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2010 AnnuAl REpoRT - Ciberdem

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Dev Biol, 346, 346-355 (<strong>2010</strong>)<br />

IF: 4.379 first decile. With other international groups<br />

Nitric oxide repression of Nanog promotes mouse<br />

embryonic stem cell differentiation<br />

Mora-Castilla S, Tejedo JR, Hmadcha A, Cahuana GM,<br />

Martín F, Soria B, Bedoya FJ<br />

Cell Death Differ, 17, 1025-1033 (<strong>2010</strong>)<br />

IF: 8.240 first quartile<br />

Pancreatic islet cells: a model for calcium-dependent<br />

peptide release<br />

Soria B, Tuduri E, Gonzalez A, Hmadcha A, Martin F, Nadal<br />

A, Quesada I<br />

HFSP Journal, 4, 52-60 (<strong>2010</strong>)<br />

IF: 1.600 first quartile. With other CIBERDEM groups: A Nadal<br />

Research grants<br />

National projects<br />

TERCEL Network<br />

Instituto de Salud Carlos III, RD06/0010/0025: <strong>2010</strong>-2011<br />

Principal Investigator: Bernat Soria<br />

Associate investigators: Franz Martín, Karim Hmdcha,<br />

Francisco Bedoya, Juan Tejedo<br />

Molecular characterization of protective action of NO on<br />

the pancreatic beta-cell<br />

Ministerio de Ciencia e Innovación, SAF-2007-602105:<br />

2007-<strong>2010</strong><br />

Principal Investigator: Francisco J Bedoya<br />

Associate investigators: Gladys M Cahuana, Juan R Tejedo<br />

The role of GATA4 transcription factor in endoderm and<br />

pancreas development<br />

Instituto de Salud Carlos III, PI108/0018: 2009-2011<br />

Principal Investigator: Anabel Rojas<br />

Diabetes mellitus cell therapy: the role of intercellular<br />

signalling pathways and intracellular material transfer<br />

Instituto de Salud Carlos III, PI-10/00964: <strong>2010</strong>-2013<br />

Principal Investigator: Bernat Soria<br />

Associate investigators: Franz Martín, Karim Hmadcha,<br />

Miguel Martín, Lourdes Acosta, Ana Serna, Alfredo<br />

Santana, Rafael Ruiz, Antonio de la Cuesta, Inmaculada<br />

Pérez Camacho, Yolanda Aguilera, Mónica Navarro<br />

Cell therapy for critical lower-limb ischemia in type<br />

2 diabetes insulinized patients: a study of insulin<br />

demand<br />

MSPS/Dirección General de terapias Avanzadas, TRA-120:<br />

<strong>2010</strong>-2012<br />

Principal Investigator: Bernat Soria<br />

Associate investigators: Karim Hmadcha, Rafael Ruiz,<br />

Antonio de la Cuesta, Inmaculada Pérez Camacho,<br />

Franz Martín<br />

Autonomous Community projects<br />

The role of endothelial factors in the obtention of insulinsecreting<br />

cells from adult pancreatic stem cells<br />

Consejería de Salud, Junta de Andalucía, PI00022/2008:<br />

2009-2012<br />

Principal Investigator: Franz Martín<br />

Associate investigators: Patricia Moreno, Elvira León,<br />

Verónica Rivero, Javier Navarro<br />

NO regulation of mouse and human beta-cell and<br />

pancreatic islet survival during the isolation process<br />

Consejería de Salud, Junta de Andalucía, PI0095/07:<br />

2008-2011<br />

Principal Investigator: Juan R Tejedo<br />

Associate investigators: Francisco J Bedoya, Gladys M Cahuana<br />

Transcriptional control during endoderm pancreas development<br />

Consejería de Salud, Junta de Andalucía, PI0008/10:<br />

<strong>2010</strong>-2012<br />

Principal Investigator: Anabel Rojas<br />

Associate investigators: Raquel Araujo<br />

Monoclonal antibody characterization<br />

Fundación Progreso y Salud: <strong>2010</strong>-2011<br />

Principal Investigator: Franz Martín<br />

Associate investigators: Genoveva Berná, Gladys M Cahuana<br />

Scientific collaborations within CIBERDEM<br />

The production of monoclonal antibodies which selectively<br />

react with cell surface molecules on human pancreatic<br />

beta cells<br />

ANTIBECELL: 2009-<strong>2010</strong><br />

Coordinator: Juan Tejedo<br />

CIBERDEM groups: F Martín, E Montanya, A Nadal<br />

Clinical trials<br />

Intraarterial infusion of autologous mesenchymal stem cells<br />

from adipose tissue in diabetic patients with chronic critical<br />

limb ischemia. Phases I and II<br />

IATA (Iniciativa Andaluza de Terapias Avanzadas),<br />

(CeTMAd/ICPD2008), ClinicalTrials.gov NCT01079403:<br />

<strong>2010</strong>-2011<br />

Name of the participants: Ruiz R, De la Cuesta A, Soria B,<br />

Hmadcha K<br />

Cellular therapy for type 2 diabetic patients with CLI: Study<br />

of Insulin needs. Phases I and II<br />

IATA (Iniciativa Andaluza de Terapias Avanzadas),<br />

(CeTMOTa/ICPDI/<strong>2010</strong>) CT <strong>2010</strong>-019774-33: <strong>2010</strong>-2011<br />

Name of the participants: Ruiz R, De la Cuesta A, Soria B,<br />

Hmadcha K<br />

Multicenter clinical trial for the evaluation of intraarterial<br />

infusion of autologous marrow derived mononuclear cells<br />

116 CibeRdem

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