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Protocols - Hemorio

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HEMOTHERAPIC PROTOCOL TO FALCIFORM DISEASE AND SURGERY<br />

The subject must be sent by the clinical Hematology, through an opinion, indicating if it is released under<br />

the hematological point of view for the proposed surgery. This opinion must bear the probable date of the<br />

surgical procedure. Do not attend the subject without the medical folder.<br />

SMALL SIZE<br />

(AMBULATORIES)<br />

Local anesthesia:<br />

biopsies in general<br />

MEDIUM AND BIG<br />

SIZE<br />

General anesthesia:<br />

cholecystectomy,<br />

hernias in general,<br />

splenectomy,<br />

orthopedic, cardiac<br />

surgeries,<br />

neurosurgeries, etc.<br />

FLOWCHART TO<br />

BE FOLLOWED<br />

Do not need<br />

hemotherapic<br />

preparation<br />

Medium Size: Let<br />

the subject with<br />

levels of HbS < or =<br />

50%<br />

Big Size: Let the<br />

subject with levels of<br />

HbS < or = 30%,<br />

The subjects must perform Full hemogram tests and dosage of<br />

Hemoglobin A and S at least 47 hours before the hemotherapic<br />

preparation. It must be evaluated if the subject is submitted to the simple<br />

or change transfusion.<br />

Simple transfusion = it will be applied when the subject presents<br />

hemoglobin value ≤ 6.0 g/dl, or presents at the tests a decrease of 20 %<br />

at the hematimetric baseline values.<br />

Change transfusion = it will be applied in all subjects with Hemoglobin ><br />

6.0 g/dl and HbS > 50%.<br />

The preparation must be performed up to 62 hours before the surgery,<br />

being mandatory at the end of the procedure, an order of a new full<br />

hemogram and dosage of HbS. If the subject presents any clinical<br />

intercurrence at the preparation day, tell your assistant physician<br />

through the Clinical Boss.<br />

HEMOTHERAPIC PROTOCOL OF SPLENIC SEQUESTRATION:<br />

HYPERTRANSFUSION PROGRAM:<br />

INDICATION 0- to 2-year old children who have presented splenic sequestration<br />

HCT and baseline Hb (transfusion indicated when there is a decrease of 20 % in<br />

PARAMETERS<br />

VOLUME TO BE<br />

TRANSFUSED<br />

YES<br />

Preparation<br />

conclusion up to<br />

03:00 p.m.?<br />

NO<br />

these parameters)<br />

5ml/Kg, until the hemodynamics stabilization is reached. The subject must attend,<br />

fortnightly, the Hemotherapy Service according to the topical specifications “Splenic<br />

Sequestration”. After 2 years old, splenectomy is automatically indicated.<br />

TRANSFUSIONAL PROTOCOL OF PREGNANT WOMEN WITH FALCIFORM DISEASE:<br />

ASYMPTOMATIC Hb ≥ 7g/dL - Do not transfuse, evaluate every 10 days<br />

SYMPTOMATIC with a decrease of - Perform a simple transfusion.<br />

20 % of baseline hematimetric values - Reevaluate every week.<br />

SYMPTOMATIC with baseline<br />

hematimetric levels (ATS, algic crisis<br />

moderate to intense, toxemia, fetal<br />

distress with risk of abortion).<br />

Ask for hemogram and dosage of<br />

HbS for the same day.<br />

Perform change transfusion – keep HbS ≤ 50 %<br />

- Reevaluate in 24 hours.<br />

- Make a reservation of red blood cells concentrate at the<br />

previous week to the hospitalization for the delivery<br />

TRANSFUSIONAL PROTOCOL OF SUBJECTS WHO HAVE SUFFERED CVA:<br />

TIA and CVA Start the change transfusion immediately after the diagnosis<br />

Hemorrhagic CVA Do not make any change transfusion, if necessary just simple transfusion<br />

Change of D.T.C. Include the subject at the change program, before an opinion of the Hematology and<br />

Neurology.<br />

172<br />

Hb reached the<br />

desired level?<br />

Ask for the hemogram and<br />

dosage of HbS for the next day.<br />

YES<br />

Release the<br />

surgery with the<br />

document of<br />

Hemotherapy<br />

NO Reevaluate the<br />

transfusion

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