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years, median age 6.5 years, with age <strong>of</strong> onset <strong>of</strong> disease 1-27 years (median 5.5 years)<br />

and duration <strong>of</strong> clinical signs at time <strong>of</strong> referral ranging from 2 months to >5years.<br />

Fourteen <strong>of</strong> the horses presented with pruritus and six with pruritus and urticaria.<br />

Four horses had recurrent or chronic urticaria without obvious pruritus, including<br />

one with angio-oedema. The degree <strong>of</strong> pruritus was considered to be severe in six<br />

animals, and was particularly severe in case 3 (see figure 1) resulting in self inflicted<br />

damage and requiring the use <strong>of</strong> a nosebag to prevent biting. In most cases the<br />

clinical signs were restricted to the trunk, with tail rubbing also present in seven,<br />

mane involvement in two and facial irritation noted occasionally. Papules or<br />

“bumps” were reported or found on dermatological examination in six cases. Two<br />

horses had histories <strong>of</strong> intercurrent respiratory problems thought to be <strong>of</strong> allergic<br />

aetiology on the basis <strong>of</strong> previous investigations (endoscopy and cytological<br />

examination <strong>of</strong> tracheo-bronchial washes). In 12 horses the clinical signs were<br />

perennial, with exacerbation in the summer noted in two and winter exacerbation in<br />

two others. Four animals showed a seasonal pattern to their skin problem, one <strong>of</strong><br />

which was restricted to spring, two to the winter and the fourth to the summer. This<br />

latter horse was only stabled in the summer and turned out all winter. In eight<br />

animals the duration <strong>of</strong> clinical signs was not long enough to determine if the<br />

problem was going to be perennial, but in six the signs began in autumn or winter<br />

and two started with symptoms in late summer or autumn. All animals were stabled<br />

for at least 50% <strong>of</strong> the day, with 15 horses being stabled full time at the time <strong>of</strong><br />

maximal clinical signs.<br />

Diagnosis:<br />

A large number <strong>of</strong> differential diagnoses may need to be considered, depending on<br />

the history and distribution <strong>of</strong> clinical signs, but would include:<br />

insect hypersensitivity<br />

ectoparasites (lice, chorioptic mange, psoroptic mange, trombiculidiasis,<br />

poultry mites)<br />

oxyuriasis<br />

forage/storage mites<br />

helminth infestations (oxyuriasis, strongyloidosis, Pelodera cutaneous larval<br />

migrans)<br />

contact dermatitis<br />

adverse cutaneous food reaction<br />

drug reactions<br />

systemic diseases causing pruritus (rare cases <strong>of</strong> lymphoma, hepatic and renal<br />

neoplasia)<br />

As in the dog and cat, the diagnosis <strong>of</strong> atopic dermatitis is reached after ruling out all<br />

other possible differentials and the diagnosis is essentially a clinical diagnosis.<br />

Laboratory investigations such as routine haematological and biochemical pr<strong>of</strong>iles<br />

are rarely contributory to reaching a diagnosis in atopic horses, but may be indicated<br />

to investigate possible systemic disease in cases with suggestive clinical signs. Skin<br />

ACVSC Proceedings Dermatology Chapter Science Week 2005 13

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