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Protocols - Hemorio

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ATTACHMENT VIII – SEDATION IN CHILDREN<br />

LOCAL – Invasive procedures room (ground floor, 6 th , 7 th or 8 th )<br />

RESOURCES<br />

AVAILABLE<br />

KETAMINA<br />

PROTOCOL<br />

KETAMINA EFFECTS<br />

CONTRAINDICATIONS<br />

ANTAGONIST OF<br />

BENZODIAZEPINE<br />

(FLUMAZENIL)<br />

MIDAZOLAN<br />

– O2 output with continuous flow;<br />

– Ambu (child and adult) with a O2 reservoir and mask (child, adult and<br />

teenager);<br />

– Tubes of different gauges, Guedel cannule;<br />

– Drugs: adrenaline, atropine, muscle relaxing, lasix, lidocaine, gliconate,<br />

benzodiazepine antagonist (Flumazenil).<br />

Initial dose<br />

Dilution<br />

cares<br />

Clinical<br />

cares<br />

– Intravenous – 0.025 – 1 mg/Kg (start 1 – 2 min)<br />

– Intramuscular – 5 – 6 mg/Kg (start 5 – 10 min)<br />

– You may repeat 5 minutes thereafter, if the sedation is<br />

improper, until the total dose of 2mg/Kg<br />

– Flask ampule 1ml = 50mg<br />

– Dilution in distilled water or SF<br />

– Fasting of 4-6h, before all procedures, no matter the<br />

administration path of the sedative;<br />

– All sedatives require vigilance and monitoring during and after<br />

the procedure (ASA, AAP, SBA and CFM);<br />

– Half-life of 2h, but the child starts waking up in 30 min, after<br />

the last dose. He can go home, provided that he is able to<br />

walk (usually in 90 min).<br />

– Only dose IM is used for combative children who refuse to<br />

perform the procedure.<br />

– Horizontal nistagmus or staring (sedation sign)<br />

– Dissociate sedation;<br />

– Induces a fast unconsciousness, with a spontaneous breathing<br />

– Increase of PA, FC and PIC<br />

– Sialorrhea, being indicated a dose of Atropine of 0.01mg/Kg, because the<br />

secretion may cause a laryngeal stimulation and cough;<br />

– In older children, it may present delirium, which may be prevented with the<br />

usage of small, not repeated doses of Benzodiazepine (midazolam 0.03 to<br />

0.1 mg/Kg)<br />

– It must not be used in force of HIC, aneurism, thyreotoxycosis, CHF, angina<br />

and psychiatric states<br />

– The antagonist has a half-life smaller than benzodiazepine, and a resedation<br />

may occur. If the dose has been given in excess, keep the child<br />

under observation;<br />

– The Dose 0.1mg/Kg (you may repeat every 1 minute, if there is no<br />

response, up to the total of the cumulative dose of 1-3mg in 1h).<br />

Initial Dose - 0.1 to 0.3/kg<br />

- Maximum dose – 10 mg in bolus 5 – 10 minutes in AD<br />

- If necessary, repeat in 15 to 20 minutes 50% of the initial dose.<br />

218

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