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RADIUM 223 AND METASTATIC CASTRATION-RESISTANT PROSTATE CANCER References 1. Sartor O, Reid RH, Hoskin PJ, et al. Samarium-153-Lexidronam complex for treatment of painful bone metastases in hormone-refractory prostate cancer. Urology. 2004;63:940-945. 2. Lewington VJ, McEwanAJ, Ackery DM, et al. A prospective, randomised double-blind crossover study to examine the effıcacy of strontium-89 in pain palliation in patients with advanced prostate cancer metastatic to bone. Eur J Cancer. 1991;27:954-958. 3. Parker C, Nilsson S, Heinrich D, et al. Alpha emitter radium-223 and survival in metastatic prostate cancer. N Engl J Med. 2013;369:213- 223. 4. Hoskin P, Sartor O, O’Sullivan JM, et al. Effıcacy and safety of radium 223 in patients with castration-resistant prostate cancer and symptomatic bone metastases, with or without previous docetaxel use: a prespecifıed subgroup analysis from the randomised, double-blind, phase 3 ALSYMPCA trial. Lancet Oncol. 2014;15:1397-1406. 5. Sartor O, Coleman R, Nilsson S, et al. Effect of radium 223 on symptomatic skeletal events in patients with castration-resistant prostate cancer and bone metastases: results from a phase 3, double-blind, randomised trial. Lancet Oncol. 2014;15:738-746. 6. Morris MJ, Hammers HJ, Sweeney CJ, et al. Safety of radium 223 (Ra- 223) with docetaxel (D) in patients with bone metastases from castration-resistant prostate cancer (CRPC): A phase I Prostate Cancer Clinical Trials Consortium Study. J Clin Oncol. 2013;31 (suppl; abstr 5021). 7. Nilsson S, Vogelzang NJ, Sartor AO, et al. 1.5 year post-treatment follow-up of radium-223 (Ra-223) dichloride in patients with castration-resistant prostate cancer (CRPC) and bone metastases from the phase 3 ALSYMPCA study. J Clin Oncol. 2014; 32 (suppl 4; abstr 9). 8. Logothetis CJ, Basch E, Molina A, et al. Effect of abiraterone acetate and prednisone compared with placebo and prednisone on pain control and skeletal-related events in patients with metastatic castration-resistant prostate cancer: exploratory analysis of data from the COU-AA-301 randomised trial. Lancet Oncol. 2012;13:1210-1217. 9. Fizazi K, Scher HI, Miller K, et al. Effect of enzalutamide on time to fırst skeletal-related event, pain, and quality of life in men with castrationresistant prostate cancer: results from the randomised, phase 3 AFFIRM trial. Lancet Oncol. 2014;15:1147-1156. 10. Nilsson S, Larsen RH, Fosså SD, et al. First clinical experience with alpha-emitting radium-223 in the treatment of skeletal metastases. Clin Cancer Res. 2005;11:4451-5559. 11. Nilsson S, Franzén L, Parker C, et al. Bone-targeted radium-223 in symptomatic, hormone-refractory prostate cancer: a randomised, multicentre, placebo-controlled phase II study. Lancet Oncol. 2007;8:587- 594. asco.org/edbook | 2015 ASCO EDUCATIONAL BOOK e273
GENITOURINARY CANCER Immunotherapy for Genitourinary Tumors: Are We Ready for Prime Time? CHAIR Susan F. Slovin, MD, PhD Memorial Sloan Kettering Cancer Center New York, NY SPEAKERS Piyush K. Agarwal, MD National Cancer Institute at the National Institutes of Health Bethesda, MD David F. McDermott, MD Beth Israel Deaconess Medical Center Boston, MA
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AMERICAN SOCIETY OF CLINICAL ONCOLO
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American Society of Clinical Oncolo
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Controversies in Neoadjuvant Therap
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Clinical Trials of Precision Medici
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Managing Ovarian Cancer in the Olde
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Updates in the Multimodality Manage
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PEDIATRIC ONCOLOGY Real-Time Molecu
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2015 ASCO Annual Meeting Disclosure
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2015 Educational Book Expert Panel
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James Marshall, PhD Roswell Park Ca
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2015 Annual Meeting Supporters* MIS
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David Yurman Corporate Allies Conqu
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INVITED ARTICLES This year’s invi
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WONG, CAPASSO, AND ECKHARDT 3 3 sc
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WONG, CAPASSO, AND ECKHARDT terize
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WONG, CAPASSO, AND ECKHARDT for mul
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STEPHEN T. SONIS portantly, patient
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STEPHEN T. SONIS elements of a clus
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STEPHEN T. SONIS Defıning the clin
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STEPHEN T. SONIS predict oral mucos
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HUSSAIN AND DIPAOLA TABLE 1. U.S. F
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HUSSAIN AND DIPAOLA mizing use of p
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INVITED ARTICLES DIAGNOSTICS The Fu
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EDWARD S. KIM TABLE 1. Selected Umb
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EDWARD S. KIM platform that plans t
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INVITED ARTICLES HEAD AND NECK CANC
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GROSS AND COHEN treatments are poor
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GROSS AND COHEN 22. Ratner M. Pharm
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GILBERT ET AL tional scholars, lead
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GILBERT ET AL ment of physician com
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GILBERT ET AL greater understanding
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INVITED ARTICLES GASTROINTESTINAL C
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ENG ET AL colorectal cancer. Indeed
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INVITED ARTICLES BREAST CANCER I Wi
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WILLIAM M. SIKOV gational treatment
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DELUCHE, ONESTI, AND ANDRE Precisio
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DELUCHE, ONESTI, AND ANDRE the path
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DELUCHE, ONESTI, AND ANDRE combine
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SALAMA AND CHMURA Surgery or Ablati
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SALAMA AND CHMURA TABLE 1. Frequenc
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SALAMA AND CHMURA per patient was 8
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SALAMA AND CHMURA 4. Fisher B. Labo
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BREAST CANCER Controversies in Neoa
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WHITE AND DEMICHELE KEY POINTS
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WHITE AND DEMICHELE growing body of
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WHITE AND DEMICHELE signed with app
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BREAST CANCER Individualizing the A
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OLDER WOMEN WITH EARLY-STAGE BREAST
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IMMUNITY IN TRIPLE-NEGATIVE BREAST
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MOLECULAR SUBTYPES AND NEW TARGETS
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ADJUVANT AND NEOADJUVANT THERAPY FO
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CANCER PREVENTION, GENETICS, AND EP
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ADDRESSING BARRIERS TO BREAST CANCE
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DECISION MAKING IN THE CONTEXT OF B
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SCHIFFMAN, FISHER, AND GIBBS econom
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SCHIFFMAN, FISHER, AND GIBBS High-r
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SCHIFFMAN, FISHER, AND GIBBS could
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SCHIFFMAN, FISHER, AND GIBBS due to
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CAN DIET AND LIFESTYLE PREVENT BREA
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REFORMING THE BUY-AND-BILL CHEMOTHE
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CARE DELIVERY AND PRACTICE MANAGEME
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THE PATIENT-CENTERED MEDICAL HOME c
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THE PATIENT-CENTERED MEDICAL HOME F
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THE PATIENT-CENTERED MEDICAL HOME F
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THE PATIENT-CENTERED MEDICAL HOME c
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INTEGRATING ICD-10 IN YOUR PRACTICE
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CENTRAL NERVOUS SYSTEM TUMORS Brain
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AHLUWALIA AND WINKLER TARGETING ANG
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AHLUWALIA AND WINKLER cancer brain
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AHLUWALIA AND WINKLER However, the
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AHLUWALIA AND WINKLER in patients w
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MEHTA AND AHLUWALIA of SRS for brai
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MEHTA AND AHLUWALIA for patients ol
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MEHTA AND AHLUWALIA 14. Atalar B, M
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MAWRIN, CHUNG, AND PREUSSER Biology
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MAWRIN, CHUNG, AND PREUSSER Fibrobl
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MAWRIN, CHUNG, AND PREUSSER grade a
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MAWRIN, CHUNG, AND PREUSSER Disclos
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MAWRIN, CHUNG, AND PREUSSER 72. Sur
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DEVELOPMENTAL THERAPEUTICS AND TRAN
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ESTEVA, MILLER, AND TEICHER TARGETS
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ESTEVA, MILLER, AND TEICHER gle che
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ESTEVA, MILLER, AND TEICHER TABLE 2
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ESTEVA, MILLER, AND TEICHER 21. Ans
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STUART M. LICHTMAN include a Geriat
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STUART M. LICHTMAN an outcome of ca
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BARRIOS, WERUTSKY, AND MARTINEZ-MES
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MANDREKAR, DAHLBERG, AND SIMON FIGU
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MANDREKAR, DAHLBERG, AND SIMON FIGU
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MANDREKAR, DAHLBERG, AND SIMON know
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DIENSTMANN, SALAZAR, AND TABERNERO
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RIMAWI, DE ANGELIS, AND SCHIFF FIGU
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RIMAWI, DE ANGELIS, AND SCHIFF TABL
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RIMAWI, DE ANGELIS, AND SCHIFF tent
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RIMAWI, DE ANGELIS, AND SCHIFF phas
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CHRISTINE M. LOVLY TKIs have been t
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CHRISTINE M. LOVLY EGFR TKIs appear
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CHRISTINE M. LOVLY MAP2K1, which en
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CHRISTINE M. LOVLY patients with ad
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DAMODARAN, BERGER, AND ROYCHOWDHURY
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ZARDAVAS AND PICCART-GEBHART TABLE
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ZARDAVAS AND PICCART-GEBHART TABLE
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ZARDAVAS AND PICCART-GEBHART triple
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ZARDAVAS AND PICCART-GEBHART mutati
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MICHAEL A. POSTOW Managing Immune C
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MICHAEL A. POSTOW diarrhea symptoms
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MICHAEL A. POSTOW tion. One of thes
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MICHAEL A. POSTOW nitis during ipil
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GASTROINTESTINAL (COLORECTAL) CANCE
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PRECISION THERAPY FOR RECTAL CANCER
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PRECISION THERAPY FOR RECTAL CANCER
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GASTROINTESTINAL (COLORECTAL) CANCE
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MARWAN FAKIH was offset by a detrim
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MARWAN FAKIH TABLE 1. Biologicals i
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MARWAN FAKIH TABLE 3. EGFR Targetin
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MARWAN FAKIH TABLE 6. EGFR Targetin
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MARWAN FAKIH 5-fluorouracil (FOLFIR
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PUNT, SIMKENS, AND KOOPMAN 5-FU/LV
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PUNT, SIMKENS, AND KOOPMAN TABLE 1.
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PUNT, SIMKENS, AND KOOPMAN 35. Veno
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CERCEK, CUSACK, AND RYAN Treatment
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CERCEK, CUSACK, AND RYAN leagues pe
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GASTROINTESTINAL (NONCOLORECTAL) CA
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ABOU-ALFA ET AL sess liver function
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ABOU-ALFA ET AL tinuing liver injur
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ABOU-ALFA ET AL mors including HCC,
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ABOU-ALFA ET AL HCC (Anti-Programme
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AHN ET AL Making Sense of Current a
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AHN ET AL Pancreatic cancer has bee
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AHN ET AL Disclosures of Potential
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GASTROINTESTINAL (NONCOLORECTAL) CA
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EGIDIO DEL FABBRO tion of precachex
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EGIDIO DEL FABBRO FIGURE 3. Mechani
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EGIDIO DEL FABBRO II RCT of ghrelin
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Page 388 and 389: SALVAGE CHEMOTHERAPY References 1.
Page 390 and 391: EARLY CHEMOTHERAPY IN MEN WITH META
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Page 446 and 447: GYNECOLOGIC CANCER Managing Ovarian
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DUSKA, TEW, AND MOORE FIGURE 2. Sur
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DUSKA, TEW, AND MOORE FIGURE 3. Che
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DUSKA, TEW, AND MOORE FIGURE 4. Ger
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DUSKA, TEW, AND MOORE 10. Griffıth
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GYNECOLOGIC CANCER Treatment of the
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CHEMOTHERAPY FOR PATIENTS WITH BMOC
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PROGRESS IN HEAD AND NECK SQUAMOUS
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HEAD AND NECK CANCER PI3-Kinase: Ge
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ISAACSSON VELHO, CASTRO JR, AND CHU
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SHARON H. GIORDANO Comparative Effe
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SHARON H. GIORDANO measured confoun
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SHARON H. GIORDANO These databases
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HEALTH SERVICES RESEARCH AND QUALIT
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INDUSTRY AND ONCOLOGY KEY POINTS F
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INDUSTRY AND ONCOLOGY has been “l
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INDUSTRY AND ONCOLOGY by (covered)
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INDUSTRY AND ONCOLOGY 42. World Hea
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CANCER CARE QUALITY: CURRENT STATE
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MANAGING OLDER PATIENTS WITH ALL Th
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MANAGING OLDER PATIENTS WITH ALL TA
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MANAGING OLDER PATIENTS WITH ALL FI
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MANAGING OLDER PATIENTS WITH ALL FI
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MANAGING OLDER PATIENTS WITH ALL ra
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TREATMENT OF PHILADELPHIA CHROMOSOM
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CD19 CAR THERAPY FOR ALL FIGURE 1.
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CD19 CAR THERAPY FOR ALL 5. Zhou G,
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NEW TARGETED THERAPIES FOR iNHL New
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NEW TARGETED THERAPIES FOR iNHL TAB
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NEW TARGETED THERAPIES FOR iNHL a P
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HEMATOPOIETIC CELL TRANSPLANTATION
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LEUKEMIA, MYELODYSPLASIA, AND TRANS
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MICHAEL W. DEININGER TABLE 1. Defin
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MICHAEL W. DEININGER the ATP-bindin
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MICHAEL W. DEININGER broad range ef
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MICHAEL W. DEININGER 30. Hughes T,
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PEMMARAJU AND MOLITERNO TABLE 1. Ac
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PEMMARAJU AND MOLITERNO drome (BCS)
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PEMMARAJU AND MOLITERNO 13. Xing S,
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THERAPIES AND INDICATIONS FOR PH-NE
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LEUKEMIA, MYELODYSPLASIA, AND TRANS
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RECENT UPDATES IN MDS AND MDS/MPNS
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LUNG CANCER Beyond Second-Line Trea
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BEYOND SECOND-LINE TREATMENT FOR LU
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BEYOND SECOND-LINE TREATMENT FOR LU
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LUNG CANCER New Therapies for Histo
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GERBER, PAIK, AND DOWLATI a tumor t
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GERBER, PAIK, AND DOWLATI squamous
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GERBER, PAIK, AND DOWLATI FIGURE 2.
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GERBER, PAIK, AND DOWLATI TABLE 1.
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GERBER, PAIK, AND DOWLATI gression
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GERBER, PAIK, AND DOWLATI Disclosur
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GERBER, PAIK, AND DOWLATI enzyme in
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GERBER, PAIK, AND DOWLATI receptor
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LILENBAUM, LEIGHL, AND NEUBAUER Exp
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LILENBAUM, LEIGHL, AND NEUBAUER tha
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LILENBAUM, LEIGHL, AND NEUBAUER Ref
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BERNARDO H.L. GOULART The Value of
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BERNARDO H.L. GOULART TABLE 1. Expe
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BERNARDO H.L. GOULART every 6 month
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BERNARDO H.L. GOULART lung-cancer/l
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LUNG CANCER Updates in the Multimod
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WOODARD AND JABLONS section, becaus
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WOODARD AND JABLONS mediastinum is
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WOODARD AND JABLONS FIGURE 1. Molec
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NASSER HANNA Current Standards and
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NASSER HANNA At the 2014 ASCO Annua
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NASSER HANNA culty of this task. Va
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LYMPHOMA AND PLASMA CELL DISORDERS
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NOWAKOWSKI AND CZUCZMAN sociated wi
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NOWAKOWSKI AND CZUCZMAN trial is in
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NOWAKOWSKI AND CZUCZMAN TABLE 2. DH
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NOWAKOWSKI AND CZUCZMAN 15. Aragon-
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DAVID W. SCOTT Cell-of-Origin in Di
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DAVID W. SCOTT FIGURE 1. The Origin
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DAVID W. SCOTT FIGURE 2. Immunohist
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DAVID W. SCOTT FIGURE 3. The Lymph2
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DAVID W. SCOTT 10. Shaffer AL 3rd,
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CHEAH, OKI, AND FANALE Novel Treatm
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CHEAH, OKI, AND FANALE an ongoing G
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CHEAH, OKI, AND FANALE a similar me
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CHEAH, OKI, AND FANALE TABLE 3. Sel
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CHEAH, OKI, AND FANALE eral T cell
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CHEAH, OKI, AND FANALE 77. Cairns R
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STEPHEN ANSELL associated with pati
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STEPHEN ANSELL Disclosures of Poten
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MATEOS AND SAN MIGUEL Smoldering Mu
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MATEOS AND SAN MIGUEL years. This f
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MATEOS AND SAN MIGUEL previously me
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MATEOS AND SAN MIGUEL TABLE 2. Risk
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MATEOS AND SAN MIGUEL 30. Rajkumar
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BHUTANI, LANDGREN, AND USMANI of th
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BHUTANI, LANDGREN, AND USMANI bette
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BHUTANI, LANDGREN, AND USMANI fıne
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BHUTANI, LANDGREN, AND USMANI FIGUR
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BHUTANI, LANDGREN, AND USMANI 15. K
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MOREAU AND TOUZEAU Multiple Myeloma
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MOREAU AND TOUZEAU other effıcacy
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MOREAU AND TOUZEAU was able to indu
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MOREAU AND TOUZEAU Group consensus
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LYMPHOMA AND PLASMA CELL DISORDERS
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MANAGEMENT OF CLL Up-Front Manageme
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MANAGEMENT OF CLL than 17p-/TP53mut
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MANAGEMENT OF CLL could be associat
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MANAGEMENT OF CLL tion by nonmalign
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MANAGEMENT OF CLL fludarabine and c
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MANAGEMENT OF CLL lymphocytic leuke
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PROGNOSTIC FACTORS AND ADJUVANT RAD
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MERKEL CELL CARCINOMA Merkel Cell C
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MERKEL CELL CARCINOMA tions in PIK3
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MERKEL CELL CARCINOMA treating MCC
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MERKEL CELL CARCINOMA 32. Leonard J
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MELANOMA/SKIN CANCERS Locoregional
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PERFUSION AND INFUSION IN THE ERA O
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NEOADJUVANT THERAPY OF MELANOMA Neo
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NEOADJUVANT THERAPY OF MELANOMA TAB
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NEOADJUVANT THERAPY OF MELANOMA ity
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NEOADJUVANT THERAPY OF MELANOMA 4.
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MELANOMA/SKIN CANCERS Targeted Mole
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SULLIVAN ET AL FIGURE 1. Relevant S
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SULLIVAN ET AL Resistance to BRAF i
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SULLIVAN ET AL TABLE 1. Clinical Tr
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SULLIVAN ET AL 17. Halait H, Demart
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SULLIVAN ET AL NRAS-mutant melanoma
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KLEPIN, RODIN, AND HURRIA Treating
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KLEPIN, RODIN, AND HURRIA plication
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KLEPIN, RODIN, AND HURRIA plan was
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KLEPIN, RODIN, AND HURRIA patient-s
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KLEPIN, RODIN, AND HURRIA 62. Blanc
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PERIPHERAL NEUROTOXICITY IN CANCER
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PARTRIDGE, JACOBSEN, AND ANDERSEN C
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PARTRIDGE, JACOBSEN, AND ANDERSEN c
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PARTRIDGE, JACOBSEN, AND ANDERSEN w
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PARTRIDGE, JACOBSEN, AND ANDERSEN v
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LESLIE R. SCHOVER Sexual Healing in
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LESLIE R. SCHOVER tinuous ADT in pr
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LESLIE R. SCHOVER 12. Potosky AL, H
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CATHERINE H. VAN POZNAK TABLE 1. Wo
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CATHERINE H. VAN POZNAK (tamoxifen,
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CATHERINE H. VAN POZNAK TABLE 3. FD
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CATHERINE H. VAN POZNAK premenopaus
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SHARI GOLDFARB KEY POINTS Brea
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SHARI GOLDFARB and friction with va
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SHARI GOLDFARB importance both duri
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PATIENT AND SURVIVOR CARE Moving Su
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MAYER ET AL TABLE 1. Quality Metric
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MAYER ET AL to enhance the quality
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MAYER ET AL FIGURE 2. (A) Infertili
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MAYER ET AL efıcial suggests that
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PATIENT AND SURVIVOR CARE The Chall
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BRUERA AND PAICE Choice of Opioid a
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BRUERA AND PAICE toxicity and proce
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BRUERA AND PAICE effective. Basic s
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PEDIATRIC ONCOLOGY Real-Time Molecu
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CARROLL, RAETZ, AND MEYER KEY POINT
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CARROLL, RAETZ, AND MEYER most are
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CARROLL, RAETZ, AND MEYER markers a
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PEDIATRIC ONCOLOGY Translating Surv
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REDUCING THE BURDEN OF LATE EFFECTS
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Page 832 and 833:
Page 834 and 835:
Page 836 and 837:
PROFESSIONAL DEVELOPMENT The Challe
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ADVANCES IN WEBSITE INFORMATION RES
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COMMUNICATION AND TECHNOLOGY: IT’
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Page 850 and 851:
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PATIENT-REPORTED OUTCOMES IN ONCOLO
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PATIENT-REPORTED OUTCOMES IN ONCOLO
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PROFESSIONAL DEVELOPMENT Trends, An
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CLINICAL ONCOLOGY PRACTICE 2015 FIG
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CLINICAL ONCOLOGY PRACTICE 2015 (6.
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CLINICAL ONCOLOGY PRACTICE 2015 Pro
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ADJUVANT/NEOADJUVANT MEDICAL THERAP
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Page 868 and 869:
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INDICATIONS FOR ADJUVANT RADIATION
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Page 874 and 875:
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SARCOMA Latest Advances in Systemic
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SYSTEMIC THERAPY FOR OSTEOSARCOMA A
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SYSTEMIC THERAPY FOR OSTEOSARCOMA A
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RETHINKING TREATMENT FOR CHONDROSAR
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Page 888 and 889:
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BONE SARCOMAS IN ADULTS local disea
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BONE SARCOMAS IN ADULTS structure a
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SARCOMA Well-Differentiated and Ded
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ABBAS MANJI ET AL ticular region. 7
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ABBAS MANJI ET AL MYXOID (ROUND CEL
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ABBAS MANJI ET AL versus doxorubici
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SHLUSH AND HERSHKOVITZ Clonal Evolu
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SHLUSH AND HERSHKOVITZ FIGURE 1. Ti
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TUMOR BIOLOGY New Strategies to Und
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KNAPP, DHAWAN, AND OSTRANDER in dog
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KNAPP, DHAWAN, AND OSTRANDER TABLE
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KNAPP, DHAWAN, AND OSTRANDER 14. Fe
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SOURBIER, SRINIVASAN, AND LINEHAN M
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SOURBIER, SRINIVASAN, AND LINEHAN F
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SOURBIER, SRINIVASAN, AND LINEHAN T
Page 922:
Author Index Abbas Manji, Gulam ...
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