Scientific Concept of the National Cohort (status ... - Nationale Kohorte

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Applicants Applicants Applicants Cluster Bavaria Study center Augsburg Study center Regensburg Cluster Baden-Wuerttemberg/Saarland Study center Heidelberg/Mannheim Study center Freiburg Study center Saarbruecken Cluster North Rhine-Westphalia Study center Essen Study center Muenster Study center Duesseldorf Cluster Saxony/Saxony-Anhalt Study center Halle Study center Leipzig Prof. Dr. Dr. H.-Erich Wichmann PD Dr. Jakob Linseisen Prof. Dr. Dr. Michael Leitzmann Prof. Dr. Iris M. Heid Prof. Dr. Rudolf Kaaks Dr. Karin Halina Greiser II Helmholtz Center Munich (HMGU) Regensburg University (RU) German Cancer Research Center (DKFZ), Heidelberg Prof. Dr. Heiko Becher University of Heidelberg Prof. Dr. Dr. Karin Michels Dr. Claudia Schmoor Prof. Dr. Hermann Brenner Christa Stegmaier Prof. Dr. Karl-Heinz Jöckel PD. Dr. Susanne Moebus Prof. Dr. Klaus Berger Prof. Dr. Hans-Werner Hense University of Freiburg German Cancer Research Center (DKFZ), Heidelberg Saarland Cancer Registry, Saarbruecken University Hospital Essen, University of Duisburg-Essen University of Muenster Prof. Dr. Guido Giani German Diabetes Center Prof. Dr. Ursula Krämer Prof. Dr. Andreas Stang Prof. Dr. Johannes Haerting Prof. Dr. Markus Löffler Prof. Dr. Joachim Thiery Leibniz Research Institute for Environmental Medicine (IUF) Martin-Luther-University of Halle- Wittenberg University of Leipzig and University Hospital Leipzig
Cluster Berlin-Brandenburg Study center Berlin-North Prof. Dr. Tobias Pischon Study center Berlin-Center Study center Berlin- South/Brandenburg Prof. Dr. Stefan Willich Prof. Dr. Peter Heuschmann Prof. Dr. Heiner Boeing III Applicants Max Delbrueck Center for Molecular Medicine (MDC) Berlin-Buch Charité -- University Medical Center Berlin German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) Study support center Dr. Bärbel-Maria Kurth Robert Koch Institut (RKI) Berlin Cluster Lower Saxony/Hamburg/Bremen Study center Brunswick/Hanover Study center Hamburg Study center Bremen Cluster Schleswig-Holstein Study center Kiel PD Dr. Dr. Frank Pessler (temporary) Prof. Dr. Lothar Kreienbrock Prof. Dr. Dieter Flesch-Janys Dr. Nadia Obi Cluster Mecklenburg-Western Pomerania Study center Neubrandenburg Helmholtz Center for Infection Research (HZI) University of Veterinary Medicine Hanover, Foundation (TiHo) University Medical Center Hamburg-Eppendorf (UKE) Prof. Dr. Wolfgang Ahrens Bremen Institute of Prevention Research and Social Medicine PD Dr. Thomas Behrens (BIPS) Prof. Dr. Ute Nöthlings Christian-Albrechts-University Kiel Prof. Dr. Alexander Katalinic University of Luebeck Prof. Dr. Henry Völzke Prof. Dr. Wolfgang Hoffmann Ernst Moritz Arndt University, Greifswald
Page 1: The National Cohort A prospective e
Page 6 and 7: Applicants IV
Page 8 and 9: Executive Summary 2. The National C
Page 10 and 11: Executive Summary 3. Scientific aim
Page 12 and 13: Executive Summary essary to address
Page 14 and 15: Executive Summary 7. Examples for s
Page 16 and 17: Contents A.2.4 major areas of expos
Page 18 and 19: Contents A.3.8.2 Social security da
Page 20 and 21: Contents A.6.4.2 Minimally detectab
Page 22 and 23: Abbreviations C.2 mEThOdS fOr STATI
Page 24 and 25: Abbreviations DXA Dual-energy x-ray
Page 26 and 27: Abbreviations CHS Cardiovascular He
Page 28 and 29: A.1 A.1 Introduction and overview a
Page 30 and 31: A.1 A.1 Introduction and overview s
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Page 34 and 35: A.1 A.1 Introduction and overview m
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Page 46 and 47: A.1 A.1 Introduction and overview A
Page 48 and 49: A.2 A.2. Scientific background and
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A.2 A.2. Scientific background and
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A.3 A.3 Study design ment instrumen
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A.3 A.3 Study design Table 3.2: Des
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A.3 A.3 Study design Table 3.3: Dis
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A.3 A.3 Study design the participan
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A.3 A.3 Study design with a prepare
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A.3 A.3 Study design rural areas, t
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A.3 A.3 Study design A.3.2 Baseline
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A.3 A.3 Study design Modules 70 Int
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A.3 A.3 Study design ovarian carcin
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A.3 A.3 Study design Table 3.5: Spe
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A.3 A.3 Study design depression and
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A.3 A.3 Study design to the extent
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A.3 A.3 Study design ers to vaccina
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A.3 A.3 Study design certain foods)
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A.3 A.3 Study design A short instru
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A.3 A.3 Study design ticipants and
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A.3 A.3 Study design a resting time
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A.3 A.3 Study design index, convent
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A.3 A.3 Study design Although the i
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A.3 A.3 Study design air and then t
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A.3 A.3 Study design hemorrhages (0
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A.3 A.3 Study design genetics of BM
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A.3 A.3 Study design hand grip stre
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A.3 A.3 Study design Project title
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A.3 A.3 Study design diseases in va
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A.3 A.3 Study design associations,
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A.3 A.3 Study design Informed Conse
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A.3 A.3 Study design 6. Since being
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A.3 A.3 Study design the possible d
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A.3 A.3 Study design A.3.5 Collecti
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A.3 A.3 Study design Blood In addit
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A.3 A.3 Study design the anterior n
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A.3 A.3 Study design study. For exa
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A.3 A.3 Study design large-size sto
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A.3 A.3 Study design routinely prep
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A.3 A.3 Study design Subjects who m
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A.3 A.3 Study design A.3.6.3 reliab
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A.3 A.3 Study design In addition, a
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A.3 A.3 Study design Disease Questi
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A.3 A.3 Study design Data routinely
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A.3 A.3 Study design tial misclassi
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A.3 A.3 Study design � The KORA c
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A.3 A.3 Study design Table 3.16: Co
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A.3 A.3 Study design Table 3.17: Co
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A.4 A.4 Integrated Data Management
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A.5 A.5 Methods for quality assuran
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A.6 A.6 Planned statistical analyse
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A.6 A.6 Table Planned 6.4: Expected
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A.6 Planned statistical analyses an
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A.7 A.7 Ethical aspects logical/gen
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A.7 A.7 Ethical aspects The more ex
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A.7 A.7 Ethical aspects pants, trav
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A.7 A.7 Ethical aspects Data handli
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A.7 Table 7.2 Availability of ident
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A.7 A.7 Ethical aspects Should bios
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A.7 A.7 Ethical aspects ing finding
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C.1 C.1 Annex: Description of the s
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C.1 C.1 Table Annex: 1: Cluster Des
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C.2 C.2 Annex: Methods for Statisti
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C.2 Table S6.5: Sample size needed
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C.3 References 17. Keil, U., et al.
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C.3 References 50. Benjamin, E.J.,
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C.3 References 85. Calle, E.E. and
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C.3 References 121. Walter, R., D.J
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C.3 References 155. Ross, R., Ather
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C.3 References 189. Ghiotto, F., et
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C.3 References 225. Schmidt, C.O.,
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C.3 References 260. Eussen, S., et
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C.3 References 294. McCrae, R.R. an
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C.3 References 327. Lynch, J.W., G.
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C.3 References 360. Mair, C., A.V.
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C.3 References 395. Lesourd, B., Nu
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C.3 References 431. Statistisches B
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C.3 References 462. Bundeszentrale
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C.3 References 494. Rammstedt, B. a
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C.3 References 526. Mack, F., et al
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C.3 References 560. Palatini, P., A
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C.3 References 590. Greenland, P.,
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C.3 References 623. Olin, A.C., et
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C.3 References 658. Pate, R.R., J.R
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C.3 References 691. Zenge, M.O., et
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C.3 References 727. Ryu, O.H., et a
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C.3 References 757. BSI-Standard 10
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C.3 References 790. Davis, C.E., et
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C.3 References 822. Hegenscheid, K.
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