2010 AnnuAl REpoRT - Ciberdem
2010 AnnuAl REpoRT - Ciberdem
2010 AnnuAl REpoRT - Ciberdem
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Unit of Cell Physiology and Nutrition IB-UMH<br />
Instituto de Bioingeniería, Universidad Miguel Hernández, Elx<br />
http://diabetes.umh.es<br />
Principal Investigator Angel Nadal nadal@umh.es Associate researchers Esther Fuentes, Elena García, Ivan Quesada, Cristina Ripoll,<br />
Ana Belén Ropero Postdoctoral fellows Paloma Alonso Magdalena, Sergi Soriano, Elaine Vieira PhD students Ernesto Caballero, Marta<br />
García Arévalo, Alejandro González, Laura Marroquí Lab technicians Pablo Juan Picó, María Luisa Navarro, Ana Belén Rufete<br />
Total IF: 26.703<br />
Publications: 7, 1 of them in the first decile, 4 in the first quartile<br />
and 2 in the second quartile<br />
With other CIBERDEM groups: 3<br />
With other international groups: 5<br />
Research grants: 4<br />
European projects: 1<br />
National projects: 2<br />
Autonomous Community projects: 1<br />
Scientific collaborations within CIBERDEM: 1<br />
Keywords<br />
Beta-cell signal transduction. Hormone receptors.<br />
Hormones (non-insulin), action. Insulin secretion. Insulin<br />
sensitivity and resistance. Cytokines.<br />
Main lines of research<br />
-The role of oestrogen receptors in the physiology of the<br />
islet of Langerhans. We study the actions of oestrogens<br />
and environmental oestrogenic pollutants in the function of<br />
pancreatic alpha and beta cells with an emphasis on the<br />
molecular mechanisms involved.<br />
-Signal transduction pathways involved in the function<br />
of alpha, beta and delta cells. We study the activation<br />
of signalling pathways by leptin receptors and its<br />
consequences in alpha- and beta-cell function.<br />
-The role of ANP (atrial natriuretic peptide)<br />
receptors in beta-cell function and blood glucose<br />
homeostasis.<br />
Publications*<br />
Original articles<br />
Bisphenol A exposure during pregnancy disrupts glucose<br />
homeostasis in mothers and adult male offspring<br />
Alonso-Magdalena P, Vieira E, Soriano S, Menes L, Burks D,<br />
Quesada I, Nadal A<br />
*Only those published in <strong>2010</strong>, with CIBERDEM listed among the affiliations, which are related to CIBERDEM’s field of research and are<br />
located in the first or second quartile of their subject category are included.<br />
<strong>2010</strong> Annual Report<br />
121
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