HYDROPXRICAru)II'M SYI{DROME (ANGARA DISEASE) IN ...

nds in 0ocks is th€ onty signilionr lign ofth. HpS Tonico i, and tam.ness in tew bnds
have al$ been obsfr.d Th. srr.$.d bnds oft.n di. {trf0n, lgss: Sbah e/ a/, lgss)
Monrlty n higbe. il youngd bi ds qs conplr.d ro rhc. in otd .ge sroops (Khan r/ 41,
r988)
The most con$l.nt .nd charactcrktic t4ion r.ron.d & nccropsy 6 rhe presen@ ol.
ol@r, amber o, sraw color.d gchtinous nujd, approximrtety 9-20 nt, in rlE perioardi.l sao.
The h6n is bisshdrcn cnd U.bby (Khrn d/ d/, r98srAiju6.rul, tg8giChema c/41,
1989), pe!*hial and e€hymoric h..Dorh!s.r !pp6r in rhc hean muscutarure There is
coneston rnd a vori0bl. degrc. ofo.d.o! i. th.lu,gs, pde bd swo en kidneys, enrdged
a l h8modhagic livcr Multipte @gd ivc nccrotic f@iof wrying sizes, vicuolar ud tally
d€gereBrjons .Dd pdiv|s|f in6l|oiion of mononuctdF@tk vs. pr.s.nl in rbe tive6 of
af4r.d binir Matry of rhc d.gae..ri.g hcp cyr.s conrlined tarse round baephitic
i.rrnuclar inclusion bodi.s Kidn.y tis6 hld prMctrF,rous dcs.ftadon of tubutai
epith.liom, ind o@sio..l hamorhlg.s in rhc inrcrslnid rissucs c|rdiac rises had t*io6
includi.g my@dial d.gcndtion, o.dma ed tunonucrar c.tt infiht|io,\ 6nge$ion of
blood Bsek, o.d.m. .nd sw.lling ot lscuhr mdorhctiuD oed.ma, consdion ,nd
inoanturo.y cetlul,r infihrario. an rh. h,n$ v.,. pr.!.nr. Mic.oscop,c ch.nses,n rhe burs
oa Fabnoius wer. nor conrir.nr Mqt oflha burs h.d hy!.nrophy *hite bu,se were
arroph'edinfewcas6{Kh!w.j..r.l,r98BiAnjum4z/,1989;Annadera/,l939iMun*r
srar,l93qAhmad,l99O)
The tt?S virus(HPS\, tu ben isot6r.d by son.workersm hish rires trom tiver of
afrected bnds where n ca6cd inrn.ucle{r indr3ion bodia jn ihe beparocrres (Chena c/ d/,
1989, Ahmad, 1990) Thc HPS h.s be$ $roccstu y reproduced in strscepiible chickens b)'
$bcut.reolsinocularionofl5-20/.sulpc.sionoftivqtillrarc(Mun.s4ot,l9s9).
Hydrop€ricardiun is a coftpt.x syndrom. catrscd hy a 0tr,nber of iMorious
oicrooreanihs plus rh. inteBction of..vno.mcn$1. ,uridon.t, and olher pmdy define!
facroG (J0fery, 1988) Wlitc evqit nicrobiotogi@t ag.nrs cin niriale this disae. virus6