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Journal Thoracic Oncology

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Abstracts <strong>Journal</strong> of <strong>Thoracic</strong> <strong>Oncology</strong> • Volume 12 Issue S1 January 2017<br />

POSTER SESSION 1 - P1.08: SURGERY<br />

MINIMAL INVASIVE SURGERY –<br />

MONDAY, DECEMBER 5, 2016<br />

POSTER SESSION 1 - P1.08: SURGERY<br />

MINIMAL INVASIVE SURGERY –<br />

MONDAY, DECEMBER 5, 2016<br />

P1.08-048 COMPARISON OF PULMONARY FUNCTION AFTER<br />

ROBOTIC-ASSISTED VIDEO-THORACOSCOPIC LOBECTOMIES VS<br />

SEGMENTECTOMIES<br />

Maria Echavarria 1 , Anna Cheng 1 , Frank Velez 1 , Emily Ng 1 , Carla Moodie 2 , Joseph<br />

Garrett 2 , Jacques-Pierre Fontaine 2 , Eric Toloza 2<br />

1 University of South Florida, Tampa/FL/United States of America, 2 <strong>Thoracic</strong><br />

<strong>Oncology</strong>, Moffitt Cancer Center, Tampa/United States of America<br />

Background: Lobectomy is the standard surgical procedure for early stage<br />

lung cancer, but sub-lobar resection is being debated. We compared<br />

pulmonary function after robotic-assisted video-assisted Thoracoscopic<br />

(R-VATS) segmentectomy versus lobectomy; comparison using robotic<br />

instruments hasn’t been published. Methods: We retrospectively analyzed<br />

prospectively collected data from 251 consecutive patients who underwent<br />

lobectomy (N=208) and segmentectomy (N=43) via R-VATS by one surgeon.<br />

Unpaired Student’s t-test and Chi-square tests were used to determine<br />

statistical significance(p≤ 0.05). Majority of patients had no prior lung<br />

surgery. We used “Predicted(PFT)=Preop(PFT)x(1-(Segments x 0.0556))”,<br />

where 0.0556=1seg/18seg. For patients with prior resections, the number of<br />

segments previously resected was taken into account(1seg/(18-Prior<br />

resection)). Results:<br />

P1.08-049 CT GUIDED LABELING WITH INDOCYANINE GREEN OF<br />

SMALL LUNG NODULES FOR SUBLOBAR RESECTION UTILIZING<br />

ROBOTIC ASSISTED THORASCOPIC SURGERY (RATS)<br />

K Adam Lee 1 , Lee Fox 2 , Andrew Hall 2 , Vincent Turiano 2<br />

1 <strong>Thoracic</strong> Surgery and Lung Center, Jupiter Medical Center, Jupiter/FL/United States<br />

of America, 2 Radiology, Jupiter Medical Center, Jupiter/FL/United States of America<br />

Background: Localization of deep and small pulmonary lung nodules<br />

undergoing a wedge or sublobar resection may be challenging during<br />

thoracoscopy, and may necessitate greater resection or conversion to<br />

thoracotomy. Particularly in robotic surgery, with the absence of tactile<br />

feedback. Percutaneous CT guided Indocyanine Green injection provides<br />

a means to pinpoint these nodules. Methods: A retrospective study of 40<br />

consecutive patients who underwent preoperative CT-guided localization of<br />

solitary pulmonary nodules with ICG. Nodules < 15mm were 21/40 (52.5%), <<br />

20mm 30/40 (75%), and < 30mm 38/40 (95%). A 22-gauge spinal needle (BD,<br />

NJ) or Chiba needle (Cook, IA) was positioned into or adjacent to the nodule.<br />

0.4cc Indocyanine Green was injected and the inner stylet withdrawn. The<br />

Xi daVinci robot (Intuitive Surgery, CA) was docked and the firefly filter of<br />

the 8mm camera was activated, and the nodule illuminates in a flouresence<br />

green color. A wedge or sublobar resection was performed, with progression<br />

to lobectomy when indicated. Results: CT guidance successfully localized<br />

the nodules in 100% of 40 patients employing this technique. Success was<br />

measured in nodule illumination as seen by the surgeon upon activation of the<br />

camera filter and confirmed on frozen and permanent section by pathology.<br />

Initial wedge resection for diagnosis prior to lobectomy and sublobar<br />

resection for decreased PFTs or decrease cardiac function were performed<br />

by Robotic Assisted Thoracoscopy (RATS). There were no conversions to<br />

thoracotomy. Diagnosis were adenocarcinoma in 18 patients (45%), squamous<br />

cell carcinoma in 7 patients (17.5%), carcinoid in 1 patient (2.5%), metastatic<br />

in 8 patients (20%), and benign in 6 patients (15%). There were no 30 or 90<br />

day mortalities. A chest tube reinsertion in one patient for pneumothorax.<br />

Economically the cost for the vial of ICG is $79.56 compared to a fiducil marker<br />

at a cost of $128.00. <strong>Thoracic</strong> Surgery has access to CT scanners, without an<br />

extra cost, electromagnetic navigation systems come with significant added<br />

costs. Conclusion: Percutaneous CT guided labeling with ICG is quick and<br />

economical for the localization of small and deep nodules undergoing RATS<br />

wedge or sublobar resection. This technique may be supportive in preserving<br />

lung parenchyma and reduce the need for conversion to thoracotomy,<br />

maintaining minimal invasive thoracic surgery, especially where palpation or<br />

tactile feedback is absent.<br />

Keywords: pulmonary nodules, sublobar resection, Minimal Invasive thoracic<br />

surgery, CT guided labeling<br />

POSTER SESSION 1 - P1.08: SURGERY<br />

MINIMAL INVASIVE SURGERY –<br />

MONDAY, DECEMBER 5, 2016<br />

P1.08-050 VATS LOBECTOMY IN LOCALLY ADVANCED NSCLC: A<br />

SINGLE CENTRE EXPERIENCE<br />

Davide Tosi, Lorenzo Rosso, Paolo Mendogni, Alessandro Palleschi, Ilaria<br />

Righi, Matteo Montoli, Francesco Damarco, Mario Nosotti<br />

Fondazione IRCCS Ca’ Granda Policlinico, Milan/Italy<br />

Preoperative FEV1(%) and DLCO(%) were statistically significant between the<br />

two groups. Also, FEV1 and DLCO were lower in segmentectomy patients. As<br />

expected, predicted changes between preoperative and postoperative values<br />

were significant. Predicted post-operative FEV1 and DLCO did not show any<br />

significant difference between the two groups. Conclusion: While preoperative<br />

PFTs were significantly lower in segmentectomy patients compared<br />

to lobectomy patients, predicted post-operative PFTs do not differ<br />

significantly. Predicted changes for FEV1 and DLCO are significantly less in<br />

segmentectomy. Thus, negate the difference in pre-operative PFTs. In<br />

conclusion, R-VATS segmentectomy preserves lung function and may be<br />

considered a viable alternative<br />

Keywords: Robotic surgery lobectomy segmentectomy<br />

Background: VATS lobectomy has become the gold standard in early<br />

stage lung cancer treatment, but its role is still debated in case of locally<br />

advanced disease (tumor larger than 5 cm, chest wall involvement, hilar<br />

adenopathy, need for sleeve resection). The aim of this study was to evaluate<br />

the main differences between VATS lobectomy performed for early stage<br />

NSCLC and the ones performed for locally advanced disease. Methods: We<br />

retrospectively analyzed patients that underwent VATS lobectomy for tumor<br />

resection in our centre, from July 2011 till December 2015. Patients included<br />

in the study were similar for demographic characteristics and for number of<br />

resected lymph nodes. We performed 136 VATS lobectomies: 124 following<br />

standard indications (group A); 12 following “extended” indications (group B).<br />

Group B is composed by: 3 VATS sleeve lobectomy; 3 VATS lobectomy followed<br />

by limited chest wall resection (hybrid technique); 6 VATS lobectomy for<br />

NSCLC larger than 5cm. We evaluated the conversion rate to open surgery, the<br />

intraoperative blood loss, the operation lenght, the chest drain maintenance<br />

and the length of hospitalization. Results: Intra-operative conversion rate<br />

was higher in group A than in Group B, but not statistically different (13,7%<br />

vs 9%; p>0,05). No differences were detected in the intraoperative blood<br />

loss. Instead we observed differences in terms of operation length, of chest<br />

drain maintenance (4,8 vs 7,4 days; p

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