HYDROPXRICAru)II'M SYI{DROME (ANGARA DISEASE) IN ...

Chapter 4
EXPENMDNT'.1
Clinic.l..d nerept fbdillt
RESULTS AND DISCUSSION
ISOLATION AND PNOTAGATTON OF HPS AGDNT
Inf€rcd bnds lookcd dcpre$, hd tomcd md dropped fqlh.u, lhen h.ad lowered
wnh baks restins o. rhe lilr4, r.d bn& v.r. reluctlnl to hot. Th.y huddted .round the
sr@ of ha| showed Mo.di. lnd cxp.ric.c€d diffr@lry in nov.lMts. 506. of dE
iildcd chick had looe droppingr, sr..nnh b y.llowish &d chalky p.sred v€nt! A l.N
birds indi@ted difncuty in rcspinrio. Houd.r, $. plere of dqd bnds wi! rh. onlv
sisniticant sigo of rhc HPS in ccndi 0oclis. Th. inf@ted bitd, had ncgligible Ecove.y tate
Bnds, which died cfter HIS as.nt inocul0tion or @e contidded noribund, had
onsislcnt and chr..ct.rinic l6ioN Gougt A-Er Tahl.l-l). ftc p.ric.rdia! ,rc h8d cl@,
ambcr or eraw coloured gol inous nuid, which oe.sur.d dpDroximilcly 5_20 ml (Fig l)
L.sions ofi.rl.d hydop.nqrdiun wrc F. in 3Cr'/. ol$. ddd bnds Ttc lt.n @E
hi$hrpa a.d nlbby, p.t.chial md .cchyoolic h0.6onhages wcc noted in thc hsrt
nu$uhlure (Fis 2) The@ w.s engesiion md oenm ii the lungs, pil. 8nd swollen kidnevs
(FiB lt, fllar8.d dd hemoiih!&c [vd {fig 4}. Thym3, $l*n.nd 44,1 tonsih wec
.drllor thu tha uninrecr.d bird!. Mos ofrhc burs w.r nyp€drophi.d (Fjs 5) ind @rc
bnd. hld .tophi.i burse No leiont co d b. @.d.n in thc bmin tilru.
Multiple coasulitiv. n@rolic fooi ol varyins siz4, vaoolar dnd fany d.g.i.t oB
and pdivlshr ii6lt6don ol mo.otuclq{.lB wrc obed.n i. rhc lis of inldtcd bnds
M..y ofrhe dea.n.6lios h.pttoqles co.tan.d l6se round baophilic inkmuclar inclueon
bodi.s (Fig. 6) Kidney tissue indidt€d pdlnchymlo$ d.gedNtion oa tuhular . pilh.liun.
&d oGioml h.d6.rh.g.5 i. lh. intdditiol tistuB Ctrdiac lis.s had l.sioc suuh a
myooo.di.l desen.rltio., o.d.m. Md nononucld cell infiltalion (Fig. ?), coDsestion or