15.08.2013 Views

here - Australian College of Veterinary Scientists

here - Australian College of Veterinary Scientists

here - Australian College of Veterinary Scientists

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

The allergens used for equine skin testing tend to be the same that is used for small<br />

animal testing, and <strong>of</strong>ten allergen selection has occurred with small animals in mind.<br />

Additional horse-specific allergens such as Culicoides are also included for the equine<br />

tests. W<strong>here</strong> horses are housed in the same metropolitan area, it is assumed that<br />

exposure to similar allergens as small animals will occur. However, modifications to<br />

the allergen selection may be necessary for horses from more distant country areas.<br />

It is not apparent whether particular allergens are relevant in horses, as their lifestyle<br />

may prevent significant exposure to various substances; such as insects (cockroach),<br />

House-dust mites and pollens from fodder materials brought into the area rather than<br />

grown in the area. Testing with epithelia (from other animals and humans) is not<br />

possible in Australia due to quarantine regulation against the importation <strong>of</strong> such<br />

allergens, so the significance <strong>of</strong> these is unknown in the <strong>Australian</strong> context. In one<br />

study in affected horses, positive intradermal test reactions to epithelia were seen in a<br />

significant number <strong>of</strong> clinically affected horses (54.2% to human dander!)(2).<br />

Allergen mixes are available, but testing with these is not recommended (1), as the<br />

concentration <strong>of</strong> the individual allergens in the mix becomes too dilute for detection.<br />

Variation in species <strong>of</strong> insect and pollen allergens may also be important. The<br />

Culicoides extract available through Greer laboratories is derived from Culicoides<br />

nebiculosis. In Australia, Culicoides brevitarsis is considered to be the only relevant species<br />

<strong>of</strong> Culicoides (at least in NSW, according to entomologists at the Elizabeth Macarthur<br />

Agricultural Institute - pers comm.). Information from Greer suggests that crossreactivity<br />

across most species <strong>of</strong> Culicoides can be expected, but the reality <strong>of</strong> this<br />

assumption is not known.<br />

20<br />

ACVSC Proceedings Dermatology Chapter Science Week 2005

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!