here - Australian College of Veterinary Scientists
here - Australian College of Veterinary Scientists
here - Australian College of Veterinary Scientists
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Erythema multiforme<br />
Rare, acute, self-limiting, urticarial, maculopapular or vesico-bullous dermatosis. Other<br />
triggering influences such as drugs, infections (especially Herpes virus), and tumours -<br />
especially lymphoreticular neoplasms. Many cases are classified as idiopathic.<br />
Aetiology / Pathophysiology<br />
Can be considered a type <strong>of</strong> allergic response, being very similar to graft versus host<br />
reaction.<br />
Clinical presentation<br />
Lesions tend to have a symmetrical distribution. Asymptomatic cutaneous eruptions.<br />
Characteristic 'donut like' skin urticarial lesions develop rapidly from initial urticaria and<br />
plaques. Occasionally involves mucous membranes <strong>of</strong> mouth. Persist from days to<br />
weeks. No scaling, crusting or alopecia in many horses. These plaques do not pit on<br />
pressure<br />
Differential diagnosis<br />
Urticaria, amyloidosis, mastocytoma, lymphosarcoma, fixed drug reaction, toxic<br />
epidermal necrolysis.<br />
Diagnosis<br />
Skin biopsy.<br />
Management<br />
Runs benign course over 2-3 months. Recurrence reported in some cases.<br />
Prognosis<br />
Guarded to poor for permanent recovery.<br />
46<br />
ACVSC Proceedings Dermatology Chapter Science Week 2005