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2010 AnnuAl REpoRT - Ciberdem

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Proinsulin and tyrosine hydroxilase in development<br />

and differentiation<br />

Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Madrid<br />

www.cib.csic.es<br />

Principal Investigator Flora de Pablo fdepablo@cib.csic.es Associate researcher Catalina Hernández Postdoctoral fellow Patricia<br />

Vázquez Lab technician Cayetana Murillo<br />

Total IF: 4.395<br />

Publications: 1, in the first quartile<br />

With other CIBERDEM groups: 1<br />

Research grants: 1<br />

National projects: 1<br />

Patents: 1<br />

Keywords<br />

Catecholamines. Hormone receptors. Proinsulin. Islet<br />

development. Insulin sensitivity and resistance.<br />

Main lines of research<br />

To characterize TH expression pattern in mouse pancreas<br />

development and the analysis of TH function by studying<br />

pancreatic cell markers in TH-/- developing mice.<br />

Publications*<br />

Original article<br />

Signaling and biological effects of glucagon-like peptide<br />

1 on the differentiation of mesenchymal stem cells from<br />

human bone marrow<br />

Sanz C, Vázquez P, Blázquez C, Barrio PA, Alvarez M del<br />

M, Blázquez E<br />

Am J Physiol Endocrinol Metab, 298, E634-643 (<strong>2010</strong>)<br />

IF: 4.395 first quartile. With other CIBERDEM groups:<br />

E Blázquez<br />

Research grants<br />

National project<br />

Transcritos quimera y otras formas atípicas de regulación<br />

génica y sus implicaciones en el desarrollo temprano<br />

Ministerio de Ciencia e Innovación, BFU2007-61055: 2007-<strong>2010</strong><br />

Principal Investigator: Flora de Pablo<br />

Patents<br />

National patent<br />

Uso de la proinsulina para la elaboración de una<br />

composición farmacéutica neuroprotectora, composición<br />

*Only those published in <strong>2010</strong>, with CIBERDEM listed among the affiliations, which are related to CIBERDEM’s field of research and are<br />

located in the first or second quartile of their subject category are included.<br />

<strong>2010</strong> Annual Report<br />

107

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