Obesity and insulin resistance-related changes in the expression of lipogenic and lipolytic genes in morbidly obese subjects Tinahones FJ, Garrido-Sanchez L, Miranda M, García-Almeida JM, Macias-Gonzalez M, Ceperuelo V, Gluckmann E, Rivas-Marin J, Vendrell J, García-Fuentes E Obes Surg, 20, 1559-1567 (<strong>2010</strong>) Obesity impairs general health-related quality of life (HR-QoL) in premenopausal women to a greater extent than polycystic ovary syndrome (PCOS) Alvarez-Blasco F, Luque-Ramírez M, Escobar-Morreale HF Clin Endocrinol, 73, 595-601 (<strong>2010</strong>) Olive oil and health: summary of the II international conference on olive oil and health consensus report, Jaén and Córdoba (Spain) 2008 López-Miranda J, Pérez-Jiménez F, Ros E, De Caterina R, Badimón L, Covas MI, Escrich E, Ordovás JM, Soriguer F, Abiá R, de la Lastra CA, Battino M, Corella D, Chamorro-Quirós J, Delgado-Lista J, Giugliano D, Esposito K, Estruch R, Fernandez- Real JM, Gaforio JJ, La Vecchia C, Lairon D, López-Segura F, Mata P, Menéndez JA, Muriana FJ, Osada J, Panagiotakos DB, Paniagua JA, Pérez-Martinez P, Perona J, Peinado MA, Pineda-Priego M, Poulsen HE, Quiles JL, Ramírez-Tortosa MC, Ruano J, Serra-Majem L, Solá R, Solanas M, Solfrizzi V, de la Torre-Fornell R, Trichopoulou A, Uceda M, Villalba-Montoro JM, Villar-Ortiz JR, Visioli F, Yiannakouris N Nutr Metab Cardiovasc Dis, 20, 284-294 (<strong>2010</strong>) Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction Hennige AM, Ranta F, Heinzelmann I, Düfer M, Michael D, Braumüller H, Lutz SZ, Lammers R, Drews G, Bosch F, Häring HU, Ullrich S Diabetes, 59, 119-127 (<strong>2010</strong>) Paired subcutaneous and visceral adipose tissue aquaporin-7 expression in human obesity and type 2 diabetes: differences and similarities between depots Miranda M, Escoté X, Ceperuelo-Mallafré V, Alcaide MJ, Simón I, Vilarrasa N, Wabitsch M, Vendrell J J Clin Endocrinol Metab, 95, 3470-3479 (<strong>2010</strong>) Pancreas and kidney transplantation: long-term endocrine function Mora M, Ricart MJ, Casamitjana R, Astudillo E, López I, Jiménez A, Fernández-Cruz L, Esmatjes E Clin Transplant, 24, E236-E240 (<strong>2010</strong>) Pancreatic islet cells: a model for calcium-dependent peptide release Soria B, Tuduri E, Gonzalez A, Hmadcha A, Martin F, Nadal A, Quesada I HFSP Journal, 4, 52-60 (<strong>2010</strong>) Pitavastatin - from clinical trials to clinical practice Masana L Atheroscler Suppl, 11, 15-22 (<strong>2010</strong>) Review Placental FTO expression relates to fetal growth Bassols J, Prats-Puig A, Vázquez-Ruíz M, García-González MM, Martínez-Pascual M, Avellí P, Martínez-Martínez R, Fàbrega R, Colomer-Virosta C, Soriano-Rodríguez P, Díaz M, de Zegher F, Ibánez L, López-Bermejo A Int J Obes, 34, 1365-1370 (<strong>2010</strong>) Plasma homocysteine levels are associated with ulceration of the foot in patients with type 2 diabetes mellitus González R, Pedro T, Real JT, Martínez-Hervás S, Abellán MR, Lorente R, Priego A, Catalá M, Chaves FJ, Ascaso JF, Carmena R Diabetes Metab Res Rev, 26, 115-120 (<strong>2010</strong>) Polyunsaturated fatty acids down-regulate in vitro expression of the key intestinal cholesterol absorption protein NPC1L1: no effect of monounsaturated nor saturated fatty acids <strong>2010</strong> Annual Report 139
Alvaro A, Rosales R, Masana L, Vallvé JC J Nutr Biochem, 21, 518-525 (<strong>2010</strong>) Position paper: Rapid responses to steroids: current status and future prospects Wendler A, Baldi E, Harvey BJ, Nadal A, Norman A, Wehling M Eur J Endocrinol, 162, 825-830 (<strong>2010</strong>) Editorial PPARgamma expression after a high-fat meal is associated with plasma superoxide dismutase activity in morbidly obese persons Garcia-Fuentes E, Murri M, Garrido-Sanchez L, Garcia-Serrano S, García-Almeida JM, Moreno-Santos I, Tinahones FJ, Macias-Gonzalez M Obesity (Silver Spring), 18, 952-958 (<strong>2010</strong>) PP2A regulatory subunit PP2A-B’ counteracts S6K phosphorylation Hahn K, Miranda M, Francis VA, Vendrell J, Zorzano A, Teleman AA Cell Metab, 11, 438-444 (<strong>2010</strong>) Production, purification and characterization of adeno-associated vectors Ayuso E, Mingozzi F, Bosch F Curr Gene Ther, 10, 423-436 (<strong>2010</strong>) Review Progress in understanding postprandial dyslipidaemia: Second International Symposium on the Role of Chylomicrons in Disease l Watts GF, Ribalta J Atheroscler Suppl, 11, 1-2 (<strong>2010</strong>) Editorial Proof-of-concept trial on the efficacy of sodium tungstate in human obesity Hanzu F, Gomis R, Coves MJ, Viaplana J, Palomo M, Andreu A, Szpunar J, Vidal J Diabetes Obes Metab, 12, 1013-1018 (<strong>2010</strong>) Protein intake, body composition, and protein status following bariatric surgery Andreu A, Moizé V, Rodríguez L, Flores L, Vidal J Obes Surg, 20, 1509-1515 (<strong>2010</strong>) Proteomic analysis of plasma in the polycystic ovary syndrome identifies novel markers involved in iron metabolism, acute-phase response, and inflammation Insenser M, Martínez-García MA, Montes R, San-Millán JL, Escobar-Morreale HF J Clin Endocrinol Metab, 95, 3863-3870 (<strong>2010</strong>) PTP1B deficiency enhances liver growth during suckling by increasing the expression of insulin-like growth factor-I Escrivá F, González-Rodriguez A, Fernández-Millán E, Rondinone CM, Alvarez C, Valverde AM J Cell Physiol, 225, 214-222 (<strong>2010</strong>) Pubertal metformin therapy to reduce total, visceral, and hepatic adiposity Ibáñez L, Lopez-Bermejo A, Diaz M, Marcos MV, de Zegher F J Pediatr, 156, 98-102e1 (<strong>2010</strong>) Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis Garin I, Edghill EL, Akerman I, Rubio-Cabezas O, Rica I, Locke JM, Maestro MA, Alshaikh A, Bundak R, del Castillo G, Deeb A, Deiss D, Fernandez JM, Godbole K, Hussain K, O’Connell M, Klupa T, Kolouskova S, Mohsin F, Perlman K, Sumnik Z, Rial JM, Ugarte E, Vasanthi T; Neonatal Diabetes International Group, Johnstone K, Flanagan SE, Martínez R, Castaño C, Patch AM, Fernández-Rebollo E, Raile K, Morgan N, Harries LW, Castaño L, Ellard S, Ferrer J, Perez de Nanclares G, Hattersley AT Proc Natl Acad Sci U S A, 107, 3105-3110 (<strong>2010</strong>) 140 CibeRdem
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2010 Annual Report CIBERDEM Centro
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Letter from the Scientific Director
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Contents Prologue Research results
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Research results Publications In 20
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Project management Introduction The
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Training programme Introduction The
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Outreach activities CIBERDEM Fundra
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More about CIBERDEM The Centro de I
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Human Resources In 2010, CIBERDEM h
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Transversal projects Di@bet.es Stud
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Di@bet.es Study Introduction Attemp
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CIBERDEM Projects Introduction CIBE
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girls (girls born small for gestati
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Biobank Introduction and objectives
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Metabolomics Platform Introduction
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Area 1 Insulin signalling and resis
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Diabetes and cardiovascular Faculta
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Metabolomics Platform Universitat R
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Obesity, inflammation and insulin r
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Mechanisms of control of glucose an
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Metabolic engineering and diabetes
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Molecular mechanisms of insulin res
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Molecular characteristics, and acti
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Heterogenic and polygenic diseases.
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Principal Investigator: Antonio Zor
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The research activity of this area
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The cationic cluster of group IVA p
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agent that affects the enterohepati
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Dyslipidaemia, inflammation and end
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Daño orgánico en la diabetes mell
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Proteomic analysis of plasma in the
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Prenatal growth restriction and sub
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The effects of metformin on cardiov
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Lipids and Arteriosclerosis Researc
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Review Pitavastatin - from clinical
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Diabetobe Hospital Clínico San Car
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Scientific collaborations within CI
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Atherosclerosis, 209, 201-205 (2010
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Solvay, SA: 2008-2010 Principal Inv
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Endocrinology and Nutrition Service
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Prevención de la Diabetes mellitus
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Pharmacological targets in inflamma
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Diabetes and Metabolic Associated D
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