Protocols - Hemorio

RESPONSE CRITERIA
Full Response
Absence of monoclonal protein in the serum and urine by Immunofixation
< 5 % of Plasmocyte at MO ( myelogram and BMB)
No increase in the size and number of lithic injuries
Disappearance of plasmacytoma of soft tissues
Partial Response
> 50 % of decrease in the serum monoclonal protein
Decrease in the excretion of mild chains in the urine in > 90% or to < 200mg/24 hours
Non-secretor myeloma decrease > 50% of plasmocytes at MO
Decrease > 50% at the soft tissues plasmacytoma
No increase in the size and number of lithic injuries
Minimum Response
Decrease of 25 to 49% of serum monoclonal protein
50 to 89% of decrease at the excretion of the mild chains in the urine (>200mg/24h)
Non-Secretor Myeloma
25 to 49% of decrease at the plasma cells of MO
25 to 49% of decrease in the size of soft tissues plasmacytoma
No increase in the size and number of lithic injuries
146