04.11.2014 Views

manual on management of drugs

manual on management of drugs

manual on management of drugs

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

unobservable (animal dead, killed, missing or stray animal) initiate PET and<br />

c<strong>on</strong>tinue the full course.<br />

The patient must be clearly advised that the animal should be put in a cage or<br />

leashed during the observati<strong>on</strong> period. If the animal dies, becomes sick or<br />

develop any abnormal behaviour, the patient should be advised to report to the<br />

hospital immediately. In case <strong>of</strong> death <strong>of</strong> the animal patient should be<br />

encouraged to send the head <strong>of</strong> the animal for laboratory c<strong>on</strong>firmati<strong>on</strong> <strong>of</strong><br />

rabies.<br />

The following are not c<strong>on</strong>sidered as exposures:<br />

a. C<strong>on</strong>taminati<strong>on</strong> <strong>of</strong> intact skin with saliva <strong>of</strong> a suspected animal.<br />

b.Petting, bathing or coming in c<strong>on</strong>tact with utensils <strong>of</strong> a suspected rabid<br />

animal.<br />

4.0 Anti Rabies PET: When indicated:<br />

4.1 All patients in the major category should be given rabies immunoglobulin<br />

(Equine or Human) followed by a course <strong>of</strong> anti rabies vaccine (ARV).<br />

4.2 Patients in the minor category should be given <strong>on</strong>ly a course <strong>of</strong> ARV<br />

5.0 Rabies Immunoglobulins(RIG)<br />

5.1 RIG available in Sri Lanka at present:<br />

a. Equine rabies immunoglobulin (ERIG)<br />

b. Human rabies immunoglobulin(HRIG)<br />

Administrati<strong>on</strong> <strong>of</strong> RIG should be c<strong>on</strong>sidered as an emergency. Rabies<br />

immunoglobulin should be given immediately after the incident. However if<br />

the patient reports late, RIG could be given up to 3 m<strong>on</strong>ths after exposure, if<br />

the patient has not taken the anti rabies vaccine.<br />

It is essential to test for sensitivity before administering ERIG, Method <strong>of</strong><br />

sensitivity testing (ST) for ERIG is given in annexure IV. HRIG does not<br />

require sensitivity testing prior to its administrati<strong>on</strong>.<br />

If a patient with a major exposure is ST positive for all available products <strong>of</strong><br />

Equine-RIG, Human RIG should be c<strong>on</strong>sidered.<br />

However, in a situati<strong>on</strong> where HRIG is not available in the country:<br />

a. If the animal is apparently healthy and observable, the 8 site ID - ARV<br />

67

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!