31.05.2015 Views

NcXHF

NcXHF

NcXHF

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

ODENIKE, ONIDA, AND PADRON<br />

mendations from the European LeukemiaNet. Blood. 2013;122:2943-<br />

2964.<br />

9. Vaughn JE, Scott BL, Deeg HJ. Transplantation for myelodysplastic<br />

syndromes 2013. Curr Opin Hematol. 2013;20:494-500.<br />

10. Greenberg PL, Attar E, Bennett JM, et al. Myelodysplastic syndromes:<br />

clinical practice guidelines in oncology. J Natl Compr Cancer Netw.<br />

2013;11:838-874.<br />

11. Ofran Y, Lazarus HM, Rapoport AP, et al. Interpreting outcome data<br />

in hematopoietic cell transplantation for leukemia: tackling common<br />

biases. Bone Marrow Transpl. Epub 2015 Jan 12.<br />

12. Rollison DE, Howlader N, Smith MT, et al. Epidemiology of myelodysplastic<br />

syndromes and chronic myeloproliferative disorders in the<br />

United States, 2001-2004, using data from the NAACCR and SEER<br />

programs. Blood. 2008;112:45-52.<br />

13. Bennett JM, Catovsky D, Daniel MT, et al. Proposals for the classifıcation of<br />

the myelodysplastic syndromes. Br J Haematol. 1982;51:189-199.<br />

14. Vardiman JW, Thiele J, Arber DA, et al. The 2008 revision of the World<br />

Health Organization (WHO) classifıcation of myeloid neoplasms and<br />

acute leukemia: rationale and important changes. Blood. 2009;114:<br />

937-951.<br />

15. Greenberg P, Cox C, LeBeau MM, et al. International scoring system<br />

for evaluating prognosis in myelodysplastic syndromes. Blood. 1997;<br />

89:2079-2088.<br />

16. Malcovati L, Germing U, Kuendgen A, et al. Time-dependent prognostic<br />

scoring system for predicting survival and leukemic evolution in<br />

myelodysplastic syndromes. J Clin Oncol. 2007;25:3503-3510.<br />

17. Kantarjian H, O’Brien S, Ravandi F, et al. Proposal for a new risk model<br />

in myelodysplastic syndrome that accounts for events not considered<br />

in the original International Prognostic Scoring System. Cancer. 2008;<br />

113:1351-1361.<br />

18. Garcia-Manero G, Shan J, Faderl S, et al. A prognostic score for patients<br />

with lower risk myelodysplastic syndrome. Leukemia. 2008;22:<br />

538-543.<br />

19. Greenberg PL, Tuechler H, Schanz J, et al. Revised international prognostic<br />

scoring system for myelodysplastic syndromes. Blood. 2012;120:<br />

2454-2465.<br />

20. Schanz J, Tüchler H, Solé F, et al. New comprehensive cytogenetic<br />

scoring system for primary myelodysplastic syndromes (MDS) and<br />

oligoblastic acute myeloid leukemia after MDS derived from an international<br />

database merge. J Clin Oncol. 2012;30:820-829.<br />

21. Voso MT, Fenu S, Latagliata R, et al. Revised International Prognostic<br />

Scoring System (IPSS) predicts survival and leukemic evolution of myelodysplastic<br />

syndromes signifıcantly better than IPSS and WHO<br />

Prognostic Scoring System: validation by the Gruppo Romano Mielodisplasie<br />

Italian Regional Database. J Clin Oncol. 2013;31:2671-2677.<br />

22. Mishra A, Corrales-Yepez M, Ali NA, et al. Validation of the revised<br />

International Prognostic Scoring System in treated patients with myelodysplastic<br />

syndromes. Am J Hematol. 2013;88:566-570.<br />

23. Breccia M, Salaroli A, Loglisci G, et al. Revised IPSS (IPSS-R) stratifıcation<br />

and outcome of MDS patients treated with azacitidine. Ann Hematol.<br />

2013;92:411-412.<br />

24. Bejar R, Stevenson K, Abdel-Wahab O, et al. Clinical effect of point<br />

mutations in myelodysplastic syndromes. N Engl J Med. 2011;364:<br />

2496-2506.<br />

25. Bejar R, Stevenson KE, Caughey BA, et al. Validation of a prognostic<br />

model and the impact of mutations in patients with lower-risk myelodysplastic<br />

syndromes. J Clin Oncol. 2012;30:3376-3382.<br />

26. Odenike O, Le Beau MM. The dawn of the molecular era of the myelodysplastic<br />

syndromes. N Engl J Med. 2011;364:2545-2546.<br />

27. Haferlach T, Nagata Y, Grossmann V, et al. Landscape of genetic lesions<br />

in 944 patients with myelodysplastic syndromes. Leukemia.<br />

2014;28:241-247.<br />

28. Papaemmanuil E, Cazzola M, Boultwood J, et al. Somatic SF3B1 mutation<br />

in myelodysplasia with ring sideroblasts. N Engl J Med. 2011;<br />

365:1384-1395.<br />

29. Yoshida K, Sanada M, Shiraishi Y, et al. Frequent pathway mutations<br />

of splicing machinery in myelodysplasia. Nature. 2011;478:64-69.<br />

30. Walter MJ, Shen D, Ding L, et al. Clonal architecture of secondary<br />

acute myeloid leukemia. N Engl J Med. 2012;366:1090-1098.<br />

31. Malcovati L, Papaemmanuil E, Ambaglio I, et al. Driver somatic mutations<br />

identify distinct disease entities within myeloid neoplasms with<br />

myelodysplasia. Blood. 2014;124:1513-1521.<br />

32. Hellström-Lindberg E, Gulbrandsen N, Lindberg G, et al. A validated<br />

decision model for treating the anaemia of myelodysplastic syndromes<br />

with erythropoietin granulocyte colony-stimulating factor: signifıcant<br />

effects on quality of life. Br J Haematol. 2003;120:1037-1046.<br />

33. Olnes MJ, Sloand EM. Targeting immune dysregulation in myelodysplastic<br />

syndromes. JAMA. 2011;305:814-819.<br />

34. Saunthararajah Y, Nakamura R, Wesley R, et al. A simple method to<br />

predict response to immunosuppressive therapy in patients with myelodysplastic<br />

syndrome. Blood. 2003;102:3025-3027.<br />

35. Lim ZY, Killick S, Germing U, et al. Low IPSS score and bone marrow<br />

hypocellularity in MDS patients predict hematological responses to<br />

antithymocyte globulin. Leukemia. 2007;21:1436-1441.<br />

36. Kadia TM, Borthakur G, Garcia-Manero G, et al. Final results of the<br />

phase II study of rabbit anti-thymocyte globulin, ciclosporin, methylprednisone,<br />

and granulocyte colony-stimulating factor in patients<br />

with aplastic anaemia and myelodysplastic syndrome. Br J Haematol.<br />

2012;157:312-320.<br />

37. Komrokji RS, Mailloux AW, Chen DT, et al. A phase II multicenter<br />

rabbit anti-thymocyte globulin trial in patients with myelodysplastic<br />

syndromes identifying a novel model for response prediction. Haematologica.<br />

2014;99:1176-1183.<br />

38. List A, Dewald G, Bennett J, et al. Lenalidomide in the myelodysplastic<br />

syndrome with chromosome 5q deletion. N Engl J Med. 2006;355:<br />

1456-1465.<br />

39. Raza A, Reeves JA, Feldman EJ, et al. Phase 2 study of lenalidomide in<br />

transfusion-dependent, low-risk, and intermediate-1 risk myelodysplastic<br />

syndromes with karyotypes other than deletion 5q. Blood. 2008;<br />

111:86-93.<br />

40. Mallo M, Del Rey M, Ibáňez M, et al. Response to lenalidomide in myelodysplastic<br />

syndromes with del(5q): influence of cytogenetics and<br />

mutations. Br J Haematol. 2013;162:74-86.<br />

41. Komrokji RS, Lancet JE, Swern AS, et al. Combined treatment with<br />

lenalidomide and epoetin alfa in lower-risk patients with myelodysplastic<br />

syndrome. Blood. 2012;120:3419-3424.<br />

42. Fink EC, Krönke J, Hurst S, et al. Lenalidomide induces ubiquitination<br />

and degradation of CSNK1A1 in MDS with Del(5q). Paper presented<br />

at: 56th Annual Meeting of the American Society of Hematology; December<br />

2014; San Francisco, CA.<br />

43. Chen J, Odenike O, Rowley JD. Leukaemogenesis: more than mutant<br />

genes. Nat Rev Cancer. 2010;10:23-36.<br />

44. Fenaux P, Mufti GJ, Hellström-Lindberg E, et al. Azacitidine prolongs<br />

overall survival compared with conventional care regimens in elderly<br />

patients with low bone marrow blast count acute myeloid leukemia.<br />

J Clin Oncol. 2010;28:562-569.<br />

45. Kantarjian H, Issa JP, Rosenfeld CS, et al. Decitabine improves patient<br />

outcomes in myelodysplastic syndromes: results of a phase III randomized<br />

study. Cancer. 2006;106:1794-1803.<br />

46. Silverman LR, Demakos EP, Peterson BL, et al. Randomized controlled<br />

trial of azacitidine in patients with the myelodysplastic syndrome: a<br />

study of the cancer and leukemia group B. J Clin Oncol. 2002;20:2429-<br />

2440.<br />

47. Wang R, Gross CP, Frick K, et al. The impact of hypomethylating<br />

e408<br />

2015 ASCO EDUCATIONAL BOOK | asco.org/edbook

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!