Scientific Concept of the National Cohort (status ... - Nationale Kohorte

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A.3 A.3 Study design Table 3.2: Description of the source population (at the administrative level of city or county), by study center Unemployment rate $ Population movement over the past 10 years Population density § Subjects with age 70 and above § Subjects below age 20 § Non- German citizens § * Females § * Study center, community Source population § * (%) (total inhabitants per km²) (% of total population) (% of total population) (%) (%) (N) (in % / year) Germany 54,799,164 49.7 10.1 19.0 14.1 229.6 +0.14 8.2 8.3 3.8 3.6 7.2 3.6 +0.55 +0.28 +0.46 +0.80 +0.51 1793.0 224.3 163.6 1656.6 131.3 14.5 12.6 11.8 13.9 11.9 17.9 21.9 22.2 16.2 21.6 19.4 7.7 6.5 13.0 4.8 50.1 50.0 49.7 50.6 49.5 177,851 157,544 84,228 93,400 121,688 Bavaria Augsburg city County of Augsburg County of Aichach-Friedberg Regensburg city County of Regensburg Baden-Wuerttemberg/Saarland 4.2 6.9 +0.19 +0.82 2147.8 1435.2 13.4 11.5 16.4 17.0 25.9 15.5 49.0 51.4 215,144 156,918 Mannheim city Freiburg city County of Emmendingen Saarbruecken city Saar-Palatinate county 58 3.9 +0.53 231.9 13.1 21.4 7.4 50.2 10.4 6.5 -0.04 -0.04 817 360 15.4 16.4 18.5 19.0 11.1 6.8 50.4 50.1 103,333 221,509 97,480 9.6 12.3 8.4 10.3 6.5 10.8 +0.37 -0.01 +0.10 +0.01 +0.16 +0.12 2689.7 2756.7 1843.4 2603.1 904.1 377.1 13.7 16.0 17.0 15.2 12.7 13.6 16.8 17.9 17.9 16.8 18.0 21.3 20.4 13.6 11.3 12.8 7.1 8.6 51.4 50.5 51.0 54.4 52.5 50.0 405,859 383,586 109,537 257,462 189,812 1,696,035 North Rhine-Westphalia Duesseldorf city Essen city Muelheim a. d. Ruhr city Bochum city Muenster city County of Muenster Saxony/Saxony-Anhalt 13.9 12.8 15.0 12.8 -1.07 -0.16 0.57 -0.14 1725.8 140.4 1732.1 361.5 15.3 14.9 15.2 15.7 15.0 15.0 14.4 15.5 4.0 1.6 7.3 1.5 50.8 48.7 49.5 48.9 162,339 141,078 363,208 186,837 14.1 +0.12 3860 18.8 (>65) 16.4 16.7 49.5 2,223,584 5.4 +0.16 265 16.6 16.9 2.3 48.7 679,417 Halle city Saalekreis Leipzig city County of Leipzig Berlin-Brandenburg Berlin city Adjacent suburban municipalities in Brandenburg
Unemployment rate $ Population movement over the past 10 years Population density § Subjects with age 70 and above § Subjects below age 20 § Non- German citizens § * Females § * Study center, community Source population § * (%) (total inhabitants per km²) (% of total population) (% of total population) (%) (%) (N) (in % / year) 8.6 11.1 10.7 5.6 +0.52 +0.34 -0.27 +0.59 2346.2 1683.0 1195.0 254.0 13.0 14.8 14.0 13.5 17.3 17.3 20.1 21.0 16.9 15.3 10.1 4.9 49.8 50.1 49.9 50.1 1,235,336 371,356 49,286 11,900 4.3 9.4 +0.54 +0.74 178.8 170.0 15.2 12.3 24.7 22.2 8.6 5.2 48.8 49.5 71,800 36,400 6.6 5.3 9.4 +0.38 +0.45 +0.74 93.1 158.4 127.0 11.2 12.3 12.3 26.1 22.2 22.2 5.7 5.2 5.2 48.4 49.1 49.5 17,100 10,750 10,260 Lower Saxony/Hamburg/Bremen Hamburg city Bremen city Delmenhorst city Lilienthal South-West Bremen: Northern county of Vechta Parts of county of Oldenburg (Municipalities Ganderkesse, Doetlingen, Wildeshausen) Northeast county of Cloppenburg Municipality Diepholz Municipality Hude Brunswick/Hanover: Brunswick city County of Peine Eastern region of Hanover 59 9.3 7.7 9.3 10.7 +0.24 +0.40 +0.23 +0.21 1,287 247.9 288.5 2543.4 14.7 14.2 14.3 13.7 16,8 21.3 18.5 16.8 11.2 7.0 11.7 16.4 48.8 49.6 50.4 50.5 168,813 86,985 182,700 358,804 10.9 6.1 +0.42 +0.20 2002.4 124.1 12.6 13.9 16.8 21.5 9.4 3.6 48.7 59.9 170,916 175,381 Hanover city Schleswig-Holstein Kiel city County of Rendsburg-Eckernfoerde Mecklenburg-Western Pomerania Neubrandenburg city County of Demmin County of Uecker-Randow County of Mecklenburg-Strelitz County of Mueritz A.3 Study design 15.1 18.3 17.2 15.1 12.7 -1.28 -1.22 -1.14 -0.79 -0.42 866.5 50.5 53.8 42.4 41.0 14.5 16.0 16.2 15.1 15.0 14.9 15.9 15.1 15.6 15.9 2.3 1.7 3.6 1.6 1.7 49.8 47.8 47.5 54.0 54.7 52,899 64,010 58,366 59,025 47,038 * figures are related to subjects in the age range of 20-69 years; (main data source: https://www.regionalstatistik.de/genesis/online/, status September 2010) §: data on dec 31 2008, $: data for the year 2009 A.3
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The National Cohort A prospective e
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Applicants Applicants Applicants Cl
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Applicants IV
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Executive Summary 2. The National C
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Executive Summary 3. Scientific aim
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Executive Summary essary to address
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Executive Summary 7. Examples for s
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Contents A.2.4 major areas of expos
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Contents A.3.8.2 Social security da
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Contents A.6.4.2 Minimally detectab
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Abbreviations C.2 mEThOdS fOr STATI
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Abbreviations DXA Dual-energy x-ray
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Abbreviations CHS Cardiovascular He
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A.1 A.1 Introduction and overview a
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A.1 A.1 Introduction and overview s
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A.1 A.1 Introduction and overview T
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A.3 A.3 Study design Informed Conse
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A.3 A.3 Study design 6. Since being
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A.3 A.3 Study design the possible d
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A.3 A.3 Study design A.3.5 Collecti
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A.3 A.3 Study design Blood In addit
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A.3 A.3 Study design the anterior n
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A.3 A.3 Study design study. For exa
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A.3 A.3 Study design large-size sto
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A.3 A.3 Study design routinely prep
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A.3 A.3 Study design Subjects who m
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A.3 A.3 Study design A.3.6.3 reliab
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A.3 A.3 Study design In addition, a
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A.3 A.3 Study design Disease Questi
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A.3 A.3 Study design Data routinely
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A.3 A.3 Study design tial misclassi
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A.3 A.3 Study design � The KORA c
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A.3 A.3 Study design Table 3.16: Co
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A.4 A.4 Integrated Data Management
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A.5 A.5 Methods for quality assuran
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A.6 A.6 Planned statistical analyse
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A.6 A.6 Table Planned 6.4: Expected
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A.6 Planned statistical analyses an
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A.7 A.7 Ethical aspects logical/gen
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A.7 A.7 Ethical aspects The more ex
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A.7 A.7 Ethical aspects pants, trav
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A.7 A.7 Ethical aspects Data handli
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A.7 Table 7.2 Availability of ident
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A.7 A.7 Ethical aspects Should bios
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A.7 A.7 Ethical aspects ing finding
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C.1 C.1 Annex: Description of the s
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C.1 C.1 Table Annex: 1: Cluster Des
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C.2 C.2 Annex: Methods for Statisti
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C.2 Table S6.5: Sample size needed
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C.3 References 17. Keil, U., et al.
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C.3 References 50. Benjamin, E.J.,
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C.3 References 85. Calle, E.E. and
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C.3 References 121. Walter, R., D.J
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C.3 References 189. Ghiotto, F., et
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C.3 References 225. Schmidt, C.O.,
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C.3 References 260. Eussen, S., et
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C.3 References 294. McCrae, R.R. an
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C.3 References 327. Lynch, J.W., G.
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C.3 References 360. Mair, C., A.V.
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C.3 References 395. Lesourd, B., Nu
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C.3 References 431. Statistisches B
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C.3 References 462. Bundeszentrale
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C.3 References 494. Rammstedt, B. a
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C.3 References 526. Mack, F., et al
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C.3 References 560. Palatini, P., A
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C.3 References 590. Greenland, P.,
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C.3 References 623. Olin, A.C., et
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C.3 References 658. Pate, R.R., J.R
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C.3 References 691. Zenge, M.O., et
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C.3 References 727. Ryu, O.H., et a
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C.3 References 757. BSI-Standard 10
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C.3 References 790. Davis, C.E., et
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C.3 References 822. Hegenscheid, K.
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