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Scientific Concept of the National Cohort (status ... - Nationale Kohorte

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Diet *<br />

Modules<br />

Simplified 24-h diet recalls (web-based; also available<br />

as paper version) (1x in study center, 3x at home)<br />

Short food list (web-based; also available as paper<br />

version)<br />

Exact 24-h recalls by telephone (EPIC-SOFT, 3x)<br />

(level 2 only)<br />

Environmental factors<br />

Job and home address (for linkage with geocoded<br />

environmental data),<br />

Medical radiation exposure<br />

Occupational questions *<br />

[Work-related stress; listed under “psychosocial<br />

factors”]<br />

Screening questions for specific conditions, e.g. shift<br />

work<br />

Health care utilization and compliance<br />

Health insurance (type, insurance member’s number)<br />

Social security number<br />

Health care utilization: general practitioner visits, which<br />

<strong>of</strong> 16 medical subspecialties (Fachärzte) visited how<br />

<strong>of</strong>ten during past 3 months, ambulatory and inpatient<br />

treatment past 12 months<br />

75<br />

Interview<br />

X<br />

A.3 Study design<br />

Assessment Instruments<br />

Touch<br />

Screen<br />

X<br />

SAQ<br />

(paper)<br />

X<br />

X X<br />

Adherence to medication (Morisky Score) X<br />

O<strong>the</strong>r modules for specific subgroups<br />

Questions only for cancer survivors: various modules X<br />

*Fur<strong>the</strong>r details will be clarified in feasibility studies (see Sect. A.3.3.11)<br />

Neurologic and psychiatric factors<br />

X<br />

Webbased<br />

The lifetime prevalence <strong>of</strong> psychiatric disorders such as major depression, anxiety disorders,<br />

or addiction is over 45% and rising 472 . The disorders usually start early in life, i.e.,<br />

in adolescence or early adulthood, and very <strong>of</strong>ten are chronically progressive and recurrent.<br />

The individual and economic burdens caused by psychiatric disorders are very high:<br />

four psychiatric diseases are found among <strong>the</strong> 10 leading causes <strong>of</strong> disability worldwide,<br />

major depression being <strong>the</strong> number one for burden <strong>of</strong> disease in high- and middle-income<br />

countries even before CVD55. About 10–15% <strong>of</strong> patients commit suicide during <strong>the</strong> course<br />

<strong>of</strong> <strong>the</strong>se diseases, and even without clinically relevant symptoms mental disorders may<br />

enhance overall mortality 473 . Psychiatric disorders show a high rate <strong>of</strong> comorbidity with somatic<br />

diseases.<br />

The proposed instruments include scales for assessing depressive symptoms, anxiety, personality,<br />

and chronic stress.<br />

X<br />

X<br />

A.3

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