Protocols - Hemorio

AGE RANGE DRUG TERMINAL HALF-LIFE (h) DOSE AND FREQUENCY (mg/h)
AAS 0.2 – 0.3 500 / 6
ADULTS
DICLOFENAC
IBRUPOFEN
1.5 - 2
2 - 3
30 - 75 / 12
600 / 8
INDOMETHACIN 6 - 8 50 - 75 / 8
AGE RANGE DRUG DOSE (mg/Kg) No. DOSES / DAY
MAXIMUM DOSE
(mg/Kg/d)
ACETAMINOPHEN 10 - 15 4 - 6 60
CHILDREN
AAS
IBUPROFEN
10 - 15
5 - 10
4 - 6
3 - 4
60
40
INDOMETHACIN 1 3 3
5 - OPIOID:
CLASSIFICATION OF OPIOID:
CLASS DRUG ALTERNATIVE
PURE AND WEAK AGONIST CODEINE TRAMADOL HYDROCHLORIDE
PURE AND STRONG AGONIST MORPHINE
201
FENTANYL
BUPRENORPHINE HYDROCHLORIDE
NALBUFINE HYDROCHLORIDE
METHADONE
COEFFICIENT FOR THE DOSES CALCULATION:
ORAL MORPHINE PARENTERAL MORPHINE
ORAL MORPHINE 1 1 / 2
PARENTERAL MORPHINE X 2 X 1
PARENTERAL PETHIDINE 1 / 3 1 / 7.5
ORAL CODEINE 1 / 8 1 / 20
METHADONE 1 / 10 1 / 10
PARENTERAL BUPREMORPHINE X 0.016 X 0.04
SUBLINGUAL BUPREMORPHINE X 0.03 X 0.08
OPIOID DOSES (ONSET OF THE TREATMENT):
OPIOID TYPE INITIAL DOSE (EV) INITIAL DOSE (VO)
< 50 Kg > 50 Kg < 50 Kg > 50 Kg
MORPHINE 0.1 mg/Kg
2.5 - 5 mg
0.3 mg/Kg
5 - 10 mg
each 3 - 4 h
each 3 - 4 h
each 3 - 4 h
each 3 - 4 h
PETHIDINE 0.75 mg/Kg
50 - 100 mg
_ _
each 2 - 3 h
each 3 h
METHADONE Attack – 0.05 - 015 mg/Kg
IM / SC
Maintenance – 0.1 – 0.4 mg/Kg IM / IV - 2 - 4
days