2010 AnnuAl REpoRT - Ciberdem

Diabetes, Obesity and Reproductive Endocrinology
Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS and Universidad de Alcalá,
Madrid
www.hrc.es
Principal Investigator Héctor F Escobar Morreale hescobarm.hrc@salud.madrid.org Associate researchers Francisco Álvarez Blasco,
Susana Borruel Nacenta, María Rosa Insenser, Manuel Luque Ramírez, David Martí Sánchez, María Ángeles Martínez, Rafael Montes,
José Luis San Millán PhD student Macarena Alpañés Lab manager Elena Fernández
Total IF: 19.260
Publications: 5, 2 of them in the first decile and 3 in the second
quartile
Research grants: 1
National projects: 1
Scientific collaborations within CIBERDEM: 1
Clinical trials: 1
Clinical practice guidelines: 1
Keywords
Biomarkers and Imaging. Insulin sensitivity and resistance.
Polycystic ovary syndrome. Proteomics. Metabolic surgery.
Main lines of research
The influence of the balance between androgens and
oestrogens on the development of abdominal adiposity
and visceral adipose tissue dysfunction in humans as
pathogenetic factors of insulin resistance and diabetes,
including:
a) an integrated approach to the influence of sex
hormones on the amount and dysfunction of visceral and
subcutaneous fat as studied by clinical research, molecular
genetics, molecular biology, genomics, proteomics and
metabolomics.
b) the identification of pathogenetic markers of diabetes in
severe obesity and predictors of diabetes remission after
bariatric surgery.
Publications*
Original articles
Obesity impairs general health-related quality of life (HR-
QoL) in premenopausal women to a greater extent than
polycystic ovary syndrome (PCOS)
Alvarez-Blasco F, Luque-Ramírez M, Escobar-Morreale HF
Clin Endocrinol, 73, 595-601 (2010)
IF: 3.201 second quartile
*Only those published in 2010, with CIBERDEM listed among the affiliations, which are related to CIBERDEM’s field of research and are
located in the first or second quartile of their subject category are included.
62 CibeRdem