2010 AnnuAl REpoRT - Ciberdem

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Altirriba J, Gasa R, Casas S, Ramírez-Bajo MJ, Ros S, Gutierrez-Dalmau A, Ruiz de Villa MC, Barbera A, Gomis R Diabetologia, 53, 1406-1414 (2010) IF: 6.551 first decile. With other CIBERDEM groups: R Gomis Research grants European project Epigenetic control of gene expression in pancreatic islets European Foundation for the Study of Diabetes (EFSD)-Lilly Research Fellowship: 2010 Principal Investigator: Joan Marc Servitja National projects The role of the BACE enzyme (beta-site amyloid precursor protein cleaving enzyme) in pancreatic islet function Ministerio de Sanidad y Consumo, PI080088: 2009-2011 Principal Investigator: Anna Novials Associate investigators: Sílvia Casas, Paola Casini, Maud Soty Design, characterization and follow-up of training designed to produce metabolic improvements in type 2 diabetic patients Ministerio de Ciencia e Innovación, DPS2008-06922: 2009-2011 Principal Investigator: Joan Aureli Cadefau Associate investigator: Anna Novials A study of the pancreatic islet response to hypoxia: role of HIF-1 Ministerio de Educación y Ciencia, BFU2006-09072/BFI. PI015429: 2006-2010 Principal Investigator: Joan Marc Servitja Autonomous Community project A study of the effect of human albumin versus human serum on the culture and transplant of human islets Centre de Medicina Regenerativa de Barcelona (CMRB), Generalitat de Catalunya, PROMT_0901-3: 2009-2010 Principal Investigators: Anna Novials, Eduard Montanya CIBERDEM groups: A Novials, E Montanya Scientific collaborations within CIBERDEM Comparative metabolomic analysis for the detection of biomarkers in diabetes METADIAB: 2009-2010 Coordinator: Xavier Correig CIBERDEM groups: A Novials, X Correig, R Gomis Mechanisms of endothelial dysfunction in diabetes: the role of amylin and circulating endothelial cells ENDODIAB: 2009-2010 Coordinator: Anna Novials CIBERDEM groups: A Novials, R Gomis, ML Villanueva Peñacarrillo CIBERDEM Biobank Coordinator: Anna Novials Exercise test at the Diabetes and Exercise Unit. 2010 Annual Report 125
CIBERDEM Biobank Nodes: A Novials, R Gomis, J Vendrell, L Masana, L Castaño, M Serrano Ríos, F Soriguer, R Carmena, F Blanco Vaca Clinical trials Multicenter trial, international, randomized and 2x2 factorial to assess the effects of Lantus (glargin insulin) compared to the standard treatment with omega 3 fatty acids compared to placebo, in the decrease in cardiovascular morbility and mortality in high risk patients with altered fasting glucose (AFG), decrease in glucose tolerance (TGD) or type 2 diabetes in initial steps. Phase III Sanofi-Aventis: 2004-in progress Researcher: Anna Novials ■ 126 CibeRdem
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2010 Annual Report CIBERDEM Centro
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Letter from the Scientific Director
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Contents Prologue Research results
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Research results Publications In 20
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Project management Introduction The
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Training programme Introduction The
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Outreach activities CIBERDEM Fundra
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More about CIBERDEM The Centro de I
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Human Resources In 2010, CIBERDEM h
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Transversal projects Di@bet.es Stud
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Di@bet.es Study Introduction Attemp
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CIBERDEM Projects Introduction CIBE
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girls (girls born small for gestati
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Biobank Introduction and objectives
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Metabolomics Platform Introduction
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Area 1 Insulin signalling and resis
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Diabetes and cardiovascular Faculta
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Metabolomics Platform Universitat R
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Obesity, inflammation and insulin r
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Mechanisms of control of glucose an
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Metabolic engineering and diabetes
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Molecular mechanisms of insulin res
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Molecular characteristics, and acti
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Heterogenic and polygenic diseases.
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Principal Investigator: Antonio Zor
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The research activity of this area
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The cationic cluster of group IVA p
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agent that affects the enterohepati
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Dyslipidaemia, inflammation and end
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Daño orgánico en la diabetes mell
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Proteomic analysis of plasma in the
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Prenatal growth restriction and sub
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The effects of metformin on cardiov
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Lipids and Arteriosclerosis Researc
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Review Pitavastatin - from clinical
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Diabetobe Hospital Clínico San Car
Page 76 and 77: Scientific collaborations within CI
Page 78 and 79: Atherosclerosis, 209, 201-205 (2010
Page 80 and 81: Solvay, SA: 2008-2010 Principal Inv
Page 82 and 83: Endocrinology and Nutrition Service
Page 84 and 85: Prevención de la Diabetes mellitus
Page 86 and 87: Pharmacological targets in inflamma
Page 88 and 89: Diabetes and Metabolic Associated D
Page 90 and 91: Autonomous Community project Grup d
Page 92 and 93: Area 3 of CIBERDEM comprises thirte
Page 94 and 95: Escrivá F, Alvarez C J Mol Endocri
Page 96 and 97: Am J Physiol Endocrinol Metab, 298,
Page 98 and 99: Transgenic animal models and gene t
Page 100 and 101: Ayuso E, Mingozzi F, Bosch F Curr G
Page 102 and 103: Laboratory of Molecular Endocrinolo
Page 104 and 105: Hospital de Cruces Diabetes Researc
Page 106 and 107: Research grants International proje
Page 108 and 109: Proinsulin and tyrosine hydroxilase
Page 110 and 111: Genomic programming of beta cells I
Page 112 and 113: Diabetes and obesity: biopathology
Page 114 and 115: Utilidad de la ecografía arterial
Page 116 and 117: Islet cell and stem cell physiology
Page 118 and 119: in diabetic patients with chronic c
Page 120 and 121: Liraglutide versus sitagliptin for
Page 122 and 123: Unit of Cell Physiology and Nutriti
Page 124 and 125: National projects Efectos a corto y
Page 128 and 129: Transcriptional mechanisms of pancr
Page 131 and 132: Epilogue
Page 133 and 134: Keyword index* Beta-cell signal tra
Page 135 and 136: Association of selected ABC gene fa
Page 137 and 138: Leiter LA, Levitt NS, Mareev V, Mar
Page 139 and 140: Low body adiposity and high leptine
Page 141 and 142: Alvaro A, Rosales R, Masana L, Vall
Page 143 and 144: The apolipoprotein A5 (APOA5) gene
Page 145 and 146: www.ciberdem.org/annualreport CIBER
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2010 AnnuAl REpoRT - Ciberdem

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