICAL ONCOLOGY PRACTICE 2015 (6.
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CLINICAL ONCOLOGY PRACTICE 2015 Pro
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ADJUVANT/NEOADJUVANT MEDICAL THERAP
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Page 868 and 869:
Page 870 and 871:
INDICATIONS FOR ADJUVANT RADIATION
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Page 874 and 875:
Page 876 and 877:
Page 878 and 879:
SARCOMA Latest Advances in Systemic
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SYSTEMIC THERAPY FOR OSTEOSARCOMA A
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SYSTEMIC THERAPY FOR OSTEOSARCOMA A
Page 884 and 885:
RETHINKING TREATMENT FOR CHONDROSAR
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Page 888 and 889:
Page 890 and 891:
Page 892 and 893:
BONE SARCOMAS IN ADULTS local disea
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BONE SARCOMAS IN ADULTS structure a
Page 896 and 897:
SARCOMA Well-Differentiated and Ded
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ABBAS MANJI ET AL ticular region. 7
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ABBAS MANJI ET AL MYXOID (ROUND CEL
Page 902 and 903:
ABBAS MANJI ET AL versus doxorubici
Page 904 and 905:
SHLUSH AND HERSHKOVITZ Clonal Evolu
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SHLUSH AND HERSHKOVITZ FIGURE 1. Ti
Page 908 and 909:
TUMOR BIOLOGY New Strategies to Und
Page 910 and 911:
KNAPP, DHAWAN, AND OSTRANDER in dog
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KNAPP, DHAWAN, AND OSTRANDER TABLE
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KNAPP, DHAWAN, AND OSTRANDER 14. Fe
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SOURBIER, SRINIVASAN, AND LINEHAN M
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SOURBIER, SRINIVASAN, AND LINEHAN F
Page 920 and 921:
SOURBIER, SRINIVASAN, AND LINEHAN T
Page 922:
Author Index Abbas Manji, Gulam ...
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