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2010 AnnuAl REpoRT - Ciberdem

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Lipids and Arteriosclerosis Research Unit<br />

Institut d’Investigació Sanitària Pere Virgili, Hospital Universitari Sant Joan de Reus<br />

www.iispv.cat<br />

Principal Investigator Lluís Masana luis.masana@urv.cat Research directors Josep Ribalta, Rosa Solà Senior researchers Anna Cabré,<br />

Joan Carles Vallvé Associate researcher Núria Plana Nutritionist Jordi Merino Postdoctoral fellows Montserrat Guardiola, Rosa Maria Valls<br />

PhD students Gemma Aragonès, Úrsula Catalán, Raimon Ferré, Marta González, Iolanda Lázaro, Isabel Martorell, Anna Pedret, Paula<br />

Saavedra Lab manager Josefa Girona Lab technicians Mercedes Heras, Carme Buixadera, Sara Fernández, Roser Rosales Administrative<br />

staff Sílvia Solé<br />

Total IF: 49.910<br />

Publications: 12, 6 of them in the first decile, 5 in the first quartile<br />

and 1 in the second quartile<br />

With other CIBERDEM groups: 4<br />

With other CIBERs: 5<br />

With other international groups: 1<br />

Research grants: 4<br />

National projects: 4<br />

Scientific collaborations within CIBERDEM: 3<br />

Clinical trials: 4<br />

Spin-offs: 1<br />

PhD theses: 4<br />

Awards: 1<br />

Keywords<br />

Genetics type 2 diabetes. Insulin sensitivity and resistance.<br />

Metabolic syndrome. Biomarkers and Imaging. Prevention<br />

of type 2 diabetes. Endothelium. Macrovascular disease.<br />

Nutrigenomics.<br />

Main lines of research<br />

-Atherogenic dyslipidaemia in diabetes, obesity and<br />

metabolic syndrome.<br />

-The characterization of plasma lipoprotein subclasses by<br />

NMR, metabolomics and lipidomics.<br />

-Adipose tissue dysfunction as a major determinant of AD.<br />

-Fatty Acid-Binding Proteins (FABPs) and insulin resistance<br />

in different tissues.<br />

-Fatty acids and adipokine-induced endothelial dysfunction.<br />

-AD and subclinical atherosclerosis.<br />

-FFA, extracellular matrix and artery wall dysfunction in diabetes.<br />

-The epigenetics of atherosclerosis.<br />

<strong>2010</strong> Annual Report<br />

69

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