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Protocols - Hemorio

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TABLE 3: TREATMENT OF HEMOPHILIAS<br />

TYPE OF<br />

HEMORRHAGIA<br />

Superficial wound<br />

Deep wound<br />

Epistaxis<br />

Large muscular<br />

hematoma<br />

FVIII<br />

% IU %<br />

FIX<br />

IU<br />

FREQUENCY (h)<br />

FVIII FIX<br />

DURA<br />

TION<br />

(days)<br />

GENERAL MEASURES<br />

Compressive curative<br />

- - - - - - - Gelfoan + Ice on site<br />

40 20 40 40 24/24 24/24 2 a 3 Suture<br />

Antifibrinolytic<br />

30<br />

15<br />

30<br />

65<br />

30<br />

24/24<br />

24/24<br />

1<br />

repeat<br />

I/N<br />

Antibiotics<br />

bilateral nasal pressure<br />

Tamponage with glove<br />

finger<br />

Antifibrinolytic<br />

ORL Opinion<br />

Ecchymosis - - - - - - - Ice on site<br />

Superficial hematoma - - - - - - - Ice on site<br />

Small muscular<br />

hematoma<br />

30 15 30 30 24/24 24/24 2 to 3<br />

Ice on site<br />

Immobilization<br />

40-50 20-25 40-50 40-50 24/24 24/24 3 to 5<br />

Ice on site<br />

Immobilization<br />

Large muscular<br />

hematoma / risk sites /<br />

neurological<br />

impairment<br />

Hemarthrosis (early<br />

treatment or small<br />

volume)<br />

Hemarthrosis (late or<br />

volume treatment), hip,<br />

shoulder or target<br />

articulation<br />

hemarthrosis)<br />

Hematuria<br />

80-100 40-50 80-100 80-100 1 st dose 1 st dose 3 to 7 Ice on site<br />

50% 1 st<br />

dose<br />

50% 1 st<br />

dose<br />

50% 1 st<br />

dose<br />

50% 1 st<br />

dose<br />

12/12 12/12 Until<br />

recove<br />

ry<br />

40 20 40 40 24/24 24/24 1-3<br />

40 – 50 20 - 25 40 - 50 40 - 50 12/12 24/24 3-5<br />

30 15 30 30 DU DU<br />

Repea<br />

t I/N<br />

Immobilization<br />

Physiotherapy<br />

Bed rest<br />

Ice on site<br />

Oral hydration<br />

Etiology investigation<br />

DO NOT USE<br />

ANTIFIBRINOLYTIC<br />

Hemoptysis severe<br />

cases<br />

50 25 50 50 1st dose 1st 50% 1<br />

dose<br />

st<br />

dose<br />

50% 1st dose<br />

50% 1st dose<br />

50% 1st dose<br />

24/24 24/24 3 -5<br />

High or low digestive<br />

hemorrhage<br />

80-100 40-50 80-100 80-100 1st dose 1st 50% 1<br />

dose Until 3 Antifibrinolytic<br />

Hemostatic packed<br />

Endoscopy<br />

st<br />

dose<br />

50% 1st dose<br />

50% 1st dose<br />

50% 1st dose<br />

12/12 12/12 After<br />

resolv<br />

ed<br />

Daily neurological<br />

Mild CET 50 25 50 50 24/24 24/24 3-5 evaluation + TCC<br />

100 50 100 100 1<br />

Severe CET without<br />

neurological change<br />

st dose 1st Daily neurological<br />

dose evaluation<br />

50% 1<br />

14<br />

Minimum level 2/2d<br />

Bed rest<br />

DO NOT USE<br />

ANTIFIBRINOLYTIC<br />

st<br />

dose<br />

50% 1st dose<br />

50% 1st dose<br />

50% 1st dose<br />

12/12 24/24

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