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PARTRIDGE, JACOBSEN, AND ANDERSEN worries about a range of other noncancer topics and areas of his or her life. Follow-up assessment. The assessment should identify signs and symptoms of anxiety (e.g., panic attacks, trembling, sweating, tachypnea, tachycardia, palpitations, sweaty palms), severity of symptoms, possible stressors (e.g., impaired daily living), risk factors, and times of vulnerability and should also explore underlying problems or causes. If a patient has severe symptoms of anxiety following the further assessment, when possible, confırm an anxiety disorder diagnosis before initiating any treatment options (e.g., DSM-5, which may require making a referral). Treatment for anxiety disorders. For a patient with moderate anxiety, the primary oncology team may choose to manage the concerns using typical supportive care management. In addition, the team can use a stepped care model to tailor any additional intervention recommendations based on variables such as the following: • Current symptomatology level and presence or absence of DSM-5 diagnoses. • Level of functional impairment in major life areas. • Presence or absence of risk factors. • Chronicity of GAD and response to previous treatments, if any. • Patient preference. If anxiolytic therapy is used, patients should be informed of the side effect profıles of the medications, tolerability of treatment (including the potential for interaction with other current medications), response to prior treatment, and patient preference. Patients should be warned of any potential harm or adverse effects—particularly about the long-term use of benzodiazepines in the treatment of anxiety. These medications carry an increased risk of abuse and dependence and are associated with side effects including cognitive impairment. As a consequence, use of these medications should be time limited in accordance with established psychiatric guidelines. 41 Follow-up and reassessment. Because cautiousness and a tendency to avoid threatening stimuli are cardinal features of anxiety pathology, persons with symptoms of anxiety commonly do not follow through on referrals or treatment recommendations. With this in mind, the mental health professional or other member of the clinical team managing the patient’s anxiety should assess the following on a monthly basis or until symptoms have subsided: • Follow through and compliance with individual or group psychologic or psychosocial referrals, as well as satisfaction with the treatment. • Compliance with and pharmacologic treatment, patient’s concerns about side effects, and satisfaction with the symptom relief provided by the treatment. 2,34,42 If medications are used, consider tapering if symptoms are under control and if the primary environmental sources of anxiety are no longer present. Longer periods of tapering are often necessary with benzodiazepines, particularly with potent or rapidly eliminated medications. If compliance is poor, assess and construct a plan to circumvent obstacles to compliance, or discuss alternative interventions that present fewer obstacles. After 8 weeks of treatment, if symptom reduction and satisfaction with treatment are poor despite good compliance, alter the treatment course. SUMMARY OF ANXIETY AND DEPRESSION GUIDELINES As noted in the 2008 Institute of Medicine report, Cancer Care for the Whole Patient: Meeting Psychosocial Health Needs, and confırmed in a recent report, 43 the psychologic needs of patients with cancer are not being addressed, posing a serious problem for U.S. health care. If psychologic needs are not addressed, regardless of when they arise, they then predict later stress and anxiety, 44,45 depressive symptoms, 46 low quality of life, 47 and increased side effects with treatment and more physical symptoms. 48-51 Alternatively, treatment for either anxiety or depression can successfully address issues such as these 31,52 and has the potential to reduce the risk of recurrence 53 or cancer death. 48-50,54 Overall, mood disorders are associated with lower quality of life and soaring health care costs. 55,56 Patients with cancer who are depressed worry about their disease (70%), relationships with friends (77%), the well-being of family members (74%), and fınances (63%), 57 and the sequelae of this includes more symptom distress 58-60 and maladaptive coping, 61 among others. Depression in particular is associated with heightened risk for premature mortality (recurrence risk 1.22–1.39) and cancer death (recurrence risk 1.18). 50,62 Two studies have now documented increased rates of suicide among populations of long-term survivors of breast and testicular cancer. 63,64 Anxiety is the most common mental health issue for longterm cancer survivors. 65 Heightened anxiety is associated with increased side effects and symptoms 66 and poorer physical functioning. 67 Worry, the hallmark of GAD, can be multifocal 68 with content shifting over time from treatment concerns to physical symptoms and limitations. 69 Be it stress, anxiety, or worry, all are related to important neuroendocrine changes, 70 which may account, in part, for the poorer survival among patients with cancer who have heightened stress. 71 The majority of patients with cancer do well, manifesting remarkable resilience at diagnosis, treatment, and thereafter. Regardless of the timing and circumstances by which any psychiatric comorbidity may arise, patients can experience enormous emotional, interpersonal, and fınancial costs, and providers and the health care system alike can encounter economic consequences when depressive and anxiety disorders are not treated. Screening and early, effıcacious treatment for those manifesting signifıcant symptoms of anxiety or depression holds the potential to reduce the human cost of cancer, not only for patients and survivors but also for those who care for and about them. 192 2015 ASCO EDUCATIONAL BOOK | asco.org/edbook
STANDARDIZING CARE FOR ADULT CANCER SURVIVORS Disclosures of Potential Conflicts of Interest Relationships are considered self-held and compensated unless otherwise noted. Relationships marked “L” indicate leadership positions. Relationships marked “I” are those held by an immediate family member; those marked “B” are held by the author and an immediate family member. Institutional relationships are marked “Inst.” Relationships marked “U” are uncompensated. Employment: None. Leadership Position: None. Stock or Other Ownership Interests: None. Honoraria: None. Consulting or Advisory Role: Paul B. Jacobsen, Onyx, Philips Healthcare. Speakers’ Bureau: None. Research Funding: Paul B. Jacobsen, On Q Health, Pfizer. Patents, Royalties, or Other Intellectual Property: None. Expert Testimony: None. Travel, Accommodations, Expenses: Paul B. Jacobsen, Onyx. Other Relationships: None. References 1. DeSantis CE, Lin CC, Mariotto AB, et al. Cancer treatment and survivorship statistics, 2014. CA Cancer J Clin. 2014;64:252-271. 2. Institute of Medicine and National Research Council of the National Academies. From Cancer Patient to Cancer Survivor: Lost in Transition, in Hewitt M, Greenfıeld S, Stovall E (eds). Washington, DC: The National Academies; 2006. 3. Rechis R, Beckford EB, Arvey SR, et al. The essential elements of survivorship care:aLIVESTRONGbrief.Austin,TX.LanceArmstrongFoundation (now the Livestrong Foundation); 2011. http://www.livestrong.org/pdfs/ 3-0/EssentialElementsBrief. Accessed February 22, 2015. 4. Salz T, Oeffınger KC, McCabe MS, et al. Survivorship care plans in research and practice. CA Cancer J Clin. 2012;62:101-117. 5. Salz T, McCabe MS, Onstad EE, et al. Survivorship care plans: is there buy-in from community oncology providers? Cancer. 2014;120:722- 730. 6. Coyle D, Grunfeld E, Coyle K, et al. Cost effectiveness of a survivorship care plan for breast cancer survivors. J Oncol Pract. 2014;10:e86-e92. 7. Henry NL, Hayes DF, Ramsey SD, et al. Promoting quality and evidence-based care in early-stage breast cancer follow-up. J Natl Cancer Inst. 2014;106:dju034. 8. Earle CC, Ganz PA. Cancer survivorship care: don’t let the perfect be the enemy of the good. J Clin Oncol. 2012;30:3764-3768. 9. McCabe MS, Partridge AH, Grunfeld E, et al. Risk-based health care, the cancer survivor, the oncologist, and the primary care physician. Semin Oncol. 2013;40:804-812. 10. McCabe MS, Bhatia S, Oeffınger KC, et al. American Society of Clinical Oncology statement: achieving high-quality cancer survivorship care. J Clin Oncol. 2013;31:631-640. 11. Reilly CM, Bruner DW, Mitchell SA, et al. A literature synthesis of symptom prevalence and severity in persons receiving active cancer treatment. Support Care Cancer. 2013;21:1525-1550. 12. Bower JE, Ganz PA, Desmond KA, et al. Fatigue in breast cancer survivors: occurrence, correlates and impact on quality of life. J Clin Oncol. 2000;18:743-753. 13. Bower JE, Bak K, Berger A, et al. Screening, assessment, and management of fatigue in adult survivors of cancer: an American Society of Clinical Oncology clinical practice guideline adaptation. J Clin Oncol. 2014;32:1840-1850. 14. Howell D, Keller-Olaman S, Oliver TK, et al. A pan-Canadian practice guideline and algorithm: screening, assessment, and supportive care of adults with cancer-related fatigue. Curr Oncol. 2013;20:e233-e246. 15. Mitchell SA, Beck SL, Hood LE, et al. Putting evidence into practice: evidence-based interventions for fatigue during and following cancer and its treatment. Clin J Oncol Nurs. 2007;11:99-113. 16. National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Cancer-Related Fatigue (version 2. 2015). http://www. nccn.org/professionals/physician_gls/pdf/fatigue.pdf. Accessed March 21, 2015. 17. National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Cancer-Related Fatigue (version 2. 2015). http://www. nccn.org/professionals/physician_gls/pdf/fatigue.pdf. Accessed March 21, 2015. 18. National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Survivorship (version 2. 2014). http://www. nccn.org/professionals/physician_gls/pdf/survivorship.pdf. Accessed March 21, 2015. 19. Mitchell SA, Hoffman AJ, Clark JC, et al. Putting evidence into practice: an update of evidence-based interventions for cancer-related fatigue during and following treatment. Clin J Oncol Nurs. 2014;18:38-58. 20. Dulko D, Pace C, Dittus K, et al. Barriers and facilitators to implementing cancer survivorship care plans. Oncol Nurs Forum. 2013;40:575-580. 21. American Society of Clinical Oncology. ASCO University http:// www.university.asco.org. Accessed February 22, 2015. 22. Abernethy AP, Herndon JE, Wheeler JL, et al. Feasibility and acceptability to patients of a longitudinal system for evaluating cancer-related symptoms and quality of life: pilot study of an e/tablet data-collection system in academic oncology. J Pain Symptom Manage. 2009;37:1027- 1038. 23. Yun YH, Lee KS, Kim Y-W, et al. Web-based tailored education program for disease-free cancer survivors with cancer-related fatigue: a randomized controlled trial. J Clin Oncol. 2012;30:1296-1303. 24. Howell D, Keller-Olaman S, Oliver T, et al. A Pan-Canadian Practice Guideline: Screening, Assessment and Care of Psychosocial Distress (Depression, Anxiety) in Adults with Cancer. Canadian Partnership Against Cancer (Cancer Journey Action Group) and the Canadian Association of Psychosocial Oncology. http://www.capo.ca/pdf/ENGLISH_ Depression_Anxiety_Guidelines_for_Posting_Sept2011.pdf. 2010. Accessed February 22, 2015. 25. Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16:606-613. 26. Arroll B, Goodyear-Smith F, Crengle S, et al. Validation of PHQ-2 and PHQ-9 to screen for major depression in the primary care population. Ann Fam Med. 2010;8:348-353. 27. Manea L, Gilbody S, McMillan D. Optimal cut-off score for diagnosing depression with the Patient Health Questionnaire (PHQ-9): a metaanalysis. CMAJ. 2012;184:E191-E196. 28. Akechi T, Okuyama T, Onishi J, et al. Psychotherapy for depression among incurable cancer patients. Cochrane Database Syst Rev. 2008; CD005537. 29. Brown JC, Huedo-Medina TB, Pescatello LS, et al. The effıcacy of exercise in reducing depressive symptoms among cancer survivors: a metaanalysis. PLoS One. 2012;7:e30955. 30. Duijts SF, Faber MM, Oldenburg HS, et al. Effectiveness of behavioral techniques and physical exercise on psychosocial functioning and health-related quality of life in breast cancer patients and survivors-a meta-analysis. Psychooncology. 2011;20:115-126. 31. Faller H, Schuler M, Richard M, et al. Effects of psycho-oncologic inter- asco.org/edbook | 2015 ASCO EDUCATIONAL BOOK 193
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AMERICAN SOCIETY OF CLINICAL ONCOLO
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American Society of Clinical Oncolo
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Controversies in Neoadjuvant Therap
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Clinical Trials of Precision Medici
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Managing Ovarian Cancer in the Olde
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PEDIATRIC ONCOLOGY Real-Time Molecu
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2015 ASCO Annual Meeting Disclosure
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2015 Educational Book Expert Panel
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James Marshall, PhD Roswell Park Ca
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2015 Annual Meeting Supporters* MIS
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David Yurman Corporate Allies Conqu
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INVITED ARTICLES This year’s invi
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ENG ET AL colorectal cancer. Indeed
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WILLIAM M. SIKOV gational treatment
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CANCER PREVENTION, GENETICS, AND EP
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ADDRESSING BARRIERS TO BREAST CANCE
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DECISION MAKING IN THE CONTEXT OF B
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REFORMING THE BUY-AND-BILL CHEMOTHE
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CARE DELIVERY AND PRACTICE MANAGEME
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MICHAEL A. POSTOW Managing Immune C
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PRECISION THERAPY FOR RECTAL CANCER
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PRECISION THERAPY FOR RECTAL CANCER
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ABOU-ALFA ET AL HCC (Anti-Programme
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AHN ET AL Pancreatic cancer has bee
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HEALTH SERVICES RESEARCH AND QUALIT
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INDUSTRY AND ONCOLOGY KEY POINTS F
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CANCER CARE QUALITY: CURRENT STATE
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TREATMENT OF PHILADELPHIA CHROMOSOM
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BEYOND SECOND-LINE TREATMENT FOR LU
Page 586 and 587:
BEYOND SECOND-LINE TREATMENT FOR LU
Page 588 and 589:
LUNG CANCER New Therapies for Histo
Page 590 and 591:
GERBER, PAIK, AND DOWLATI a tumor t
Page 592 and 593:
GERBER, PAIK, AND DOWLATI squamous
Page 594 and 595:
GERBER, PAIK, AND DOWLATI FIGURE 2.
Page 596 and 597:
GERBER, PAIK, AND DOWLATI TABLE 1.
Page 598 and 599:
GERBER, PAIK, AND DOWLATI gression
Page 600 and 601:
GERBER, PAIK, AND DOWLATI Disclosur
Page 602 and 603:
GERBER, PAIK, AND DOWLATI enzyme in
Page 604 and 605:
GERBER, PAIK, AND DOWLATI receptor
Page 606 and 607:
LILENBAUM, LEIGHL, AND NEUBAUER Exp
Page 608 and 609:
LILENBAUM, LEIGHL, AND NEUBAUER tha
Page 610 and 611:
LILENBAUM, LEIGHL, AND NEUBAUER Ref
Page 612 and 613:
BERNARDO H.L. GOULART The Value of
Page 614 and 615:
BERNARDO H.L. GOULART TABLE 1. Expe
Page 616 and 617:
BERNARDO H.L. GOULART every 6 month
Page 618 and 619:
BERNARDO H.L. GOULART lung-cancer/l
Page 620 and 621:
LUNG CANCER Updates in the Multimod
Page 622 and 623:
WOODARD AND JABLONS section, becaus
Page 624 and 625:
WOODARD AND JABLONS mediastinum is
Page 626 and 627:
WOODARD AND JABLONS FIGURE 1. Molec
Page 628 and 629:
NASSER HANNA Current Standards and
Page 630 and 631:
NASSER HANNA At the 2014 ASCO Annua
Page 632 and 633:
NASSER HANNA culty of this task. Va
Page 634 and 635:
LYMPHOMA AND PLASMA CELL DISORDERS
Page 636 and 637:
NOWAKOWSKI AND CZUCZMAN sociated wi
Page 638 and 639:
NOWAKOWSKI AND CZUCZMAN trial is in
Page 640 and 641:
NOWAKOWSKI AND CZUCZMAN TABLE 2. DH
Page 642 and 643:
NOWAKOWSKI AND CZUCZMAN 15. Aragon-
Page 644 and 645:
DAVID W. SCOTT Cell-of-Origin in Di
Page 646 and 647:
DAVID W. SCOTT FIGURE 1. The Origin
Page 648 and 649:
DAVID W. SCOTT FIGURE 2. Immunohist
Page 650 and 651:
DAVID W. SCOTT FIGURE 3. The Lymph2
Page 652 and 653:
DAVID W. SCOTT 10. Shaffer AL 3rd,
Page 654 and 655:
CHEAH, OKI, AND FANALE Novel Treatm
Page 656 and 657:
CHEAH, OKI, AND FANALE an ongoing G
Page 658 and 659:
CHEAH, OKI, AND FANALE a similar me
Page 660 and 661:
CHEAH, OKI, AND FANALE TABLE 3. Sel
Page 662 and 663:
CHEAH, OKI, AND FANALE eral T cell
Page 664 and 665:
CHEAH, OKI, AND FANALE 77. Cairns R
Page 666 and 667:
STEPHEN ANSELL associated with pati
Page 668 and 669:
STEPHEN ANSELL Disclosures of Poten
Page 670 and 671:
MATEOS AND SAN MIGUEL Smoldering Mu
Page 672 and 673:
MATEOS AND SAN MIGUEL years. This f
Page 674 and 675:
MATEOS AND SAN MIGUEL previously me
Page 676 and 677:
MATEOS AND SAN MIGUEL TABLE 2. Risk
Page 678 and 679:
MATEOS AND SAN MIGUEL 30. Rajkumar
Page 680 and 681:
BHUTANI, LANDGREN, AND USMANI of th
Page 682 and 683:
BHUTANI, LANDGREN, AND USMANI bette
Page 684 and 685:
BHUTANI, LANDGREN, AND USMANI fıne
Page 686 and 687:
BHUTANI, LANDGREN, AND USMANI FIGUR
Page 688 and 689:
BHUTANI, LANDGREN, AND USMANI 15. K
Page 690 and 691:
MOREAU AND TOUZEAU Multiple Myeloma
Page 692 and 693:
MOREAU AND TOUZEAU other effıcacy
Page 694 and 695:
MOREAU AND TOUZEAU was able to indu
Page 696 and 697:
MOREAU AND TOUZEAU Group consensus
Page 698 and 699:
LYMPHOMA AND PLASMA CELL DISORDERS
Page 700 and 701:
MANAGEMENT OF CLL Up-Front Manageme
Page 702 and 703:
MANAGEMENT OF CLL than 17p-/TP53mut
Page 704 and 705:
MANAGEMENT OF CLL could be associat
Page 706 and 707:
MANAGEMENT OF CLL tion by nonmalign
Page 708 and 709:
MANAGEMENT OF CLL fludarabine and c
Page 710 and 711:
MANAGEMENT OF CLL lymphocytic leuke
Page 712 and 713:
PROGNOSTIC FACTORS AND ADJUVANT RAD
Page 714 and 715:
Page 716 and 717:
Page 718 and 719:
MERKEL CELL CARCINOMA Merkel Cell C
Page 720 and 721:
MERKEL CELL CARCINOMA tions in PIK3
Page 722 and 723:
MERKEL CELL CARCINOMA treating MCC
Page 724 and 725:
MERKEL CELL CARCINOMA 32. Leonard J
Page 726 and 727: MELANOMA/SKIN CANCERS Locoregional
Page 728 and 729: PERFUSION AND INFUSION IN THE ERA O
Page 734 and 735: NEOADJUVANT THERAPY OF MELANOMA Neo
Page 736 and 737: NEOADJUVANT THERAPY OF MELANOMA TAB
Page 738 and 739: NEOADJUVANT THERAPY OF MELANOMA ity
Page 740 and 741: NEOADJUVANT THERAPY OF MELANOMA 4.
Page 742 and 743: MELANOMA/SKIN CANCERS Targeted Mole
Page 744 and 745: SULLIVAN ET AL FIGURE 1. Relevant S
Page 746 and 747: SULLIVAN ET AL Resistance to BRAF i
Page 748 and 749: SULLIVAN ET AL TABLE 1. Clinical Tr
Page 750 and 751: SULLIVAN ET AL 17. Halait H, Demart
Page 752 and 753: SULLIVAN ET AL NRAS-mutant melanoma
Page 754 and 755: KLEPIN, RODIN, AND HURRIA Treating
Page 756 and 757: KLEPIN, RODIN, AND HURRIA plication
Page 758 and 759: KLEPIN, RODIN, AND HURRIA plan was
Page 760 and 761: KLEPIN, RODIN, AND HURRIA patient-s
Page 762 and 763: KLEPIN, RODIN, AND HURRIA 62. Blanc
Page 764 and 765: PERIPHERAL NEUROTOXICITY IN CANCER
Page 772 and 773: PARTRIDGE, JACOBSEN, AND ANDERSEN C
Page 774 and 775: PARTRIDGE, JACOBSEN, AND ANDERSEN c
Page 778 and 779: PARTRIDGE, JACOBSEN, AND ANDERSEN v
Page 780 and 781: LESLIE R. SCHOVER Sexual Healing in
Page 782 and 783: LESLIE R. SCHOVER tinuous ADT in pr
Page 784 and 785: LESLIE R. SCHOVER 12. Potosky AL, H
Page 786 and 787: CATHERINE H. VAN POZNAK TABLE 1. Wo
Page 788 and 789: CATHERINE H. VAN POZNAK (tamoxifen,
Page 790 and 791: CATHERINE H. VAN POZNAK TABLE 3. FD
Page 792 and 793: CATHERINE H. VAN POZNAK premenopaus
Page 794 and 795: SHARI GOLDFARB KEY POINTS Brea
Page 796 and 797: SHARI GOLDFARB and friction with va
Page 798 and 799: SHARI GOLDFARB importance both duri
Page 800 and 801: PATIENT AND SURVIVOR CARE Moving Su
Page 802 and 803: MAYER ET AL TABLE 1. Quality Metric
Page 804 and 805: MAYER ET AL to enhance the quality
Page 806 and 807: MAYER ET AL FIGURE 2. (A) Infertili
Page 808 and 809: MAYER ET AL efıcial suggests that
Page 810 and 811: PATIENT AND SURVIVOR CARE The Chall
Page 812 and 813: BRUERA AND PAICE Choice of Opioid a
Page 814 and 815: BRUERA AND PAICE toxicity and proce
Page 816 and 817: BRUERA AND PAICE effective. Basic s
Page 818 and 819: PEDIATRIC ONCOLOGY Real-Time Molecu
Page 820 and 821: CARROLL, RAETZ, AND MEYER KEY POINT
Page 822 and 823: CARROLL, RAETZ, AND MEYER most are
Page 824 and 825: CARROLL, RAETZ, AND MEYER markers a
Page 826 and 827:
PEDIATRIC ONCOLOGY Translating Surv
Page 828 and 829:
REDUCING THE BURDEN OF LATE EFFECTS
Page 830 and 831:
Page 832 and 833:
Page 834 and 835:
Page 836 and 837:
PROFESSIONAL DEVELOPMENT The Challe
Page 838 and 839:
ADVANCES IN WEBSITE INFORMATION RES
Page 840 and 841:
Page 842 and 843:
Page 844 and 845:
Page 846 and 847:
COMMUNICATION AND TECHNOLOGY: IT’
Page 848 and 849:
Page 850 and 851:
Page 852 and 853:
PATIENT-REPORTED OUTCOMES IN ONCOLO
Page 854 and 855:
PATIENT-REPORTED OUTCOMES IN ONCOLO
Page 856 and 857:
PROFESSIONAL DEVELOPMENT Trends, An
Page 858 and 859:
CLINICAL ONCOLOGY PRACTICE 2015 FIG
Page 860 and 861:
CLINICAL ONCOLOGY PRACTICE 2015 (6.
Page 862 and 863:
CLINICAL ONCOLOGY PRACTICE 2015 Pro
Page 864 and 865:
ADJUVANT/NEOADJUVANT MEDICAL THERAP
Page 866 and 867:
Page 868 and 869:
Page 870 and 871:
INDICATIONS FOR ADJUVANT RADIATION
Page 872 and 873:
Page 874 and 875:
Page 876 and 877:
Page 878 and 879:
SARCOMA Latest Advances in Systemic
Page 880 and 881:
SYSTEMIC THERAPY FOR OSTEOSARCOMA A
Page 882 and 883:
SYSTEMIC THERAPY FOR OSTEOSARCOMA A
Page 884 and 885:
RETHINKING TREATMENT FOR CHONDROSAR
Page 886 and 887:
Page 888 and 889:
Page 890 and 891:
Page 892 and 893:
BONE SARCOMAS IN ADULTS local disea
Page 894 and 895:
BONE SARCOMAS IN ADULTS structure a
Page 896 and 897:
SARCOMA Well-Differentiated and Ded
Page 898 and 899:
ABBAS MANJI ET AL ticular region. 7
Page 900 and 901:
ABBAS MANJI ET AL MYXOID (ROUND CEL
Page 902 and 903:
ABBAS MANJI ET AL versus doxorubici
Page 904 and 905:
SHLUSH AND HERSHKOVITZ Clonal Evolu
Page 906 and 907:
SHLUSH AND HERSHKOVITZ FIGURE 1. Ti
Page 908 and 909:
TUMOR BIOLOGY New Strategies to Und
Page 910 and 911:
KNAPP, DHAWAN, AND OSTRANDER in dog
Page 912 and 913:
KNAPP, DHAWAN, AND OSTRANDER TABLE
Page 914 and 915:
KNAPP, DHAWAN, AND OSTRANDER 14. Fe
Page 916 and 917:
SOURBIER, SRINIVASAN, AND LINEHAN M
Page 918 and 919:
SOURBIER, SRINIVASAN, AND LINEHAN F
Page 920 and 921:
SOURBIER, SRINIVASAN, AND LINEHAN T
Page 922:
Author Index Abbas Manji, Gulam ...
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