Publications index* A map of open chromatin in human pancreatic islets Gaulton KJ, Nammo T, Pasquali L, Simon JM, Giresi PG, Fogarty MP, Panhuis TM, Mieczkowski P, Secchi A, Bosco D, Berney T, Montanya E, Mohlke KL, Lieb JD, Ferrer J Nat Genet, 42, 255-259 (<strong>2010</strong>) A single nucleotide polymorphism in STK11 influences insulin sensitivity and metformin efficacy in hyperinsulinemic girls with androgen excess López-Bermejo A, Díaz M, Morán E, de Zegher F, Ibáñez L Diabetes Care, 33, 1544-1548 (<strong>2010</strong>) Activation of peroxisome proliferator-activated receptor-{delta} by GW501516 prevents fatty acid-induced nuclear factor- {kappa}B activation and insulin resistance in skeletal muscle cells Coll T, Alvarez-Guardia D, Barroso E, Gómez-Foix AM, Palomer X, Laguna JC, Vázquez-Carrera M Endocrinology, 151, 1560-1569 (<strong>2010</strong>) Activity-dependent somatostatin gene expression is regulated by cAMP-dependent protein kinase and Ca2+-calmodulin kinase pathways Sánchez-Muñoz I, Sánchez-Franco F, Vallejo M, Fernández A, Palacios N, Fernández M, Cacicedo L J Neurosci Res, 88, 825-836 (<strong>2010</strong>) Adenosine 5’-monophosphate-activated protein kinase-mammalian target of rapamycin cross talk regulates brown adipocyte differentiation Vila-Bedmar R, Lorenzo M, Fernández-Veledo S Endocrinology, 151, 980-992 (<strong>2010</strong>) Alterations in the mitochondrial regulatory pathways constituted by the nuclear co-factors PGC-1alpha or PGC-1beta and mitofusin 2 in skeletal muscle in type 2 diabetes Zorzano A, Hernández-Alvarez MI, Palacín M, Mingrone G Biochim Biophys Acta, 1797, 1028-1033 (<strong>2010</strong>) Review Alx3-deficient mice exhibit folic acid-resistant craniofacial midline and neural tube closure defects Lakhwani S, García-Sanz P, Vallejo M Dev Biol, 344, 869-880 (<strong>2010</strong>) APOH is increased in the plasma and liver of type 2 diabetic patients with metabolic syndrome Castro A, Lázaro I, Selva DM, Céspedes E, Girona J, Plana N, Guardiola M, Cabré A, Simó R, Masana L Atherosclerosis, 209, 201-205 (<strong>2010</strong>) *Only those published in <strong>2010</strong>, with CIBERDEM listed among the affiliations, which are related to CIBERDEM’s field of research and are located in the first or second quartile of their subject category are included. <strong>2010</strong> Annual Report 133
Association of selected ABC gene family single nucleotide polymorphisms with postprandial lipoproteins: results from the population-based Hortega study Abellán R, Mansego ML, Martínez-Hervás S, Martín-Escudero JC, Carmena R, Real JT, Redon J, Castrodeza-Sanz JJ, Chaves FJ Atherosclerosis, 211, 203-209 (<strong>2010</strong>) Asymptomatic sleep-disordered breathing in premenopausal women awaiting bariatric surgery Lecube A, Sampol G, Lloberes P, Romero O, Mesa J, Morell F, Simó R Obes Surg, 20, 454-461 (<strong>2010</strong>) BACE2 plays a role in the insulin receptor trafficking in pancreatic beta cells Casas S, Casini P, Piquer S, Altirriba J, Soty M, Cadavez L, Gomis R, Novials A Am J Physiol Endocrinol Metab, 299, E1087-E1095 (<strong>2010</strong>) Beneficial effects of PTP1B deficiency on brown adipocyte differentiation and protection against apoptosis induced by pro- and anti-inflammatory stimuli Miranda S, González-Rodríguez A, Revuelta-Cervantes J, Rondinone CM, Valverde AM Cell Signal, 22, 645-659 (<strong>2010</strong>) Bisphenol A exposure during pregnancy disrupts glucose homeostasis in mothers and adult male offspring Alonso-Magdalena P, Vieira E, Soriano S, Menes L, Burks D, Quesada I, Nadal A Environ Health Perspect, 118, 1243-1250 (<strong>2010</strong>) Carboxylation of osteocalcin affects its association with metabolic parameters in healthy children Prats-Puig A, Mas-Parareda M, Riera-Pérez E, González-Forcadell D, Mier C, Mallol-Guisset M, Díaz M, Bassols J, de Zegher F, Ibáñez L, López-Bermejo A Diabetes Care, 33, 661-663 (<strong>2010</strong>) Chronically increased glucose uptake by adipose tissue leads to lactate production and improved insulin sensitivity rather than obesity in the mouse Muñoz S, Franckhauser S, Elias I, Ferré T, Hidalgo A, Monteys AM, Molas M, Cerdán S, Pujol A, Ruberte J, Bosch F Diabetologia, 53, 2417-2430 (<strong>2010</strong>) Circulating bactericidal/permeability-increasing protein (BPI) is associated with serum lipids and endothelial function Esteve E, Castro A, Moreno JM, Vendrell J, Ricart W, Fernández-Real JM Thromb Haemost, 103, 780-787 (<strong>2010</strong>) Circulating mononuclear cells nuclear factor-kappa B activity, plasma xanthine oxidase, and low grade inflammatory markers in adult patients with familial hypercholesterolaemia Real JT, Martínez-Hervás S, García-García AB, Civera M, Pallardó FV, Ascaso JF, Viña JR, Chaves FJ, Carmena R Eur J Clin Invest, 40, 89-94 (<strong>2010</strong>) Comparative gene expression profiling between human cultured myotubes and skeletal muscle tissue Raymond F, Métairon S, Kussmann M, Colomer J, Nascimento A, Mormeneo E, García-Martínez C, Gómez-Foix AM BMC Genomics, 11, 125 (<strong>2010</strong>) Cyclin G2 regulates adipogenesis through PPAR gamma coactivation Aguilar V, Annicotte JS, Escote X, Vendrell J, Langin D, Fajas L Endocrinology, 151, 5247-5254 (<strong>2010</strong>) Cyclooxygenase 2 inhibition exacerbates palmitate-induced inflammation and insulin resistance in skeletal muscle cells Coll T, Palomer X, Blanco-Vaca F, Escolà-Gil JC, Sánchez RM, Laguna JC, Vázquez-Carrera M Endocrinology, 151, 537-548 (<strong>2010</strong>) 134 CibeRdem
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2010 Annual Report CIBERDEM Centro
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Letter from the Scientific Director
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Contents Prologue Research results
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Research results Publications In 20
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Project management Introduction The
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Training programme Introduction The
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Outreach activities CIBERDEM Fundra
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More about CIBERDEM The Centro de I
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Human Resources In 2010, CIBERDEM h
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Transversal projects Di@bet.es Stud
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Di@bet.es Study Introduction Attemp
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CIBERDEM Projects Introduction CIBE
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girls (girls born small for gestati
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Biobank Introduction and objectives
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Metabolomics Platform Introduction
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Area 1 Insulin signalling and resis
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Diabetes and cardiovascular Faculta
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Metabolomics Platform Universitat R
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Obesity, inflammation and insulin r
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Mechanisms of control of glucose an
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Metabolic engineering and diabetes
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Molecular mechanisms of insulin res
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Molecular characteristics, and acti
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Heterogenic and polygenic diseases.
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Principal Investigator: Antonio Zor
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The research activity of this area
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The cationic cluster of group IVA p
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agent that affects the enterohepati
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Dyslipidaemia, inflammation and end
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Daño orgánico en la diabetes mell
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Proteomic analysis of plasma in the
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Prenatal growth restriction and sub
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The effects of metformin on cardiov
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Lipids and Arteriosclerosis Researc
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Review Pitavastatin - from clinical
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Diabetobe Hospital Clínico San Car
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Scientific collaborations within CI
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Atherosclerosis, 209, 201-205 (2010
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Solvay, SA: 2008-2010 Principal Inv
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Endocrinology and Nutrition Service
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