here - Australian College of Veterinary Scientists
here - Australian College of Veterinary Scientists
here - Australian College of Veterinary Scientists
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treatment is given.<br />
This danger was overcome by the use <strong>of</strong> a BCG cell wall vaccine preparation<br />
which was as effective as the living BCG vaccine but does not have the<br />
adverse side effects <strong>of</strong> producing anaphylaxis (Hepler & Leuker 1980).The<br />
reported use <strong>of</strong> such a vaccine (CSL Equoid Australia) for the intradermal<br />
treatment <strong>of</strong> sarcoid gave favourable results with 1-2 injections 14-21 days<br />
apart in 80% <strong>of</strong> the cases treated.(Vaneslow et al 1988). Production problems<br />
with this vaccine led to its permanent withdrawal from the market in 1993.<br />
4. Surgical treatment<br />
Surgical excision– removal <strong>of</strong> sarcoid, under local or general anaesthetic, plus<br />
at least 15-20mm ring <strong>of</strong> normal. Disadvantages: 50% may return and as<br />
wound heals may spread to other areas on the horse; removal <strong>of</strong> large areas<br />
<strong>of</strong> normal skin precludes closure and slowshealing time; inability to remove<br />
this quantity <strong>of</strong> skin from leg lesions increases risk <strong>of</strong> return<br />
CO2 Laser Complete ablasion for small Sarcoids id very successful large<br />
tumours can be less well ablated and may reoccur<br />
5. Electrocautery<br />
W<strong>here</strong> single small masses are involved ordinary cautery is satisfactory but reoccurrence<br />
can be expected. With large electrocautery units, both cutting and<br />
fulguration are available and should be used: remove tumour by cutting<br />
current then treat area, particularly the skin edges, with fulguration to<br />
desiccate tissue.<br />
6. Cryosurgery<br />
Useful for Sarcoids. Complications are under or over treatment; injury to<br />
surrounding blood vessels, nerves, bone and tendon. The success <strong>of</strong><br />
cryotherapy depends on correct technique.(Fretz & Barbour 1987)<br />
Cryonecrosis therapy - The success or otherwise <strong>of</strong> cryotherapy rests in<br />
proper observation <strong>of</strong> correct technique. The following summary assists in<br />
understanding the modality and its side effects.<br />
Cryosurgery summary<br />
(i)Select adequate 'heat' sink (best is liquid N2)<br />
(ii)Freeze tissues rapidly to below -20C<br />
(iii)Allow slow thaw to +36C<br />
(iv)Repeat cycle 2-3 times<br />
(v)Restrict circulation to area using tourniquet<br />
(vi)Protect surrounding tissue with Polystyrene<br />
(vii)Hair follicles are destroyed by double cycle<br />
(viii)Vitiligo occurs with a single freeze thaw cycle; scars with double cycle<br />
ACVSC Proceedings Dermatology Chapter Science Week 2005
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