here - Australian College of Veterinary Scientists
here - Australian College of Veterinary Scientists
here - Australian College of Veterinary Scientists
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Authors recommendations:<br />
1. Both Imaverol ® (0.2% enilconazole rinse) and Malaseb ® (2% chlorhexidine<br />
2% miconazole, Dermcare Vet) appear effective at reducing the duration <strong>of</strong><br />
disease. I am happy to use either and recommend weekly to twice weekly whole<br />
body treatments<br />
2. I also recommend the use <strong>of</strong> Lamisil ® ointment (terbinafine) to individual<br />
lesions w<strong>here</strong> practical twice daily<br />
3. I do not recommend the use <strong>of</strong> systemic antifungals in horses with<br />
dermatophytosis<br />
4. I find concurrent bacterial folliculitis uncommon with the exception <strong>of</strong> disease<br />
involving the lower limbs. This generally responds to Trimidine powder 15 to<br />
30mg/kg bid for 3 to 4 weeks.<br />
5. I have no personal experience with dermatophytic pseudomycetoma but the<br />
literature suggests these lesions are usually singular and surgery is curative.<br />
Environmental decontamination:<br />
1. Washable surfaces, tack, blankets grooming equipment should be treated with<br />
0.2% enilconazole twice at 10 day intervals.<br />
2. Tack, grooming equipment should not be shared with other horses.<br />
3. Straw, bedding materials that are not treatable should be destroyed.<br />
Prophylaxis<br />
1. Recovered animals are unlikely to be infected again.<br />
2. Attenuated live and inactivated T. equinum vaccines have been used in Europe<br />
and the USA respectively. Vaccines were administered intramuscularly on two<br />
occasions, 14 days apart. Both vaccines were effective at preventing or reducing<br />
the severity <strong>of</strong> disease with both experimental and naturally occurring challenges.<br />
Points for discussion.<br />
1. IDEXX laboratories report zero equine dermatophyte cultures in the last 18<br />
months. Is identifying the species important?<br />
2. Topically applied porphyrins followed by UVA therapy has been shown to be<br />
effective in human dermatophytosis. This may support the anecdotal reports that<br />
equine dermatophytosis resolves more rapidly in sunny conditions.<br />
3. Trichophyton spp antigens have been demonstrated to cause IgE mediated<br />
reactions in humans with asthma and clinical severity <strong>of</strong> asthma has been<br />
reduced with antifungal therapy. Any role for antifungal therapy in COPD in<br />
horses?<br />
ACVSC Proceedings Dermatology Chapter Science Week 2005 109