Protocols - Hemorio

MAIN BLOOD COMPONENTS
1 – WHOLE BLOOD
DESCRIPTION: It is the blood donated with no change, which will be processed at the hemocomponents
described below. Practically not used. There are few indications of whole blood transfusion. The quantity
of clotting factors is not enough and the platelets are no longer viable. The concentrate of red blood cells
supply more efficiently than the whole blood, the replacement of erythrocytes, with the advantage to infuse
a small volume.
2 – CONCENTRATE OF RED BLOOD CELLS:
DESCRIPTION: It comes from a whole blood bag, which was centrifuged. It can also be obtained by
apheresis collection.
SPECIAL PREPARATIONS: Concentrate of Low-Volume Red Blood Cells; Concentrate of Apheresis Red
Blood Cells; Concentrate of Irradiated Red Blood Cells; Concentrate of de-leukocyte Red blood cells and
Concentrate of Washed Red Blood Cells.
PRESERVATION AND CONSERVATION: The anti-clotting-preservative solution of the collection bag
may be CPDA1, in this case the Concentrate of Red Blood Cells will be valid for 35 days. If this solution is
added to an additive solution such as SAG- MANNITOL, the validity of the bag will extend up to 42 days.
The conservation temperature is 1º C - 6 0 C.
SELECTION: The Concentrates of Red blood cells must be consistent to ABO antibodies present at the
receptor serum. The Compatibility Proof must be executed before each transfusion (except for the
requests of “extreme urgency”). See RDC 153 as of June 14, 2004.
INDICATION: For subjects with symptomatology of deficiency in the capacity of oxygen entrainment or
with tissular hypoxia due to the number of insufficient circulating red blood cells. They are also indicated at
the Exsanguine Transfusion (Disease Hemolytic of the Newborn) and at the Change Transfusion for
subjects with Falciform Disease.
CONTRAINDICATIONS: The Concentrates of Red blood cells must not be used to treat anemias that can
be corrected with non-transfusional therapy, such as iron replacement and recombinant erythropoietin.
They must also not be used as a source of blood volume, oncotic pressure, clotting factors and platelets.
3 – CONCENTRATE OF PLATELETS:
DESCRIPTION: The concentrate of Whole Blood Platelets is obtained from a donation of whole blood,
through successive centrifuges. It can also be obtained by apheresis .
SPECIAL PREPARATIONS: Platelets / Platelets of Irradiated Apheresis, Pool of Platelets, Platelets /
Platelets of De-leukocytal Apheresis.
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