Genes IX Benjamin Lewin - PortuguesBR

REFERÊNCIAS 455
11:11 O Sistema Modelo cpX Revela como um
DNA de Fita Simples É Gerado para a
Replicação
Anigos de Pesquisa
Dillingham, M. S., Wigley, D. B., and Webb, M . R. (2000).
Dcmonsrrarion of unidirecrional single-srranded DNA
translocation by PerA helicase: measuremem of srep
size and Lranslocation speed. Biochemistry 39, 205-212.
Singleron, M. R., Sawaya, M. R., Ellenberger, T., and Wigley,
D. B. (2000). Crystal strucrun: of17 gene 4 ring
helicase indicares a mcchanism for sequenrial hydrolysis
of nucleorides. Ce!! 101, 589-600.
lf:M A Holoenzima da DNA Polimerase
Possui três Subcomplexos
Referência
johnson, A., and O 'Donnell, M. (2005) . Cellular DNA
rcplicascs: componems and dynamics ar the replicarion
fork. Annu Rev Biochem. 74, 283-315.
A rtigo~ de Pe~quiS.'t
Srudweli-Vaughan, P. S. and O 'Donnell, M. (1991). Constirurion
of the rwin polymerase of DNA polymerase
111 holoencyme.]. BioL Chem. 266, 19833-19841.
Srukenberg, P. T., SrudweU-Vaughan, P. S., and O'Donnell, M .
(199 1 ). Mechanism o f the sliding bera-clamp ofDNA polymerase
111 holoen7.)'111e.J Biol Chen1. 266, 11328-11334.
ll:llel A Braçadeira Controla a Associação da
Enzima Cerne com o DNA
Revisões
Benkovic, S. J., Valenrine, A. M., and Salinas, F. (2001).
Replisome·mediared DNA replicacion. Annu. Rev. Bíochem.
70, 181-208.
Davey, M.]., Jeruzalmi, D ., Kuriyan, J., and O'Donnell, M .
(2002). Morors and swirches: AAA+ machines wirhin d1e
rcplisome. Nat. &v. MoL CelL BioL 3, 826-835.
Anigos de Pesquisa
Bowman, G. 0 ., O'Donnell, M., and Kuriyan, J. (2004).
Strucrural analysis o f a eukaryoric sliding DN A clamp·
damp loader complex. Narure 429, 724-730.
Jeruzalmi, O., O'Donnell, M., and Kuriyan, J. (2001).
Crysral srrucrure o f the processiviry clamp loader gam·
ma (gamma) complex of E. co/i DNA polymerase III.
c~//106, 429-441.
Kong. X. P., Onrust, R., O'Donnell, M., and Kuriyan, J.
(1992). Three-dimensional srrucrure of me beca subunir
of E. coli DNA polymerase III holoenzyme: a sliding
ONA clamp. c~L/69, 425-437.
11:111 A Coordenação da Síntese das Fitas
Contínua e Descontínua
Artigo de Pesquisa
Dervyn, E., Suski, C., Daniel, R., Bruand, C., Chapuis, J.,
Errington, ]., Janniere, L., and Ehrlich, S. D. (2001).
Two essenrial DNA polymerases at rhe bacrerial replication
fork. Scienc~ 294, 1716-1719.
lf:lrj Os Fragmentos de Okazaki São Unidos
por uma Ligase
Revisão
Liu, Y., Kao, H. I., and Sambara, R. A. (2004). Flap endonuclease
1: a central componenr of DNA metabolism.
Annu. Rev. Biochem. 73, 589-615.
II:IQ DNA Polimerases Eucarióticas
Distintas Realizam a Iniciação e a
Elongação
Revisões
Goodman, M. F. (2002). Error-prone repair DNA polymerases
in prokaryotes and eukaryores. Annu. Rev. Biochem.
71, 17-50.
Hubscher, V., Maga, G., and Spadari, S. (2002) . Eukaryotic
DNA polymerases. Annu. Rev. Biochem. 7 1, 133-
163.
Kaguni, L. S. (2004). DNA polymerase gamma, the mítochondrial
replicase. Annu. &v. Biochem. 73, 293-320
Arrigos de Pesquisa
Karthikeyan, R., Vonarx, F.. J., Srraffon, A. F., Simon, M.,
Faye, G., and Kun1., B. A. (2000). Evidence from mutational
specificiry studies chac yeasr DNA polymerases
delta and cpsilon replicate diffcrent DNA strands
ar an imracellular replicarion fork. ]. Mo!. Bio!. 299,
405-4 19.
Shiomi, Y., Usukura, J., Masamura, Y., Takeyasu, K.,
Nakayama, Y., Obuse, C ., Yoshikawa, H., and Tsurimoto,
T. (2000). ATP-dependent srrucrural change of
che eukaryotic clamploadcr pro rcin, replication facror
C. Proc. Natl. Acad. Sei. USA 97, 141 27-14132.
Waga, S., Masuda, 'L, 'làkisawa, H., and Sugíno, A. (2001).
DNA polymerase epsilon is requircd for coordinatcd and
efficiem chromosomal DNA replicacion in Xenopus egg
exrracrs. Proc. Natl Acad Sei. USA 98, 4978-4983.
Zuo, S., Bermudez, V., Z hang, G ., Kelman, Z ., and
Hurwirz, J. (2000). Srrucrure and acriviry associared
with multi pie forms of S. pombe DNA polymerase delta.).
Biol. Chtm. 275, 5153-5162.
li:ltJ O Fago T4 Possui seu Próprio Aparato
de Replicação
Anigos de Pesquisa
Ishmael, F. T., AUey, S. C., and Benkovic, S. J. (2002). Assembly
of rhe bacteriophage T4 helicase: archirecrure
and sroichiomerry of rhe gp41-gp59 complex. ]. BioL
Chem. 277, 20555-20562.
Salinas, F., and Bcnkovic, S. J. (2000). Characrerization of
bacreriophage T4-coordinared leading- and laggingstrand
synthesis on a minicircle subsrrare. J>roc. Nat!.
Acad. Sei. USA 97, 7196·7201.
Schrock, R. D. and Alberrs, B. (1996). Processiviry o f rhe
gene 41 D NA helicasc ac rhc bacte riophage T4 DNA
rcplication fork.). Biol. Chem. 271, 16678-16682