Protocols - Hemorio

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RESPONSE CRITERIA Full Response Absence of monoclonal protein in the serum and urine by Immunofixation < 5 % of Plasmocyte at MO ( myelogram and BMB) No increase in the size and number of lithic injuries Disappearance of plasmacytoma of soft tissues Partial Response > 50 % of decrease in the serum monoclonal protein Decrease in the excretion of mild chains in the urine in > 90% or to < 200mg/24 hours Non-secretor myeloma decrease > 50% of plasmocytes at MO Decrease > 50% at the soft tissues plasmacytoma No increase in the size and number of lithic injuries Minimum Response Decrease of 25 to 49% of serum monoclonal protein 50 to 89% of decrease at the excretion of the mild chains in the urine (>200mg/24h) Non-Secretor Myeloma 25 to 49% of decrease at the plasma cells of MO 25 to 49% of decrease in the size of soft tissues plasmacytoma No increase in the size and number of lithic injuries 146
TREM Protocol Low Risk or between 60 and 70 years old Self-TMO (collection to 2 TMO) Eligible to TMO Dexamethasone + TalidomideX4 Biphosphonate AAS Risk Stratification 147 High Risk Does it have a donor? RC or VGPR? Yes No Yes No Self-TMO Self-TMO Maintenance with Thalidomide D100 of TMO Progression 2 nd Self-TMO Mini-Alo TMO Self-TMO Maintenance with Thalidomide D100 of TMO Maintenance with Thalidomide D100 of TMO 2 nd Self-TMO Progression Progression or VGPR Maintenance with Thalidomide D100 of TMO Protocol with Bortezomib Protocol with Bortezomib
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PROTOCOLS INSTITUTE OF HAEMATOLOGY
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COORDINATION AND REVISION Clarisse
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SUMMARY: PART I - CLINICAL PROTOCOL
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1.INICIAL CLINICAL EVALUATION SICKL
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TREATMENTO AND IN ADULTS AT ANY AGE
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SPLENECTOMY - INDICATIONS: (1) CHIL
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OUTPATIENT TREATMENT: It is based o
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ASPIRIN AND NSAID PARACETAMOL OPIOI
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CONDUCTION: - Hospitalization - Com
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ONE, TWO-DIMENSIONAL DOPPLER ECHOCA
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Hemianopsia Homonymous deficit of v
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TREATMENT OF CONVULSIVE EPISODES -
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INITIAL ATTENDANCE TO PREGNANT WOME
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- It may occurs acute thoracic synd
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3 Diet with potassium restriction 4
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MICROALBUMINURIA Screening Patients
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RECURRENCE OF PRIAPISM: - Pain Trea
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SPECIAL CARES DEFERASIROX - The use
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TREATAMENT: DRUG Hydroxiurea (hard
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MAJOR AND INTERMIDIATE THALASSEMIA
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HEREDIRATY SPHEROCYTOSIS CLINICAL E
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G6PD DEFICIENCY INITIAL EVALUATION
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LABS EXAMS TO DIAGNOSE APLASTIC ANE
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SELFIMMUNE HEMOLYTIC ANEMIA CONCEPT
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2. Splenectomy: Vaccinate 14 days b
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IMMUNE THROMBOCYTOPENIC PURPURA LAB
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THROMBOTIC THROMBOCYTOPENIC PURPURA
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HEMORRHAGIC SYNDROME INTRODUCTION H
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MULTIDISCIPLINARY FOLLOW-UP OF HEMO
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LYOPHILIZED CONCENTRATES: They are
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TABLE 2: REPLACEMENT THERAPY TO PER
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CONDUCTION IN CONFIRMED INTRACRANIA
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Severe CET with neurological change
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PHARMACOKINETICS OF CLOTTING FACTOR
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INHIBITORS CLASSIFICATION The inhib
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- Extended surgeries require increa
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CLINICAL DIAGNOSIS: According to In
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DDAVP TEST The “test dose” must
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TREATMENT OF BLEEDING SITUATIONS SI
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TABLE 6 - REPLACEMENT THERAPY IN LE
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• Primary prophylaxis: controvers
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CLINICAL AND LABORATORIAL FOLLOW-UP
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MYELODISPLASIC SYNDROME LABORATORIA
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If EPO < 500 mU/ml : EPO (8000U 3x/
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ACUTE MYELOID LEUKEMIA LABORATORIAL
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LMA LMA M3 - non-M3 LMA Protocol LM
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Key: Volunteer to aggressive treatm
Page 96 and 97: Acute Promyelocytic Leukemia Transf
Page 98 and 99: BMP LMA IN CHILDREN AND TEENAGERS
Page 100 and 101: Ara-c dose reduction by age: Age in
Page 102 and 103: ATRA RECOMMENDATION: ATRA is starte
Page 104 and 105: - venous hydration - leukapheresis
Page 106 and 107: POLYCYTHEMIA VERA LABORATORIAL TEST
Page 108 and 109: TREATMENT - 2nd LINE - Indicated fo
Page 110 and 111: ACUTE LYMPHOID LEUKEMIA LABORATORIA
Page 112 and 113: RE-INDUCTION Phase I (weeks 1-4) -
Page 114 and 115: Cycles 2, 4, 6, 8 - Methotrexate 20
Page 116 and 117: PHASE 2 Infusion CPM in 1 hour 1000
Page 118 and 119: CURATIVE RADIOTHERAPY of CNS < 1 ye
Page 120 and 121: CHRONIC LYMPHOCYTIC LEUKEMIA LABORA
Page 122 and 123: fludarabine 25 mg/m VENOUS 2 D1-D3
Page 124 and 125: TRICHOLEUKEMIA LABORATORIAL TESTS -
Page 126 and 127: - age >45 years old - leukocytosis
Page 128 and 129: - Leukemia / T-Cell Lymphoma in Adu
Page 130 and 131: INDICATIONS FOR THE TREATMENT: Symp
Page 132 and 133: 1 st line Chemotherapy R- CHOP (21
Page 134 and 135: CODOX- M/IVAC Cycles 1 and 3 Cyclop
Page 136 and 137: BLOCK A DEXA VO/IV 10 mg /m2 in 3 d
Page 138 and 139: - Surgical treatment is only indica
Page 140 and 141: LEUKEMIA / T-CELLS LYMPHOMA OF THE
Page 142 and 143: HN2 or PUVA (similar to the located
Page 144 and 145: MULTIPLE MYELOMA LABORATORIAL TESTS
Page 148 and 149: WALDENSTRON MACROGLOBULINEMIA LABOR
Page 150 and 151: − If HLA-identical related donor
Page 152 and 153: TREATMENT PROTOCOL - ACUTE MYELOID
Page 154 and 155: TREATMENT PROTOCOL - MULTIPLE MYELO
Page 156 and 157: Post-autologous transplantation pro
Page 158 and 159: PART II - TRANSFUSIONAL PROTOCOLS A
Page 160 and 161: PRESERVATION AND CONSERVATION: The
Page 162 and 163: TRANSFUSION OF RED BLOOD CELLS, PLA
Page 164 and 165: FORMAL CONTRAINDICATIONS TO THE PLA
Page 166 and 167: 1 - TRANSFUSION OF FROZEN FRESH PLA
Page 168 and 169: COMMUNICATION FORM OF CRYOPRECIPITA
Page 170 and 171: Volume to be = changed (*) VOLEMIA
Page 172 and 173: HEMOTHERAPIC PROTOCOL TO FALCIFORM
Page 174 and 175: 5 - TRANSFUSIONAL CONDUCT AT THE SE
Page 176 and 177: CML - Subjects with symptoms relate
Page 178 and 179: - Aplastic anemia bearers - HIV pos
Page 180 and 181: Severe reaction: anaphylactic shock
Page 182 and 183: - Heart monitoring - Prescribe Furo
Page 184 and 185: CARES AT THE PLATELETS CONCENTRATE
Page 186 and 187: ATTACHMENT I - HEMATOLOGICAL CLINIC
Page 188 and 189: INFECTIOUS SPLENO MEGALIES IMMUNO L
Page 190 and 191: INVESTIGATION OF HEMORRHAGIC SYNDRO
Page 192 and 193: INVESTIGATION OF POLYGLOBULIAS: POL
Page 194 and 195: ATTACHMENT III - HEMATOLOGY SPECIAL
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IMMUNOPHENOTYPE PROFILE OF THE ACUT
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ATTACHMENT IV - PAIN APPROACH ROUTI
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If it is prescribed for more than 1
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HOW TO PRESCRIBE OPIOID: SPECIAL CA
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SPECIFICITIES OF EACH OPIATE (cont
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METHADONE Intravenous (*) Oral path
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Psychic Dependence or “addiction
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CROSS TOLERANCE - The subject must
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ATTACHMENT V - CHEMOTHERAPY SUBJECT
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ATTACHMENT VII - IRON CHELATION GEN
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10. G N N - DFP DFP-100 mg/kg/day d
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ATTACHMENT VIII - SEDATION IN CHILD
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224 NOTES _________________________
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224 NOTES _________________________
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Expresso Gráfica e Editora Ltda-me
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