2010 AnnuAl REpoRT - Ciberdem
2010 AnnuAl REpoRT - Ciberdem
2010 AnnuAl REpoRT - Ciberdem
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Mechanisms of control of glucose and<br />
fatty acid metabolism in skeletal muscle cells<br />
and metabolic impairment in atrophy<br />
Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona<br />
www.bq.ub.es<br />
Principal Investigator Anna Maria Gómez Foix agomezfoix@ub.edu Associate researcher Cèlia García Martínez Research assistants Maria<br />
Guitart de la Rosa, Marta Montori Grau PhD students Emma Mormeneo Beltran, Oscar Osorio Conles Lab manager Anna Orozco García<br />
Total IF: 12.862<br />
Publications: 3, 1 of them in the first decile and 2 in the first quartile<br />
With other CIBERDEM groups: 1<br />
With other CIBERs: 1<br />
With other international groups: 1<br />
Research grants: 4<br />
National projects: 1<br />
Autonomous Community projects: 3<br />
Scientific collaborations within CIBERDEM: 1<br />
Keywords<br />
Insulin sensitivity and resistance. Lipid metabolism.<br />
Carbohydrate metabolism.<br />
Main lines of research<br />
-Mechanisms of control of skeletal muscle glycogen<br />
metabolism. Differential functionality of the protein<br />
phosphatase 1 (PP1) glycogen-associated regulatory<br />
subunits present in human skeletal muscle GM (PPP1R3A),<br />
PTG (PPP1R3C) and PPP1R6 (PPP1R3D).<br />
-Metabolic control role of the fatty acid transport protein<br />
1 (FATP1) in muscle and deleterious effect in high-fat-dietinduced<br />
diabetes.<br />
-Transcriptional and metabolic adaptations of noninnervated<br />
cultured primary human myotubes compared to<br />
human skeletal muscle.<br />
Publications*<br />
Original articles<br />
Activation of peroxisome proliferator-activated receptor-<br />
{delta} by GW501516 prevents fatty acid-induced nuclear<br />
factor-{kappa}B activation and insulin resistance in skeletal<br />
muscle cells<br />
Coll T, Alvarez-Guardia D, Barroso E, Gómez-Foix AM,<br />
Palomer X, Laguna JC, Vázquez-Carrera M<br />
Endocrinology, 151, 1560-1569 (<strong>2010</strong>)<br />
IF: 4.752 first quartile. With other CIBERDEM groups:<br />
M Vázquez Carrera<br />
*Only those published in <strong>2010</strong>, with CIBERDEM listed among the affiliations, which are related to CIBERDEM’s field of research and are<br />
located in the first or second quartile of their subject category are included.<br />
40 CibeRdem
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