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Protocols - Hemorio

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TREATMENTO AND IN<br />

ADULTS AT ANY AGE<br />

REINFORCEMENT ON<br />

EVERY FALL<br />

- Hepatitis B (HbsAg, anti-Hbc and anti-Hbs (-) with a timeout < 3 m)<br />

- Pneumo 23 in non-vaccinated patients and/or that who will be submitted to splenectomy<br />

with 5-year reinforcement .<br />

- Anti-Haemophyllus influenza in non-vaccinated.<br />

- Influenza (flu) – annually in the fall<br />

- Anti-tetanus every 10 years, specially in patients with leg ulcers<br />

- Influenza vaccine<br />

INFECTION: In children less than 5 years old, the major cause of death from septicemia and meningitis is<br />

due to Streptococos pneumoniae and Haemophyllus influenza infection. Infections may precipitate vasoocclusive<br />

crisis and anemia exacerbations, by erythropoietic suppression or hemolysis .<br />

ANTIBIOTICS PROFILAXY:<br />

ORAL PENICILLIN V (PEN-VE-ORAL)<br />

- Initiated at the moment of the diagnostic<br />

- Maintained until 5 years, up to reinforcement of pneumococcal vaccine<br />

- Prophylaxis must be taken in consideration according to each case on elderly patients<br />

- Up to 10kg or 1 year = 1.5ml V.O. 12/12h<br />

- to 1year from 3 years = 2.5ml V.O. 12/12h<br />

- >3 years = 5ml V.O. 2x day<br />

- PENICILLIN BENZATHINE<br />

- In case of gastric intolerance, noncompliance with the treatment with oral penicillin or impossibility of oral<br />

penicillin (approximately 50.000 U/Kg)<br />

- 300,000 IU – patients weighting < 10 Kg, IM every 3 weeks<br />

- 600,000 IU – patients from 10 to 20 Kg, IM every 3 weeks<br />

- 1,200,000 IU – patients weighting > 20 Kg, IM every 3 weeks<br />

- ERYTHROMYCINE<br />

- In case of penicillin allergy<br />

- Dose: 20 mg / kg / day divided twice a day<br />

CONDUCTION IN THE INFECTIOUS PICTURE<br />

- Thoracic RX<br />

- Complete blood test + VHS + Ret + Ptn C-Reactive<br />

- Biochemistry (TGO, TGP, LDH, bilirubins, urea, creatinine)<br />

- SAE + Urine culture + Blood culture<br />

- Pulse oximeter<br />

- 12-hour observation<br />

HOSPITALIZATION INDICATIONS (AT LEAST 1 FROM BELOW):<br />

- Major decrease of general state<br />

- Hypotension<br />

- Dehydrated or peripheral malperfusion<br />

- Oximetry Evaluation (STA) < 80% of saturation or experienced drop > 5% from baseline value<br />

- Pulmonary infiltrate<br />

- Leukocyte > 30000 or < 5000 / mm 3<br />

- Platelet Count < 100000 / mm 3<br />

- History or similar scene with S. pneumoniae infection<br />

10

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