European Journal of Scientific Research - EuroJournals

Toxicokinetic Studies of Cadmium and Zinc in Goats Following Intratracheal and
Intravenous Administration of Particulate Matter 351
Figure 1: Plot of Cr concentration against times for intratracheally and intravenously treated goats
Figure 2: Plot of Zn Concentration against times for intratracheally and intravenously treated goats
Tissue kinetics of elements present in dusts
The mean concentrations of chromium in the tissues at 72 hours for intratracheally treated goats were
0.48±0.02µg/g for lungs,0.45±0.06µg/g for liver, 0.44±0.02µg/g for heart and 0.44±0.05µg/g for
kidneys (Figure 3). For the intravenously treated goats, at 72 hours after dust treatment, tissue
concentrations were 0.43±0.04µg/g for lungs, 0.47±0.03µg/g for liver 0.46±0.04µg/g for heart and
0.51±0.02µg/g for kidneys (Figure 4). The concentrations of chromium in the tissues were observed to
show a continuous decrease and at 21 days, the concentrations of elements in the tissues dropped close
to pre-treatment levels