3+4+Supplementum/2012 - Společnost pro pojivové tkáně

figure 2 shows rigid plate fixation of
diaphysis of the left femur, the lateral and
medial cortical femoral defects (that arose
after one stage “Z” lengthening) that are
filled up with Si-CAP (Actifuse), i.e. novel
synthetic, porous biomaterial with proved
very good osteointegration.
figures 3a, B. X-rays of the left femur
(in AP and lateral projections) 2 months
after surgery proved incipient healing of
osteotomy and remodelling of applied
Si-CAP (Actifuse).
figures 4a, B. X-rays of the left femur
(in AP and lateral projections) 10 months
after surgery showed healing of osteotomy
and progressive remodelling of Si-CAP,
some granules were still recognizable especially
in the proximal lateral defect of
corticalis (undesirable shielding effect of
the rigid plate). Restoration of the medulla
canal is not finished, yet.
The step by step treatment was monitored
by repeatable antropological meas-
Fig. 2
350 14 th Prague-Sydney-Lublin
urement. The comprehensive treatment
led to an increase of predicted adult high
only by 8.4 cm. Description of this case
shows the most common barriers and complications,
which usually accompany the
lengthening operations. Observed growth
retardation was presumably caused by
stress of the patient during lengthening
procedures and because of growth hormone
(GH) therapy that was indicated
by endocrinologist with the aim to stimulate
bone remodelling during and after
lengthening. GH therapy lead to premature
growth plates closing.
The global thickening of the bone
tissue (considering the integral, overall
view of the tissue) includes the sequence
(chain) of biomechanical-chemical processes
(i.e. biochemical reactions and steady
states) whose result is the increase of density
in the bone tissue (in its examined
element). A typical feature of the process
of bone tissue thickening (in its volume