2010 AnnuAl REpoRT - Ciberdem

Dyslipidaemia, inflammation and endothelial
dysfunction
Servicio de Endocrinología y Nutrición, Fundación Investigación Hospital Clínico Universitario de Valencia
www.fihcuv.es
Principal Investigator Rafael Carmena rafael.carmena@uv.es Associate researchers Juan Francisco Ascaso, Miguel Catalá, Felipe Javier
Chaves, Sergio Martínez Hervás, José Tomás Real Postdoctoral fellows Ana Bárbara García, Marta Peiró Lab manager Sebastián Blesa
Lab technicians Esther Benito, Clara María Bixquert, Nieves Brito, Griselda de Marco
Total IF: 17.452
Publications: 5, 1 of them in the first decile, 2 in the first quartile
and 2 in the second quartile
With other CIBERDEM groups: 1
With other CIBERs: 4
Research grants: 3
National projects: 2
Autonomous Community projects: 1
Scientific collaborations within CIBERDEM: 4
PhD theses: 1
Keywords
Insulin sensitivity and resistance. Lipid metabolism.
Macrovascular disease. Metabolic syndrome. Weight
regulation and obesity.
Main lines of research
The degree of arterial damage and age of onset of
arteriosclerosis varies in patients with primary dyslipidaemias
or diabetes, indicating the existence of other contributing
factors. We have investigated the role of oxidative stress
(OS), inflammation, insulin resistance, and prediabetic states
as possible candidates.
Our research lines include: primary hyperlipidaemias
- genetic diagnosis and cardiovascular risk; primary
mixed hyperlipidaemias - insulin resistance and diabetes
mellitus; postprandial lipidaemia and arteriosclerosis in
insulin-resistant states; insulin resistance, inflammation
and oxidative stress; diabetic foot - diagnosis, prevention
and treatment; and genetic factors regulating BMI and
abdominal obesity.
Publications*
Original articles
Association of selected ABC gene family single nucleotide
polymorphisms with postprandial lipoproteins: results from
*Only those published in 2010, with CIBERDEM listed among the affiliations, which are related to CIBERDEM’s field of research and are
located in the first or second quartile of their subject category are included.
2010 Annual Report
59