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24. Scott, D.W. (1992) Diagnostic des dermatoses inflammatoires équines :analyse de la modalité de réaction histopathologique:étude personelle portant sur 315 cas. Point Vétérinaire 24, 245-248 25. Scott, D.W. and Miller, W.H. (2003) Miscellaneous skin diseases. In Equine Dermatology. New York, Elsevier Health. pp 675-680 26. Sellers, R.S., Toribio, R.E. & Blomme, E.A. (2001) Idiopathic systemic granulomatous disease and macrophage expression of PTHrP in a miniature pony. Journal of Comparative Pathology 125, 214-218 27. Spiegel, I.B., White S.D. et al. (2005) Retrospective study of cutaneous equine sarcoidosis and potential underlying infectious etiologies. 20th Proceedings of North American Veterinary Dermatology Forum, 166. 28. Stannard, A.A. (1987) Generalized granulomatous disease. In Current Therapy in Equine Medicine. 2nd edn. Eds N.E. Robinson. Philadelphia, W.B. Saunders. pp 645-646 29. Strickland-Marmol, L.B., Fessler, R.G. & Rojiani, A.M. (2000) Necrotizing sarcoid granulomatosis mimicking an intracranial neoplasm: clinicopathologic features and review of the literature. Modern Patholology 13, 909-913 30. Veien, N.K. (1986) Cutaneous sarcoidosis: prognosis and treatment. Clinical Dermatology 75-87 31. von Tscharner, C., Kunkle, G. & Yager, J. (2000) Stannard´s illustrated equine dermatology notes. Veterinary Dermatology 11, 161-223 32. Waldinger, T.P., Ellis, C.N., Quint, K. & Voorhees, J.J. (1983) Treatment of cutaneous sarcoidosis with isotretinoin. Archives of Dermatology 119, 1003- 1005 33. Weedon, D. (2002) Skin Pathology. 2nd edn. London, Churchill Livingstone. pp 194-195 34. Woods, L.W., Johnson, B., Hietala, S.K., Galey, F.D. & Gillen, D. (1992) Systemic granulomatous disease in a horse grazing pasture containing vetch (Vicia sp.). Journal of Veterinary Diagnostic Investigation 4, 356-360 35. Yamada, H., Ide, A., Sugiura, M. & Tajima, S. (1995) Treatment of cutaneous sarcoidosis with tranilast. Journal of Dermatology 22, 149-152 36. Zic, J.A., Horowitz, D.H., Arzurbiaga, C. & King, L.E.J. (1991) Treatment of cutaneous sarcoidosis with chloroquine. Archives of Dermatology 127, 1034- 1040 66 ACVSC Proceedings Dermatology Chapter Science Week 2005
Introduction The equine sarcoid: an update Reg Pascoe A locally aggressive fibroblastic tumour which is probably the most common cutaneous tumour found in horses. Prevalent in horses aged between 1-6 years.(Torrentegui & Reid 1994: Pascoe & Knottenbelt 1999) The lesions are frequently not life threatening but they can severely limit the use of the horse and reduce its sale prospects, however euthanasia is not uncommon due to the prolonged nature of treatment, likelihood of recrudescence of the problem and cost The role of a virus, in particular Bovine papillomavirus (BPV), in its cause and transmission is still uncertain Population and family studies have shown an association between sarcoid susceptibility and MHC class II alleles (Lazary et al., 1985, 1994) Some research indicated there were no mutations of the somatic tumour suppressor p53 gene in either horses or donkeys associated with the development of sarcoids More recently somatic p53 gene mutations have been found to be associated with the development of some sarcoid tumours in donkeys (Nasir et al 1999). BPV-DNA was detected in 88% and 91% of the successful swabs and scrapings from sarcoids respectively. The overall diagnostic sensitivity of the technique was significantly lower compared to the clinical diagnosis of sarcoids and is unsuitable for occult sarcoids. However, the detection of BPV-DNA in all samples obtained from sarcoids with an ulcerated surface opens new perspectives for the detection of sarcoid involvement in wounds or recurrence after sarcoid removal.(Martens et al 2001) In a further study BPV DNA was detected in essentially all sarcoids examined (96/98) it was also detected in normal skin samples from the horses with sarcoids suggesting the possibility of a latent viral phase. Viral latency may be one explanation of the high rate of recurrence following surgical removal. All tissues from healthy horses with non sarcoid neoplasms or papilloma were negative to BVP DNA ( Carr et al 2001) Lesions occur in locations which are prone to injury and some have a history of previous skin wounds. There is also strong presumptive evidence that sarcoids can be transmitted by biting and domestic flies which feed on sarcoid tissue and then browse on other horses with open sores, wounds or tumours. The introduction of a ACVSC Proceedings Dermatology Chapter Science Week 2005 67
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Australian College of Veterinary Sc
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Australian College of Veterinary Sc
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3.00 Afternoon tea 3.30 How I treat
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Dr Jennifer A. Charles BVSc MVS Dip
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Scientists in Feline Medicine in 19
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IgE-bearing cells have been demonst
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years, median age 6.5 years, with a
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Page 17 and 18: References: Evans AG, Paradis MR, &
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Page 21 and 22: TABLE 1: CURRENT ALLERGENS SELECTED
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Page 41 and 42: Introduction Diagnostic Approach to
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Page 45 and 46: References Evans AG, Paradis MR & O
Page 47 and 48: Introduction: Equine Chronic Urtica
Page 49 and 50: Acute treatment - Epinephrine 1:100
Page 51 and 52: anecdotal success with use of human
Page 53 and 54: an 80:20 mixture of evening primros
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Page 57 and 58: identify plants in a pasture that m
Page 59 and 60: Equine sarcoidosis Sonya Bettenay T
Page 61 and 62: described as a possible feature of
Page 63 and 64: others 2001), isotretinoin(Waldinge
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Page 69 and 70: Clinical Presentation Small fibrous
Page 71 and 72: Assessment should be made on the fo
Page 73 and 74: (ix)Bone becomes devitalized if inc
Page 75 and 76: and mitomycin C have been used. All
Page 77 and 78: Owen LN & Barnett KC (1983) - Treat
Page 79 and 80: any anatomic location but commonly
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Page 83 and 84: References D.C. Knottenbelt, S. Edw
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Page 91 and 92: Affected horses usually scratch and
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Page 95 and 96: How I treat: equine pemphigus folia
Page 97 and 98: Treatment of pemphigus foliaceus in
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Page 101 and 102: Diagnosis History of access of hors
Page 103 and 104: These vaccines are not manufactured
Page 105 and 106: References Alfaro AA & Mendoza L (1
Page 107 and 108: y a variety of fungal metabolites.
Page 109 and 110: Authors recommendations: 1. Both Im
Page 111 and 112: chorioptic mange by the author (Lit
Page 113 and 114: Clinical Disease The clinical resul
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Notes ACVSC Proceedings Dermatology
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