HYDROPXRICAru)II'M SYI{DROME (ANGARA DISEASE) IN ...
HYDROPXRICAru)II'M SYI{DROME (ANGARA DISEASE) IN ...
HYDROPXRICAru)II'M SYI{DROME (ANGARA DISEASE) IN ...
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DEVErcPMANTOF HETAROTYf IC VACC<strong>IN</strong>EACA<strong>IN</strong>ST HTS ASSOCIATED<br />
AVL{N ADf,NOVIRIJS<br />
tr uN respomc of broih. cltuks ftlninislered v.tious HPS viccins imluding AAV-<br />
PARC-l v(cine w6 deldin.d<br />
Vrein.lion Tn*: Prlga 6f vtnous vnrl rntibodi6 in en ans usins mS @i.c and<br />
puriied AAV-PARC I !d@in. vas lened h btoilc$ (T.bl. Vll- I ).<br />
Senrm samples froo btds vaccindl.d with liq homoSenate ftom freld oulbr€ks<br />
indi&r.d $c pte@ of dlibody lgiitst CAA ind Ro viN Ho*vd. no briboni6<br />
aBaitur orgmisms like IBDV, CA,A' NrDV, IBV or R6 viM we.e dd.clail. in rhl sE of<br />
chicks inoorlrted with rh. punlied A V isolat PARC-I (ldle vll_l) Th. presenr work<br />
indiBted rhat AAv isolat. PARCI alonc i3 c.pable ofolsin8 HPS in chicb. Ho*M, thc<br />
eldier $udiB had suggc$.d $me tole of IBDV or Rco vitos it occureo@ of HPS discrsc<br />
by AAV (McFeiian, 1939i Mufter e/ d/, 1939) Th. lact thal unds field condiions,<br />
parhos{t cau3ing th.s. di!.e niehl pl.y sone rc|. in p.€ipitation or .Sg.valing rh.<br />
snuodon ii rhc fa€ ofan ou$;ak.<br />
Atrtihody Tilr.s: Va@inalion againlt isolates PARC_|, AD_4, AD'3, LH, and llPS,<br />
provoked r r.rihody production wiihin on. wc.k and ponvaeinalion (PV) titr.s of intibody<br />
w.e hiBh6r on 3rd wak PV Gable V!l-2) Sinihrly 6.din3: wer. rtpon.d by Ddjou.<br />
workers(Afzd.ndAhm0d,l99o;Ahn.drraa,l990iM8hloorerar, 1994) lnomparison<br />
ro odet vaccina|od rel.tiv.ly ni8ler DtA lfie (GMT 2 I I I ) in AD-4 vtccidled bnd! w.,<br />
obsetued ar 3 weeks Pv How, i, drrc d4lin d.n.r4 se€*s PV. Th. DIA tirte of 16<br />
was coBid.rcd ar nes.tiv.. Alt th. control bn& r.h.in d ncgdi!. fot HPs mtibodv<br />
$roushoul the dpein.ntd p.riod Tne lntibody dlr. in AD-4 tdcci!.ted bnd, w.s<br />
signifidi y hiehs (P < 0.05) thtn lhe antihody tilr6ofbirds vaeinaren wnhPARC_I. AD-<br />
3, LH and llPs i$lar6 (Fig \rll-l) All $c v!@imtn grcup! (Al At) hid qune high (P <<br />
0 05) serun rrtibody rires &gdnsl lydropticedun ausnS rgenl<br />
lr is *onh expenm.nl.tion whed.r lhc oddo d.clirc in Dla tntibody fttca an.r 4"<br />
PV wceh @uld be overome by inodl ins oil_emuhion HPSV vteites
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