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2010 AnnuAl REpoRT - Ciberdem

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Biobank<br />

Introduction and objectives<br />

The CIBERDEM Biobank is a scientific and technological<br />

platform which coordinates the collection, processing,<br />

storage and retrieval of biological samples in the field of<br />

diabetes and other metabolic diseases, which may then<br />

be utilized by CIBERDEM research groups and by other<br />

scientific institutions in their experiments and projects. The<br />

Biobank, thanks to its experience and expertise in this field,<br />

holds one of the most important collections of samples of<br />

metabolic disorders in southern Europe, bringing great<br />

added value to the biomedical research conducted by<br />

CIBERDEM. Structured into nodes with multiple collection<br />

and processing sites, the Biobank allows for the immediate<br />

storage of samples following blood extraction in order to<br />

ensure the highest quality possible. Through the centralized<br />

coordination of sample management, the Biobank also<br />

ensures the traceability of its samples, as required by<br />

the recently passed Biomedical Research Act. The<br />

Coordinating Node of the CIBERDEM Biobank obtained the<br />

ISO9001 quality certification in December 2009.<br />

Scientific services<br />

The main services provided by the Biobank consist of the<br />

following:<br />

Design and management of a large metabolic disorder<br />

sample collection, involving donor recruitment; data<br />

registration; informed consent management; serum and<br />

plasma storage; DNA purification and storage; lymphocyte<br />

isolation and immortalization; and quality management.<br />

Assurance of traceability.<br />

Quality control of the stored samples.<br />

Organization of an internal database for the analysis of<br />

samples and data.<br />

Management of sample request proposals through the<br />

coordination of the Scientific External Committee and the<br />

Ethics Committee.<br />

Personalized assistance in sample management.<br />

Coordinating Node<br />

IDIBAPS, Barcelona: Principal Investigators Ramon Gomis,<br />

Anna Novials Coordinator Anna Bosch Associate researcher<br />

Laura Brugnara Lab technician Anna Morales Lab manager<br />

Albert Davins Lab technician and quality control manager<br />

Roser Mas Nurse Laura Tugores<br />

Nodes<br />

Hospital Joan XXIII, Tarragona: Principal Investigator Joan<br />

Vendrell Research assistant Lluís Gallart Lab technician<br />

Miriam Campos<br />

www.clinicbiobanc.org<br />

Hospital Sant Joan, Reus: Principal Investigator Lluís<br />

Masana Research assistants Jordina Saladié, Jordi Merino<br />

Lab technician Carme Buixadera<br />

Hospital de Cruces, Barakaldo: Principal Investigator Luis<br />

Castaño Research assistant and lab manager Inés Urrutia<br />

Research assistant and dietician Teba González<br />

Hospital Clínico San Carlos, Madrid: Principal Investigator<br />

Manuel Serrano Ríos PhD student Carina Zabena Lab<br />

technician Mari Carmen Obiang<br />

Hospital Civil, Málaga: Principal Investigator Federico<br />

Soriguer Associate researcher Gemma Rojo Research<br />

assistant Francisca Linares Nurse Mª José Moreno<br />

Hospital Clínico, Valencia: Principal Investigator Rafael<br />

Carmena Associate researcher Javier Chaves Research<br />

assistant Esther Benito Lab technician Verónica González<br />

Hospital de Sant Pau, Barcelona: Principal Investigator<br />

Francesc Blanco Vaca Associate researcher Jesús Martín<br />

Lab technician and Nurse Cristina Martín<br />

Facilities<br />

The Coordinating Node of the Biobank centralizes the<br />

organization of Biobank sample management and is thus<br />

endowed with the most advanced technology available<br />

for this purpose: automated DNA extraction platform<br />

(Chemagen system, magnetic beads); liquid handling<br />

station (Tecan EVO150), cell immortalization facility<br />

(P2 level safety lab); liquid nitrogen tanks; continuous<br />

<strong>2010</strong> Annual Report<br />

27

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